Several compounds have been recently identified which are effective against dengue virus, a tropical arbovirus highly prevalent in southeast Asia and central America. Initial intrinsic fluorescence characterization of the mechanism of action of compound B reveals binding affinity to the dengue capsid protein. A molecular beacon unwinding assay and malachite...
The ability to focus light through strongly scattering materials is opening up exciting new avenues in many fields, such as optics, computer vision, biology, and medicine, which utilize light delivery and imaging techniques. Efficient, high resolution wavefront shaping and optimization methods are crucial to enabling this new capability.
In this...
This thesis presents the results of quantum-mechanical first principles calculations
of optical, electronic and mechanical properties of organic molecules and solids, which have
diverse potential applications such as photovoltaics, flexible electronics, and mechanical
catalysts with applications in force sensors and self-healing materials.
The electronic and optoelectronic properties of organic thin...
Crystals are solid materials with periodic and symmetric molecular patterns. The structure of a crystalline solid determines its properties, making it essential to study its structures. From the principle of minimum energy, a crystal will choose a structure with the lowest free energy F = U – TS. At low...
The behavior of small atomics cluster largely depends on their geometry,
due to the high ratio of surface atoms to interior atoms. One interesting aspect
to study clusters centers around characterizing the transition behavior between
nite and bulk materials, where the ratio of surface atoms to interior atoms is
very...
Mixed anion compounds that form ZrCuSiAs-type crystal structures exhibit remarkable properties such as superconductivity at low temperatures,
hole conduction with optical transparency in the visible region, and exciton absorption at room temperature. In this thesis, properties of a selected group of materials out of the very large set of mixed...
The common choice in computational approximations, from 0 K to room temperature, of solid materials is to assume the structure remains unchanged at low temperatures. Often such an approximation is a very reasonable assumption. However, this approximation is not absolute and can break down even for relatively simple materials such...
Strategic planning for forests subjected to multiple uses is important for management that sustains and balances these many uses. In the wildland urban interface where forests are in the backyards of members of the public who avidly recreate in them, it is also important to include the community in the...
The purpose of this study was to determine the effects of long-term weighted vest
exercise on hip bone mass, functional ability and static balance in elderly women. This was
a within subject exercise intervention study and included a 6-month control period.
Twenty-three subjects (age 85 ± 6) were recruited and...
To examine the potential for exercise to build bone mass during growth, objectives of this dissertation included: 1) determine the effects of 7 months of jumping followed by 7 months of detraining on hip and spine bone mass in the prepubertal children; 2) determine variables that best predict bone mineral...