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  • Blood Processing Technologies for Cryopreserved Transfusion Products and Extracorporeal Treatment Applications

    Creator:
    Lahmann, John M.
    Abstract:
    There is a significant need for technological advancement in blood processing. New technologies in rapid processing of frozen blood products could significantly improve management of the blood supply chain in the United States by enabling on-demand use of frozen blood products that can be stored for 10 years instead of...
    Resource Type:
    Dissertation
    Full Text:
    4 and Dr. Kate Schilke assisted with the coating strategy. Jolynn Meza Wynkoop assisted with the

  • Demonstration of an Alginate Valve in a Paper Microfluidic Device

    Creator:
    Cornwell, David Q.
    Abstract:
    Paper microfluidic devices are capable of processing fluids using capillary flow in materials that are lower cost than the standard materials used in microfluidics. Due to the low cost of their fabrication and minimal requirements for instrumentation, paper microfluidic devices are ideal for use in low-resource settings. They have the...
    Resource Type:
    Honors College Thesis
    Full Text:
    _____________________________________________________________________ Kate Schilke, Committee Member, representing Bioengineering

  • Signal Enhancement in Lateral Flow Tests for Infant HIV Diagnosis

    Creator:
    Rodriguez, Michael A.
    Abstract:
    Paper-based assays for HIV diagnosis are cheap, portable, and require little to no skilled training, electricity, or expensive equipment to perform successfully. However, there is a need for tests with lower limits of detection (LOD) for diagnosing infection at the earliest stages. Effective labeling to increase signal-to-noise ratio is critical...
    Resource Type:
    Masters Thesis

  • The Effect of Oxygen and Salinity Conditions on Soluble Metabolic Product Formation by Methylomicrobium buryatense 5GB1

    Creator:
    Cameron, Marina R.
    Abstract:
    Methanotrophic bacteria are promising means of producing value-added products as they have the ability to transform methane under atmospheric temperature and pressure. Efforts to develop methanotrophs to produce value-added products are hoped to incentivize a decrease in methane flaring operations. The data collected during this study was used to inform...
    Resource Type:
    Masters Thesis
    Full Text:
    . Besides my advisor, I would like to thank the rest of my thesis committee: Mark Dolan, Kate Schilke

  • Retention of protein repulsive character and antimicrobial activity of PEO brush layers following nisin entrapment

    Creator:
    Auxier, Julie A.
    Abstract:
    Nisin, an amphiphilic, antimicrobial peptide, has been shown to integrate into the hydrophobic inner region of poly(ethylene oxide) (PEO) brush layers; however, the presence of integrated nisin may compromise the protein repulsive character of the PEO layer. In particular, the introduction of fibrinogen to nisin-loaded brush layers has been observed...
    Resource Type:
    Masters Thesis
    Full Text:
    A. Auxier, Justen K. Dill, Karl F. Schilke, Joseph McGuire * School of Chemical, Biological

  • Quantifying nisin adsorption behavior at pendant polyethylene oxide brush layers

    Creator:
    Dill, Justen K.
    Abstract:
    A more quantitative understanding of peptide loading and release from polyethylene oxide (PEO) brush layers will provide direction for development of new strategies for drug storage and delivery. The antimicrobial peptide nisin shows potent activity against Gram-positive bacteria including the most prevalent implant-associated pathogens, its mechanism of action minimizes the...
    Resource Type:
    Masters Thesis
    Full Text:
    be learned in a laboratory. My sincere appreciation goes out to Dr. Karl Schilke who was absolutely

  • Mathematical and Experimental Approaches for Designing Less Toxic Cryopreservation Methods

    Creator:
    Warner, Ross M.
    Abstract:
    Successful cryopreservation of all biological specimens would have an untold positive impact on medicine and scientific research. However, cryopreservation of the most complex biological specimens, such as tissues and organs, remains elusive. Vitrification, or ice-free cryopreservation, is promising for cryopreservation of complex specimens. The biggest challenge, though, is the toxicity...
    Resource Type:
    Dissertation
    Full Text:
    members: Dr. Joe Baio, Dr. Kate Schilke, Dr. Brian Wood, and Dr. Frank Chaplen. My discussions with Dr

  • Optical Sensors using Biological Photonic Crystals

    Creator:
    Squire, Kenneth James
    Abstract:
    This dissertation focuses on the application of diatom frustules, the biosilica shell of an algae possessing physical and photonic properties capable of enhancing optical signals, for the enhancement of optical sensing. In this work, we incorporate diatom frustules into biosensors for signal enhancement and improved target molecule detection. The potential...
    Resource Type:
    Dissertation
    Full Text:
    domains (b, d).Classification results of training (e) and test dataset (f) plotted with respect to the

  • Computing Resource Usage as a Factor of Student Success

    Creator:
    Moissinac, Béatrice
    Abstract:
    Learning Analytics and other branches of Educational Research such as Computing Education Research (CER) implicitly assume that students, especially college students, have no barriers to access learning platforms or software packages. This assumption may be attributed to such pervasive beliefs such as "everyone has a device", or "everyone can access...
    Resource Type:
    Dissertation

  • Multi-Technique Characterizations of Natural and Biomimetic Adhesives

    Creator:
    Fowler, James E.
    Abstract:
    There have been many attempts to characterize and mimic natural fluid-based adhesive systems. However, very few of these studies have examined surface or interfacial interactions between adhesive and substrate. Furthermore, until now no study has used a combination of surface analytical and kinematic techniques to determine the precise chemical mechanisms...
    Resource Type:
    Dissertation
    Full Text:
    ., Sampalla, B., Rupp, F., Boley, M. & Schmitt, C. 2017 Adhesion and friction of the smooth attachment