Pandemic influenza viruses modulate proinflammatory responses that can lead to immunopathogenesis. We present an extensive and systematic profiling of lipids, metabolites, and proteins in respiratory compartments of ferrets infected with either 1918 or 2009 human pandemic H1N1 influenza viruses. Integrative analysis of high-throughput omics data with virologic and histopathologic data...
By means of a case study and historical analysis, this dissertation examines the past and present of avian influenza. By integrating disconnected histories of human and animal influenza, this dissertation links historical insights with the concerns of contemporary avian flu science. It is not only a natural history of avian...