Previous studies have indicated that staphylococci have potential for use as indicators of water quality in swimming pool and other recreational waters. However, these organisms are not yet included in the official guidelines for recreational water quality promulgated by health authorities. The purpose of this study is to determine water...
Proper immune function is indispensable, as failure to mount an immune response against a pathogen can lead to serious complications or even death. T cells act by enhancing the activation of phagocytic cells as well as the activation of B cells. Their widespread influence on an immune response makes optimal...
With the growth of Internet technologies, online-based foreign language curricula are being introduced at large numbers of institutions internationally. This peer-reviewed volume, geared towards a broad audience, presents innovative research on online language teaching, with chapters by highly engaged scholars and practitioners from the U.S. and Europe, with a strong...
Fungi in the genus Tolypocladium are diverse in their host associations, but the predominant ecologies include parasites of the ectomycorrhizal genus Elaphomyces and pathogens of insects. The aim of this dissertation research is to examine the evolution of these fungi and their host associations. To accomplish this several lines of...
Altogether, this dissertation highlights the value of mass spectrometry-based analysis of intact proteins for solving problems related to understanding disease mechanisms and developing new therapeutics.
Mutations to the antioxidant enzyme Cu, Zn Superoxide Dismutase (SOD1) perturb protein structure in vivo to cause 2-5% of amyotrophic lateral sclerosis (ALS) cases. Metal-deficient...
An integral component to understanding lithospheric rheology, fault mechanics, and geodynamic processes is knowledge of the subsurface thermal regime. This study presents thermal data from 26 new borehole sites drilled during the installation of borehole strain meters as part of the Plate Boundary Observatory (PBO). These data extends existing coverage...
To examine the macrophage response to M. avium, I compared inflammasome and cytosolic sensor expression and activation. My result demonstrated that virulent strains of M. avium (A5 and 104) suppress IL-1β production and induce IFN-β production in macrophages. M. avium mutants deficient at DNA export in the biofilm exhibited reduced...
This thesis aims to explore the effects of organizational and management principles within the context of a student club – an international Formula Student team. Research on the effects of organizational structuring on student club performance tends to be qualitative in nature. While considering the inherent complexity of the human...