Osteosarcoma (OSA) is a primary malignant bone tumor sarcoma that occurs in dogs as well as people and has aggressive biologic behavior with devastating consequences. Because of the similarities in morphology and prognosis, OSA in dogs represents an effective model for the equivalent disease in humans. Mesenchymal stem cells (MSCs)...
The development of problem-solving behaviors in canines, including persistence, has implications for canine training, welfare, and the human-dog bond. Past research has shown that a variety of factors, including genetics (domestication) and training experience, play a role in a how a canine might behave during a problem-solving task. Less well...
The purpose of this study was to examine the validity and reliability of the 30-minute cycling time trial to estimate the heart rate at lactate threshold. Recreationally trained cyclists and triathletes (n = 47) performed 3 tests in random order: 1) One graded exercise test to directly determine lactate threshold...
PURPOSE: We tested the hypothesis that the unsupervised, isokinetic 3- minute all-out cycling test (3MT) would be a valid and reliable way to determine end power (EP) and work done above end power (WEP). Additionally, we hypothesized that EP would successfully demarcate between heavy and severe-intensity exercise and thus represent...
Maximal aerobic capacity (V̇O₂max) is the most widely used measure for assessing cardiorespiratory fitness. It is a strong contributor to performance in endurance sports, predicts functional capacity in older adults, and is related to overall disease risk. As such, it is important that testing methodologies for determining V̇O₂max provide valid...
Over the past few decades, a primary focus has been on the negative health effects of not participating in regular moderate-to-vigorous physical activity (MPVA). Only recently has sedentary behavior been studied as a distinct and independent risk factor for adverse health outcomes. This dissertation sought to provide new insights into...
Hip fractures have high mortality and morbidity rates after incidence, with osteoporosis being a major risk factor due to the loss of bone mineral density (BMD). Lower-body resistance exercises, such as squats, can provide sufficient loading on the hip to induce osteogenic effects. However, this loading may depend on how...