Targeting the epigenome, including the use of histone deacetylase (HDAC) inhibitors, is a novel strategy for cancer chemoprevention. Sulforaphane (SFN), a compound found at high levels in broccoli and broccoli sprouts, is a potent inducer of Phase 2 detoxification enzymes and inhibits tumorigenesis in animal models. SFN also has a...
L. C. Dunn (1893-1974) spent most of his scientific career conducting research in
developmental genetics as a member of the Zoology Department at Columbia
University in the City of New York. He had an accomplished scientific career
researching mutations in mice, which earned him respect from other geneticists and
scientists....
Metabolic syndrome (MetS) and abdominal obesity (AbOb) increase the risk of
developing cardiovascular disease and diabetes. Energy restriction (ER), highprotein
(PRO) intake and high-intensity interval training (HIT) can independently
improve MetS and AbOb. However, ER reduces metabolically active lean body
mass (LBM) in addition to body fat (BF). Purpose: To...
In endurance-trained men, an acute bout of exercise is shown to suppress post-exercise appetite and alter changes in specific appetite regulating hormones. Limited research has examined these responses in endurance-trained women. PURPOSE: To investigate the effect of exercise intensity on the appetite regulating hormones acylated ghrelin, PYY and GLP-1 and...
Linus Pauling incorporated hemoglobin and a disease of the blood, sickle cell anemia, into many of his researches between the mid-1930s and mid-1970s. In the early 1930s Pauling became interested in organic chemistry and named hemoglobin as one of the first biochemical substances that he planned to analyze. In 1935...
The present study examined the influence of the
demographic variables of age, gender, major in college, and
level of education or class standing on individuals' stage
of moral development. Trevino's interactionist model,
combined with the basic principles of cognitive moral
development, provided the theoretical basis for this study.
One-hundred and...
Aging, obesity and increased waist circumference (WC) increases risk for metabolic syndrome (MetS). MetS is a cluster of symptoms (elevated WC, triglycerides, blood pressure, fasting glucose, and decreased high-density lipoprotein cholesterol [HDL-C]) increasing risk for chronic disease. Low-energy dense (LED) diets, emphasizing whole food eating patterns, have not been examined...
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Melinda M. Manore
Aging, obesity and increased waist circumference (WC) increases risk for
Purpose: This study examines the nutrition knowledge/behaviors of adolescent athletes before/after a sport nutrition intervention. Methods: The WAVE pilot study intervention provided sport nutrition education to soccer players (n=26; 14-19y) through face-to-face lessons (Intervention group [IG]). Anthropometrics and the Sport Nutrition Questionnaire were done pre/post intervention, while the comparison group...
The prevalence of exercise-induced menstrual dysfunction (ExMD) ranges between 6-79% in endurance-trained women and may result from a low energy availability (EA; kcal/kgFFM/d). EA is the energy remaining after planned exercise, which is available for basic physiological processes and daily living activities. One mechanism for energy conservation may be a...
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Melinda M. Manore
The prevalence of exercise-induced menstrual dysfunction (ExMD) ranges
The purpose of this study is to determine whether a 12-week nutrition and physical activity (PA) intervention program for middle-aged, pre-menopausal women at risk for Metabolic Syndrome (MetS) would reduce their risk factors. Ten overweight women (mean ± SD: age = 47 ± 3y; Body Mass Index = 31.0 ±...
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Melinda M. Manore
The purpose of this study is to determine whether a 12-week nutrition