Many Gram-negative bacteria use a type III secretion system (TTSS) to establish a relationship with a host. Pathogens can use the secretion system as a way to deliver proteins known as type III effectors (TTEs) into a host cell and block host defense. The variation and redundancy of the type...
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Characterization of Type Three
Effectors from Pseudomonas syringae
pv. tomato DC3000
CaitlinThireault
Many Gram-negative bacteria use a type III secretion system (TTSS) to establish a relationship with a host. Pathogens can use the secretion system as a way to deliver proteins known as type III effectors (TTEs) into a host cell and block host defense. The variation and redundancy of the type...
Full Text:
Caitlin A. Thireault
Department of Botany and Plant Pathology/BioResource Research
5/20/2010
Many Gram-negative bacteria use a type III secretion system (TTSS) to establish a relationship with a host. Pathogens can use the secretion system as a way to deliver proteins known as type III effectors (TTEs) into a host cell and block host defense. The variation and redundancy of the type...
Many plant-associated Gram-negative bacteria, such a Pseudomonas syringae pv tomato DC3000 (PtoDC3000), use a type III secretion system (T3SS) to establish a host-microbe relationship with compatible plants. The T3SS resembles a molecular injection mechanism that allows the bacteria to deliver type III effectors (T3Es) directly into the cell of the...
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Identification of candidate target proteins of type III effectors
Andres Alvarez, Allison L. Creason, Caitlin A
Many plant-associated Gram-negative bacteria, such a Pseudomonas syringae pv tomato DC3000 (PtoDC3000), use a type III secretion system (T3SS) to establish a host-microbe relationship with compatible plants. The T3SS resembles a molecular injection mechanism that allows the bacteria to deliver type III effectors (T3Es) directly into the cell of the...
Full Text:
type III effectors
Andres Alvarez, Allison L. Creason, Caitlin A. Thireault, Jeff H. Chang
Abstract
Many Gram-negative bacteria use a type III secretion system (T3SS) to establish associations with their hosts. The T3SS is a conduit for direct injection of type-III effector proteins into host cells, where they manipulate the host for the benefit of the infecting bacterium. For plant-associated pathogens, the variations in number...
Many plant-associated Gram-negative bacteria, such a Pseudomonas syringae pv tomato DC3000 (PtoDC3000), use a type III secretion system (T3SS) to establish a host-microbe relationship with compatible plants. The T3SS resembles a molecular injection mechanism that allows the bacteria to deliver type III effectors (T3Es) directly into the cell of the...
Two diametric paradigms have been proposed to model the molecular co-evolution of microbial mutualists and their eukaryotic hosts. In one, mutualist and host exhibit an antagonistic arms race and each partner evolves rapidly to maximize their own fitness from the interaction at potential expense of the other. In the opposing...
Symbioses between microbes and multicellular eukaryotes are found in all biomes, and encompass a spectrum of symbiotic lifestyles that includes parasitism and disease, commensalism, and mutually beneficial interdependent host-microbe relationships. Regardless of outcome, these symbiotic lifestyles are governed by a complex molecular "courtship" between microbe and potential host. This courtship...