We are developing a flavin-containing (Fmo) knock-out mouse for Fmo2 that will be utilized to elucidate the role of active human FMO isoform 2 (FMO2.1) in xenobiotic metabolism and toxicity. Since FMO2 is primarily expressed in lung this will provide information on how 27% of African-Americans and 5% of Hispanics...
This thesis presents a method for determining range
of body motion for a walking machine with feet fixed on
the ground. The darkling beetle was selected as the
sample subject in this study.
A closed form inverse kinematic solution is used to
determine if a point in space is within...
Simulation models were developed to explore the reversible nature of gecko dry
adhesion system. The central idea of this model is that even with a small moment imparted on the contact tip, the seta can be easily ad-adhered. It is shown that this contact condition is very sensitive, but can...
A digoxigenin-labeled nonradioactive detection system was used
to screen a zebrafish cDNA library for p53-like and ras-like genes.
One clone was isolated and identified as an incomplete p53-like
gene. The insert size of this clone is 1777 bp, which encodes part of
evolutionarily conserved region II and all of regions...
Zebrafish (Brachydanio rerio) are small, freshwater teleost fishes in the family
Cyprinidae, the true minnows. They are native to the tropical latitudes of India, but
have become widespread through their use as aquarium fish and as models for several
branches of biological research. Their ease of rearing, short generation time,...
Managing rangelands with livestock grazing is a tool that can be applied to obtain vegetation management objectives. Animals utilize available resources, which vary in quantity and quality, across the landscape. Their movements are adjusted to the spatial and temporal heterogeneity of resource distribution. Controlling livestock distribution is fundamental to economically...
Fanconi's Anemia (FA) is an autosomal recessive chromosomal instability disorder. The
symptoms include congenital abnormalities, defective hematopoiesis (formation of cells
of the blood), and high risk of developing acute myeloid leukemia and solid tumors.
Fanconi researchers have long been puzzled by how Fanconi Anemia (FA) cells, which
are known to...
BACKGROUND: Consumption of raspberry products have been observed to produce healthful effects and reduce weight gain and positively shift metabolism in mice fed obesigenic diets. In the past, our lab has successfully shown a reduction in weight gain for mice consuming RPC+HF vs. mice fed HF alone. Currently, there is...