Described herein is the synthesis of an uncharged stereoregular oligonucleotide
analog consisting of cytosine bases linked at specific intervals to a polyamide backbone
derived from (L)-glutamic acid. Preparation of this analog entailed borane reduction of
(L)- pyroglutamic acid to give optically pure lactam alcohol 9. Tosylation and alkylation
with cytosine...
Many ecosystem services are public goods whose provision depends on the spatial pattern of land use. The pattern of land use is often determined by the decisions of multiple private landowners. Increasing the provision of ecosystem services, while beneficial for society as a whole, may be costly to private landowners....
An ensemble local hydrologic forecast derived from the seasonal forecasts of the International Research Institute for Climate Prediction (IRI) is presented. Three-month seasonal forecasts were used to resample historical meteorological conditions and generate ensemble forcing datasets for a TOPMODEL-based hydrology model. Eleven retrospective forecasts were run at Florida and New...
The trajectory of aquaculture growth in sub-Saharan Africa has necessitated closer attention to the use of environmental best management practices (BMPs). Two BMPs in particular, water reuse and floating feeds, are being promoted for adoption by pond fish farmers in sub-Saharan Africa. In this study, we investigated: (1) the effect...
An integrated model combining a wildlife population simulation model and timber harvest and growth models was developed to explore the tradeoffs between the likelihood of persistence of a hypothetical wildlife species and timber harvest volumes on a landscape in the Central Oregon Cascades. Simulated annealing, a heuristic optimization technique, was...
Disease transmission forecasts can help minimize
human and domestic animal health risks by indicating
where disease control and prevention efforts should be
focused. For disease systems in which weather-related
variables affect pathogen proliferation, dispersal, or transmission,
the potential for disease forecasting exists. We
present a seasonal forecast of St. Louis...
Numerical weather prediction models often perform poorly for weakly forced, highly variable winds in nocturnal stable boundary layers (SBLs). When used as input to air-quality and dispersion models, these wind errors can lead to large errors in subsequent plume forecasts. Finer grid resolution and improved model numerics and physics can...
Canopy management is an important aspect of control of powdery mildew diseases and may influence the intensity of fungicide applications required to suppress disease. In hop, powdery mildew (caused by Podosphaera macularis) is most damaging to cones when infection occurs during bloom and the juvenile stages of cone development. Experiments...
Canopy management is an important aspect of control of powdery mildew diseases and may influence the intensity of fungicide applications required to suppress disease. In hop, powdery mildew (caused by Podosphaera macularis) is most damaging to cones when infection occurs during bloom and the juvenile stages of cone development. Experiments...