To characterize the mechanism through which myosin XI-K attaches to its principal endomembrane cargo, a yeast two-hybrid library of Arabidopsis thaliana cDNAs was screened using the myosin cargo binding domain as bait. This screen identified two previously uncharacterized transmembrane proteins (hereinafter myosin binding proteins or MyoB1/2) that share a myosin...
Cervical cancer is the fourth most common cancer in women worldwide with human papillomavirus (HPV) being the main cause the disease. Chromosomal amplifications have been identified as a source of upregulation for cervical cancer driver genes but cannot fully explain increased expression of immune genes in invasive carcinoma. Insight into...
Gene regulatory networks are commonly used for modeling biological processes and revealing underlying molecular mechanisms. The reconstruction of gene regulatory networks from observational data is a challenging task, especially considering the large number of players (e.g. genes) involved and the small number of biological replicates available for analysis. Herein, we...
Given the high pressure in fishing resources, the interest of going beyond the resources and understanding market trends, market barriers, and fisheries value-chain inequities, has increased in the last decade. This knowledge is necessary to improve those chains and to promote better financial returns for fishers and market participants, in...
Coastal communities face heightened risk to coastal flooding and erosion hazards due to sea-level rise, changing storminess patterns, and evolving human development pressures. Incorporating uncertainty associated with both climate change and the range of possible adaptation measures is essential for projecting the evolving exposure to coastal flooding and erosion, as...
This report assesses climate change impacts and associated community and ecosystem vulnerability. It was compiled by a group of Oregon State University researchers and students, outreach specialists, and coastal community members in Tillamook County, Oregon (OR). Through sustained engagement with the Tillamook County Coastal Futures Knowledge to Action Network (TCCF...
Coastal communities are increasingly experiencing climate change–induced coastal disasters and chronic flooding and erosion. Decision makers and the public alike are struggling to reconcile the lack of ‘‘fit’’ between a rapidly changing environment and relatively rigid governance structures. In efforts to bridge this environment-governance gap in Tillamook County, Oregon, stakeholders...
Coupled models of coastal hazards, ecosystems, socioeconomics, and landscape management in conjunction with alternative scenario analysis provide tools that can allow decision-makers to explore effects of policy decisions under uncertain futures. Here, we describe the development and assessment of a set of model-based alternative future scenarios examining climate and population...
Deciding which textbook to assign to students is often a very difficult decision. A textbook should offer more than just a synthesis of information, it should inspire curiosity, cause one to reflect, and provide a framework for making decisions. Most reviews reflect a single opinion, sometimes based on personal preferences....
The Plant Ontology (PO;http://www.plantontology.org/" is a publicly available, collaborative effort to develop and maintain a controlled, structured vocabulary ('ontology') of terms to describe plant anatomy, morphology and the stages of plant development. The goals of the PO are to link (annotate) gene expression and phenotype data to plant structures and...