BACKGROUND: Targeted capture of genomic regions reduces sequencing cost while generating higher coverage by
allowing biomedical researchers to focus on specific loci of interest, such as exons. Targeted capture also has the
potential to facilitate the generation of genomic data from DNA collected via saliva or buccal cells. DNA samples...
Full Text:
Open Access
Exome capture from saliva produces high quality
genomic and metagenomic data
JeffreyM
BACKGROUND: Targeted capture of genomic regions reduces sequencing cost while generating higher coverage by
allowing biomedical researchers to focus on specific loci of interest, such as exons. Targeted capture also has the
potential to facilitate the generation of genomic data from DNA collected via saliva or buccal cells. DNA samples...
BACKGROUND: Targeted capture of genomic regions reduces sequencing cost while generating higher coverage by
allowing biomedical researchers to focus on specific loci of interest, such as exons. Targeted capture also has the
potential to facilitate the generation of genomic data from DNA collected via saliva or buccal cells. DNA samples...
Full Text:
JeffreyM. Kidd1,2,*, Thomas J. Sharpton3,4*, Dean Bobo5, Paul J. Norman6, Alicia R.
Martin1, Meredith L
BACKGROUND: Targeted capture of genomic regions reduces sequencing cost while generating higher coverage by
allowing biomedical researchers to focus on specific loci of interest, such as exons. Targeted capture also has the
potential to facilitate the generation of genomic data from DNA collected via saliva or buccal cells. DNA samples...
It is difficult to relate intrinsic nanomaterial properties to their functional behavior in the environment. Unlike frameworks for dissolved organic chemicals, there are few frameworks comparing multiple and inter-related properties of engineered nanomaterials (ENMs) to their fate, exposure, and hazard in environmental systems. We developed and evaluated reproducibility and inter-correlation...
Over the last two decades, satisfiability and satisfiability-modulo theory (SAT/SMT) solvers have grown powerful enough to be general purpose reasoning engines throughout software engineering and computer science. However, most practical use cases of SAT/SMT solvers require not just solving a single SAT/SMT problem, but solving sets of related SAT/SMT problems....
During the past two decades a wide range of intervention programs have emerged in response to escalating concerns over school bullying. The advent of such programs seems justified as 70 percent of school-aged children and youth identify bullying as a problem in their school (Polanin, et al., 2012; Renshaw &...
A mechanistic based critical heat flux (CHF) correlation has been developed derived from a mass, momentum, and energy balance at a nucleation site for water. The trigger mechanism for the CHF condition is postulated to be related to the maximum boiling frequency on a heated surface. It is observed that...
DNA methylation is common in prokaryotes and eukaryotes and has been implicated in various biological roles including gene silencing, X-chromosome inactivation, and genomic imprinting. 5-methylcytosine the "fifth base" of the genetic code comprises 1-3% of the human genome and is primarily found on cytosines within the context of the CpG...