RAS and Rho small GTPases are key molecular switches that control cell dynamics, cell
growth and tissue development through their distinct signaling pathways. While much has been
learnt about their individual functions in both cell and animal models, the physiological and
pathophysiological consequences of their signaling crosstalk in multi-cellular context...
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tumorigenesis in transgenic zebrafish models
Ti Weng Chew
1,2
, Xing Jun Liu
3
, LihuiLiu
1
, Jan M
RAS and Rho small GTPases are key molecular switches that control cell dynamics, cell
growth and tissue development through their distinct signaling pathways. While much has been
learnt about their individual functions in both cell and animal models, the physiological and
pathophysiological consequences of their signaling crosstalk in multi-cellular context...
RAS and Rho small GTPases are key molecular switches that control cell dynamics, cell
growth and tissue development through their distinct signaling pathways. While much has been
learnt about their individual functions in both cell and animal models, the physiological and
pathophysiological consequences of their signaling crosstalk in multi-cellular context...
RAS and Rho small GTPases are key molecular switches that control cell dynamics, cell
growth and tissue development through their distinct signaling pathways. While much has been
learnt about their individual functions in both cell and animal models, the physiological and
pathophysiological consequences of their signaling crosstalk in multi-cellular context...
RAS and Rho small GTPases are key molecular switches that control cell dynamics, cell
growth and tissue development through their distinct signaling pathways. While much has been
learnt about their individual functions in both cell and animal models, the physiological and
pathophysiological consequences of their signaling crosstalk in multi-cellular context...
RAS and Rho small GTPases are key molecular switches that control cell dynamics, cell
growth and tissue development through their distinct signaling pathways. While much has been
learnt about their individual functions in both cell and animal models, the physiological and
pathophysiological consequences of their signaling crosstalk in multi-cellular context...
RAS and Rho small GTPases are key molecular switches that control cell dynamics, cell
growth and tissue development through their distinct signaling pathways. While much has been
learnt about their individual functions in both cell and animal models, the physiological and
pathophysiological consequences of their signaling crosstalk in multi-cellular context...
RAS and Rho small GTPases are key molecular switches that control cell dynamics, cell
growth and tissue development through their distinct signaling pathways. While much has been
learnt about their individual functions in both cell and animal models, the physiological and
pathophysiological consequences of their signaling crosstalk in multi-cellular context...
RAS and Rho small GTPases are key molecular switches that control cell dynamics, cell
growth and tissue development through their distinct signaling pathways. While much has been
learnt about their individual functions in both cell and animal models, the physiological and
pathophysiological consequences of their signaling crosstalk in multi-cellular context...
Pancreatic beta cells produce and release insulin, a vital hormone that regulates blood glucose levels, and their dysfunction contributes to the development of diabetes mellitus. Dietary zinc deficiency and exposure to the toxicant inorganic arsenic have both independently been associated with diabetes, although the effects of their combination on pancreatic...