An Automated Star Tracking System was designed and built for an undergraduate senior design project. The system was designed as a portable and easy to use means of tracking celestial objects, and is usable for a variety of both personal and professional purposes. The project was built around exploring the...
America is said to be the land of the free and the home of the brave. With the unfair treatment of people of color in this country, however, one would believe that somewhere in the fine print, they were excluded from that phrase. The very foundation of this country was...
The focus of this dissertation was to understand protein function and structure ona molecular level. To do this successfully, a variety of biochemical and biophysicaltechniques were employed. A wide variety of techniques were applied to study theproteins of interest in this dissertation to probe protein-protein interactions, proteinfunction, protein structure, and...
Congenital hearing loss is a common disorder and over 60 mutations in the sensory hair cell protein, otoferlin, have been linked to pre-lingual deafness. Although otoferlin is essential for hearing, the large size and low solubility of the protein have limited approaches to study its function on a molecular-level. To...
Otoferlin is a C2-domain, transmembrane protein whose mutated form is responsible for the DFNB9 subtype of prelingual hearing impairment. Mutations in otoferlin cause an autosomal recessive, non-syndromic form of deafness that is characterized by auditory neuropathy/ auditory dissynchrony (AN/AD), meaning that the outer hair cells (OHCs) are normal, and the...
We modeled surface wetness at high resolution, using a dynamic hydrology model, to predict flood and
swamp water mosquito abundances. Historical meteorologic data, as well as topographic, soil, and vegetation
data, were used to model surface wetness and identify potential fresh and swamp water breeding habitats
in two northern New...
The purpose of this study was to investigate the initial on-site supervision experience of school counseling interns. Current counseling supervision research has failed to address dynamics specific to the context of school counselor training and professional development. This gap in the research suggest that examining the phenomenological experience of what...
This is a case study of the cooperative development of an ocean condition forecasting tool by Oregon commercial fishermen, Oregon State University (OSU) scientists, and OSU student software engineers. Ocean condition forecasting models developed by OSU scientists were used to create an online tool to assist decision-making for fishermen. This...
Engineering is largely concerned with models and modelling. Models provide a context in which decisions are made. Here the modelling process is considered in a general sense and then the relationship with engineering models is developed. For understanding, a first step is to differentiate and categorize. Thus ten types of...
In this dissertation, excited state proton transfer (ESPT) and its inhibition in solution and protein environments are revealed using both femtosecond transient absorption (fs-TA) spectroscopy and femtosecond stimulated Raman spectroscopy (FSRS). Using a tunable Raman pump to enhance transient vibrational features of the photoacidic chromophore HPTS in methanol and methanol...