Toxoplasma gondii, the most common parasitic infection of human brain and eye, persists across lifetimes, can progressively damage sight, and is currently incurable. New, curative medicines are needed urgently. Herein, we develop novel models to facilitate drug development: EGS strain T. gondii forms cysts in vitro that induce oocysts in...
Full Text:
, EricKim
8
, Laura Fraczek
2
, Joseph Lykins
2
, Farida Esaa
2
, Fatima Alibana-Clouser
2
Toxoplasma gondii, the most common parasitic infection of human brain and eye, persists across lifetimes, can progressively damage sight, and is currently incurable. New, curative medicines are needed urgently. Herein, we develop novel models to facilitate drug development: EGS strain T. gondii forms cysts in vitro that induce oocysts in...
Full Text:
, EricKim
8
, Laura Fraczek
2
, Joseph Lykins
2
, Farida Esaa
2
, Fatima Alibana-Clouser
2
Toxoplasma gondii, the most common parasitic infection of human brain and eye, persists across lifetimes, can progressively damage sight, and is currently incurable. New, curative medicines are needed urgently. Herein, we develop novel models to facilitate drug development: EGS strain T. gondii forms cysts in vitro that induce oocysts in...
Full Text:
, Tatiana Santos11, Stuart Woods12,
Patty Lee8, David Donkin8, Eric Kim8, Laura Fraczek2, Joseph Lykins2
Toxoplasma gondii, the most common parasitic infection of human brain and eye, persists across lifetimes, can progressively damage sight, and is currently incurable. New, curative medicines are needed urgently. Herein, we develop novel models to facilitate drug development: EGS strain T. gondii forms cysts in vitro that induce oocysts in...
A complex superposition of locally forced and shoaling remotely generated semidiurnal internal tides occurs on the Oregon continental slope. Presented here are observations from a zonal line of five profiling moorings deployed across the continental slope from 500 to 3000 m, a 24-h expendable current profiler (XCP) survey, and five...
Observations of breaking internal tides on the Oregon continental slope during a 40-day deployment of 5 moorings along 43°12'N are presented. Remotely generated internal tides shoal onto the slope, steepen, break, and form turbulent bores that propagate upslope independently of the internal tide. A high-resolution snapshot of a single bore...
The linear transfer of tidal energy from large to small scales is quantified for small tidal excursion over a near-critical continental slope. A theoretical framework for low-wavenumber energy transfer is derived from “flat bottom” vertical modes and evaluated with observations from the Oregon continental slope. To better understand the observations,...
We quantified the juvenile rearing and migratory patterns of individuals from a population of fall-spawning Chinook salmon Oncorhynchus tshawytscha in Oregon's Salmon River estuary using otolith microchemistry and microstructure. The study confirmed the daily periodicity of otolith growth increments in a natural fish population under field conditions and validated fundamental...
Colloidal lead selenide nanoparticles (PbSe NPs) were synthesized using a microwave-assisted continuous flow reactor. Rapid heating of precursors was performed in the microwave reaction zone to initiate nucleation and was followed by an oil bath growth zone. In this study we have evaluated the effect of the nucleation temperature on...
The network comprising 61 high-frequency radar systems along the U.S. West Coast (USWC) provides a unique, high resolution, and broad scale view of ocean surface circulation. Subinertial alongshore surface currents show poleward propagating signals with phase speeds of O(10) and O(100–300) km d⁻¹ that are consistent with historical in situ...