OBJECTIVE: The associations of some risk factors with cardiovascular disease (CVD) are attenuated in
older age; whereas others appear robust. The present study aimed to compare CVD risk factors across
older age. METHODS: Participants (n = 4883) in the Cardiovascular Health Study free of prevalent CVD,
were stratified into three...
Full Text:
Health Study
Michelle C. Odden a, *, Michael G. Shlipak b, c, Heather E. Whitson d, e, Ronit Katz f
OBJECTIVE: The associations of some risk factors with cardiovascular disease (CVD) are attenuated in
older age; whereas others appear robust. The present study aimed to compare CVD risk factors across
older age. METHODS: Participants (n = 4883) in the Cardiovascular Health Study free of prevalent CVD,
were stratified into three...
Recent evidence has demonstrated the importance of kidney function in healthy aging. We examined the association between kidney function and change in cognitive function in 3,907 participants in the Cardiovascular Health Study, recruited from 4 U.S. communities, and studied from 1992 - 1999. Kidney function was measured by cystatin C-based...
Background—The effect of intensive blood pressure (BP) lowering on kidney function among individuals with established cerebrovascular disease and preserved estimated glomerular filtration rate (eGFR) is not established.
Methods and Results—Among 2610 participants randomized to a lower (<130 mm Hg) versus higher (130–149 mm Hg) systolic BP target with repeated measures...
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. McClure, PhD; Rebecca Scherzer, PhD;
Michelle C. Odden, PhD; Carole L. White, PhD, RN; MichaelShlipak
Background—The effect of intensive blood pressure (BP) lowering on kidney function among individuals with established cerebrovascular disease and preserved estimated glomerular filtration rate (eGFR) is not established.
Methods and Results—Among 2610 participants randomized to a lower (<130 mm Hg) versus higher (130–149 mm Hg) systolic BP target with repeated measures...
Background—The effect of intensive blood pressure (BP) lowering on kidney function among individuals with established cerebrovascular disease and preserved estimated glomerular filtration rate (eGFR) is not established.
Methods and Results—Among 2610 participants randomized to a lower (<130 mm Hg) versus higher (130–149 mm Hg) systolic BP target with repeated measures...
Objectives:
To examine the association between kidney function and all-cause mortality in octogenarians.
Design
Retrospective analysis of prospectively collected data.
Setting:
Community.
Participants:
Serum creatinine and cystatin C were measured in 1,053 Cardiovascular Health Study (CHS) All Stars participants.
Measurements:
Estimated glomerular filtration rate (eGFR) was determined using the Chronic...
Purpose: To determine if the associations among established risk factors and reduced kidney function vary by age.
Methods: We pooled cross-sectional data from 14,788 nondiabetics aged 40 to 100 years in 4 studies: Cardiovascular Health Study, Health, Aging, and Body Composition Study, Multi-Ethnic Study of Atherosclerosis, and Prevention of Renal...
OBJECTIVE: The associations of some risk factors with cardiovascular disease (CVD) are attenuated in
older age; whereas others appear robust. The present study aimed to compare CVD risk factors across
older age. METHODS: Participants (n = 4883) in the Cardiovascular Health Study free of prevalent CVD,
were stratified into three...
BACKGROUND: Chronic kidney disease (CKD) and hyperuricemia often coexist and both conditions are increasing in prevalence in the U.S., although their shared role on cardiovascular risk remains highly debated.
STUDY DESIGN: Cross-sectional and longitudinal
SETTING AND PARTICIPANTS: Participants in the National Health and Nutrition Examination Survey (NHANES) from 1988 to...