Shotgun metagenomic DNA sequencing is a widely applicable tool for characterizing the functions that are encoded by microbial communities. Several bioinformatic tools can be used to functionally annotate metagenomes, allowing researchers to draw inferences about the functional potential of the community and to identify putative functional biomarkers. However, little is...
BACKGROUND: Targeted capture of genomic regions reduces sequencing cost while generating higher coverage by
allowing biomedical researchers to focus on specific loci of interest, such as exons. Targeted capture also has the
potential to facilitate the generation of genomic data from DNA collected via saliva or buccal cells. DNA samples...
Full Text:
,
KatherineS Pollard3,12, Jeffrey D Wall12, Carlos D Bustamante1 and Brenna M Henn1,5*
Abstract
Background
BACKGROUND: Targeted capture of genomic regions reduces sequencing cost while generating higher coverage by
allowing biomedical researchers to focus on specific loci of interest, such as exons. Targeted capture also has the
potential to facilitate the generation of genomic data from DNA collected via saliva or buccal cells. DNA samples...
BACKGROUND: Targeted capture of genomic regions reduces sequencing cost while generating higher coverage by
allowing biomedical researchers to focus on specific loci of interest, such as exons. Targeted capture also has the
potential to facilitate the generation of genomic data from DNA collected via saliva or buccal cells. DNA samples...
Full Text:
. Feldman11,
KatherineS. Pollard3,12, Jeffrey D. Wall12, Carlos D. Bustamante1, Brenna M. Henn1,5
BACKGROUND: Targeted capture of genomic regions reduces sequencing cost while generating higher coverage by
allowing biomedical researchers to focus on specific loci of interest, such as exons. Targeted capture also has the
potential to facilitate the generation of genomic data from DNA collected via saliva or buccal cells. DNA samples...
Microplastics (<5mm diameter) are present in a considerable number of marine and aquatic species. Understanding which species, the global spatial distribution, and what quantities of microplastics are present is extremely important for understanding the potential impacts they could have on recreationally important organisms and for the assessment of risk. We...
Earthquake rupture scenarios are important tools for understanding the nature of plate movement and patterns in seismic activity. The creation and assessment of these rupture scenarios rely heavily on geologic reasoning and principles applied to earthquake event data. This reliance introduces a certain amount of subjectivity to the rupture scenario...
We present a new, non-flux corrected AOGCM, GENMOM, that combines the GENESIS version 3 atmospheric GCM (Global Environmental and Ecological Simulation of Interactive Systems) and MOM2 (Modular Ocean Model version 2) nominally at T31 resolution. We evaluate GENMOM by comparison with reanalysis products (e.g., NCEP2) and three models used in...
Respondent-driven sampling (RDS) is used throughout the world to estimate prevalence and population size for hidden populations. Although RDS is an effective method for enrolling people from key populations in studies, it relies on a partially unknown sampling mechanism, and thus each individual’s inclusion probability is unknown. Current estimators for...