Traffic exhaust is an important source of air pollution. This exposure assessment study examined traffic related air pollution in Curitiba, Brazil, and is particularly relevant due to 75% of the population using diesel public transportation. Traffic density was tabulated, and vehicle-type was distinguished based on their fuel type (diesel or...
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MollyKile, Committee Member, representing College of Public Health and Human Sciences
Harney County contains defining characteristics of regions containing arsenic within the groundwater such as its location in the western United States, unique closed basin geography, complex geology, and seasonal groundwater level fluctuations. Confirmation of arsenic concentrations above the Maximum Contaminant Level Drinking Water Standard of 10 μg/L has been observed...
The COVID-19 pandemic significantly impacted family dynamics, specifically with mothers experiencing unique stressors and challenges. This study explored the association between mothers' anxiety induced by the COVID-19 pandemic and their children’s executive function outcome during preschool. A quantitative approach was used with a sample of 219 families in Oregon, utilizing...
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Molly L. Kile, Committee Member, representing the College of Public Health and Human Sciences
Pasteurization is an effective method of reducing risks associated with foodborne pathogens in raw milk. Cheese made from raw milk has a higher potential to harbor harmful bacterial pathogens. However, some cheesemakers prefer to use unpasteurized milk to preserve the natural microflora present in the raw milk and to prevent...
Throughout their lifetime individuals are exposed to complex mixtures of chemicals. The study of chemical mixtures is an internationally recognized research priority, but seemingly complex challenge. To reduce the intricacy of studying mixtures, researchers have identified different prioritization methods based on exposure or the toxicity of chemicals. However, understanding the...
This dissertation presents a different approach to understanding how amphibians are responding to disease through ontogeny. Although numerous efforts have been conducted to understand host responses to the fungus Batrachochytrium dendrobatidis (Bd), studies have been restricted to distinct developmental stages. This dissertation provides information on host response to Bd across...
Multiple drug resistance (MDR) Tuberculosis (TB), leads to increased use of “second-line” drugs; one of the most effective is ethionamide (ETA). ETA is a prodrug metabolized by a mycobacterial flavin-containing monooxygenase (EtaA) as well human flavin-containing monooxygenases (FMOs). Of the five functional FMOs of humans, FMOs 1, 2, and 3...
Many studies addressing the toxicity of silver nanomaterials have found that smaller sized silver nanoparticles are usually more toxic to organisms and in cell culture than particles of larger sizes yet it is not entirely clear why. We investigated the size dependent toxicity of silver nanoparticles by measuring the response...
Exposure assessment is necessary to determine the frequency and magnitude of environmental contaminants, especially since exposure may lead to adverse health outcomes. Traditional personal exposure assessment tools such as biological samples are limited in their ability to capture a wide range of chemical exposures from a single sample, and others...
Polycyclic aromatic hydrocarbons (PAHs) are widespread environmental contaminants that occur in complex mixtures. These environmental mixtures can consist of both parent PAHs and their derivatives. Several parent PAHs are known or suspected mutagens and/or carcinogens, and a handful of PAH derivatives are known to be more potent mutagens and/or carcinogens...