One of the important ‘hallmarks’ of cancer is angiogenesis, which is the process of formation of new blood vessels that are necessary for tumor expansion, invasion and metastasis. Under normal physiological conditions, angiogenesis is well balanced and controlled by endogenous proangiogenic factors and antiangiogenic factors. However, factors produced by cancer...
Lifestyle factors are responsible for a considerable portion of cancer incidence worldwide, but credible estimates from the World Health Organization and the International Agency for Research on Cancer (IARC) suggest that the fraction of cancers attributable to toxic environmental exposures is between 7% and 19%. To explore the hypothesis that...
Fusarium crown rot (FCR), caused by and , reduces wheat ( L.) yields in the Pacific Northwest (PNW) of the US by as much as 35%. Resistance to FCR has not yet been discovered in currently grown PNW wheat cultivars. Several significant quantitative trait loci (QTL) for FCR resistance have...
A fully integrated CMOS GPS receiver RF front end optimized for low power operation is presented. The system operates with a supply voltage down to 250 mV. A prototype has been fabricated in a 0.13μm CMOS process and includes a low voltage LNA, quadrature oscillators, and quadrature mixers. It exhibits...
To meet societal needs, modern estuarine science needs to be interdisciplinary and collaborative, combine discovery with hypotheses testing, and be responsive to issues facing both regional and global stakeholders. Such an approach is best conducted with the benefit of data-rich environments, where information from sensors and models is openly accessible...
Stripe rust (Puccinia striiformis f. sp. tritici) has been receiving
increased attention in the USA since the appearance of more virulent races
detected in the past decade. These races caused yield losses even in areas
where the disease previously was rarely detected. Host plant resistance is the
most cost effective...
Wheat (Triticum aestivum L.) is one of the major crops produced in the U.S. Pacific Northwest, a region known for its wheat production for international export. Wheat production in the region is threatened by diseases such as Cephalosporium stripe and stripe rust. Cephalosporium stripe is a vascular wilt disease of...
For several decades, annually recurring blooms of the photosynthetic ciliate Myrionecta rubra have been observed in the Columbia River estuary in late summer. In an effort to understand the dynamics of these blooms, we investigated the genetic variability of M. rubra and its cryptophyte plastids within 3 large estuarine blooms...
Although IL-4 is a well-characterized multi-functional cytokine, its role as a survival factor in T cells is not completely understood. In an attempt to uncover IL-4-mediated survival, we studied caspase activation in primary mouse T lymphocytes undergoing death by neglect, activation-induced or steroid-induced cell death. Here, we identify the executioner...
The fungitoxicity of acetone extracts from the xylem of Fusarium
wilt disease resistant tomato plants (cv. Jefferson) inoculated with Fusarium
oxysporum f. sp. lycopersici was greatly influenced by environmental
factors. Extracts obtained from plants 1 h after watering were 4-times
more toxic than extracts from plants subjected to water stress...