A long running problem in mathematical biology is the prediction of extinction events, a specialized case of the larger global stability problem found in differential equations and dynamical systems theory. A central technical question is how to introduce the randomness observed in real ecological systems not accounted for in deterministic...
Microbial ecology has been transformed by metagenomics, the study of the genetic in-formation in entire communities of organisms. In the following we develop metagenomic tools arising from the classic Wasserstein metric as applied to questions regarding the diversity between microbial communities. We provide a novel proof of the characteriza-tion of...
Coded metrics that compare representations of structures within the human body to evaluate their similarity are considered useful for planning radiation therapy on cancer targets. However, existing metrics fail to take into account the dose of radiation that will be received by both the target, and surrounding non-target tissue, during...
As the frequency and intensity of wildfires continue to occur in the West, so does the need for measures intended to improve firefighter safety; public safety; and the protection of property, resources, and wildlife. Furthermore, as human activity in the expanding Wildland Urban Interface increases, so does the need for...
The focus of this thesis is to design, characterize, and apply novel computational methods and molecular systems to interrogate heterogeneous human gut microbiome-related phenomena. In Chapter 2, I design, implement, and characterize a method for embedding co-occurrence patterns derived from massive 16s amplicon datasets. I use this method to 1....
Boreal and temperate biomes host nearly half of the earth’s forested ecosystems. The temperate rainforests of the Pacific coast of North America constitute nearly half of all temperate rainforests on earth. Along the northern extent of this region, the perhumid and sub-polar rainforests of southeast and southcentral Alaska are among...
There is a growing body of research that describes the benefits of place-based environmental education (EE) within the schools, including improved competencies, better interpersonal skills, decreased gaps in social divides, increased pupil engagement in learning, increased community awareness, and increased environmental stewardship. Though the benefits are many, few schools utilize...
Gut-brain communication consists of bidirectional routes between cognitive centers of the brain and peripheral intestines. This bidirectional communication is the result of the interplay between enteroendocrine cells (EECs), enteric nervous system, central nervous system, the vagus nerve, and our microbiota. Multiple studies have associated gut microbial dysbiosis with neurological disorders...
New delivery methods for radiotracers are constantly being proposed. Two key properties of the delivery method must be analyzed: dose to patient and effectiveness of delivery. In this work, the localized skin dose for intranasal administration of 18F was determined utilizing MCNP code. An anatomically accurate nasal cavity was constructed...
Natural landscapes around the world have experienced serious loss and degradation, which negatively impacts ecosystem service provision by these landscapes. As a result, there have been serious investments to restore natural capital. However, restoration faces complex trade-offs, such as that between restoration quality, or how closely the restored landscapes resembles...