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  • Possible Autocrine/Paracrine Action of Progesterone in the Ovine Corpus Luteum

    Creator:
    Smallman, Mary A.
    Abstract:
    The objective of the present research was to determine, by use of the progesterone receptor antagonist RU-486, whether progesterone by autocrine/paracrine action suppresses phosphatidylinositol hydrolysis, and thus, the production of prostaglandin F2a during the midluteal phase of the estrous cycle in ewes. Two experiments were performed. Experiment 1 consisted of...
    Resource Type:
    Masters Thesis
    Full Text:
    approved: ______________________________________________________ Fredrick Stormshak The

  • Role of hypothalamic biogenic amines in the release of luteinizing hormone in the ewe

    Creator:
    Wheaton, Jonathan Edward
    Abstract:
    The role of hypothalamic biogenic amines (norepinephrine, dopamine and serotonin) in regulating the release of luteinizing hormone (LH) in the ewe was investigated. Eleven experiments utilizing mature crossbred or Hampshire ewes were conducted to determine the ability of exogenous 17β-estradiol and various pharmacological agents to alter the levels of hypothalamic...
    Resource Type:
    Dissertation
    Full Text:
    Abstract approved: Redacted for privacy Fredrick Stormshak The role of hypothalamic biogenic amines

  • Nongenomic Actions of Steroid Hormones in the Ovine Endometrium

    Creator:
    Ireton, Kyle E.
    Abstract:
    The steroid hormone estrogen plays a crucial role in regulating certain mammalian tissues, especially female reproductive systems. Estrogen effects physiological changes in the cell by altering transcription activity for certain target genes, as a consequence of interactions between estradiol-17β (E2) and its nuclear receptor (nER). This mechanism of cellular control...
    Resource Type:
    Honors College Thesis
    Full Text:
    :____________________________________________________________ Dr. Fredrick Stormshak The