While there are many ways to evaluate a user interface design, the user's mental workload and situation awareness (SA) are particularly important considerations in the supervisory control of safety-critical systems. Typically, operators of these systems must monitor high-volume, time-sensitive status information. Interface design for this domain can be challenging and...
The computer game industry continues to progress toward realistic-looking character motion. However, even in state-of-the-art games, the use of motion capture data in character animation may result in errors such as “foot slipping,” where the feet do not match up with the floor properly during translation. Various algorithms have been...
All nuclear reactors rely heavily on the use of level sensing instrumentation to detect the behaviour of liquid in vessels. The majority of level sensing instruments are differential pressure sensing meters, which are invasive and could be the failure source in the pressure boundary of the primary coolant system. In...
Self-Monitoring scores were significantly influenced by the social context that respondents considered while completing it. Normal distributions were generated within testing conditions. Bimodal distributions were generally found across testing conditions and within a no context specified condition, suggesting item ambiguity might be leading to the scale’s class variable interpretation.
In 1988 the Tualatin River was designated 'water quality limited' by the Oregon Department of Environmental Quality. Three sources of pollution: urban point source, forestry non-point source and agricultural non-point source pollution were considered to contribute unacceptable levels of nutrients (phosphates and ammonium nitrates) to the river. Since a significant...
We have recently reported that cell-penetrating peptides (CPPs) and novel chimeric peptides containing CPP (referred as
B peptide) and muscle-targeting peptide (referred as MSP) motifs significantly improve the systemic exon-skipping activity
of morpholino phosphorodiamidate oligomers (PMOs) in dystrophin-deficient mdx mice. In the present study, the general
mechanistic significance of the...
Full Text:
Exon-skipping Efficiency
Yin, H., Boisguerin, P., Moulton, H. M., Betts, C., Seow, Y., Boutilier, J
We have recently reported that cell-penetrating peptides (CPPs) and novel chimeric peptides containing CPP (referred as
B peptide) and muscle-targeting peptide (referred as MSP) motifs significantly improve the systemic exon-skipping activity
of morpholino phosphorodiamidate oligomers (PMOs) in dystrophin-deficient mdx mice. In the present study, the general
mechanistic significance of the...
Reproductive tactics and migratory strategies in Pacific and Atlantic salmonines are inextricably linked through the effects of migration (or lack thereof) on age and size at maturity. In this review, we focus on the ecological and evolutionary patterns of freshwater maturation in salmonines, a key process resulting in the diversification...
We have recently reported that cell-penetrating peptides (CPPs) and novel chimeric peptides containing CPP (referred as
B peptide) and muscle-targeting peptide (referred as MSP) motifs significantly improve the systemic exon-skipping activity
of morpholino phosphorodiamidate oligomers (PMOs) in dystrophin-deficient mdx mice. In the present study, the general
mechanistic significance of the...
The Geostationary Coastal and Air Pollution Events (GEO-CAPE) mission was recommended by the National Research Council's (NRC's) Earth Science Decadal Survey to measure tropospheric trace gases and aerosols and coastal ocean phytoplankton, water quality, and biogeochemistry from geostationary orbit, providing continuous observations within the field of view. To fulfill the...