The integration of rapid assays, large datasets, informatics, and modeling can overcome current barriers in understanding nanomaterial structure–toxicity relationships by providing a weight-of-the-evidence mechanism to generate hazard rankings for nanomaterials. Here, we present the use of a rapid, low-cost assay to perform screening-level toxicity evaluations of nanomaterials in vivo. Calculated...
The integration of rapid assays, large datasets, informatics, and modeling can overcome current barriers in understanding nanomaterial structure–toxicity relationships by providing a weight-of-the-evidence mechanism to generate hazard rankings for nanomaterials. Here, we present the use of a rapid, low-cost assay to perform screening-level toxicity evaluations of nanomaterials in vivo. Calculated...
The integration of rapid assays, large datasets, informatics, and modeling can overcome current barriers in understanding nanomaterial structure–toxicity relationships by providing a weight-of-the-evidence mechanism to generate hazard rankings for nanomaterials. Here, we present the use of a rapid, low-cost assay to perform screening-level toxicity evaluations of nanomaterials in vivo. Calculated...
There are several issues to be addressed concerning the management and effective use of information (or data), generated from nanotechnology studies in biomedical research and medicine. These data are large in volume, diverse in content, and are beset with gaps and ambiguities in the description and characterization of nanomaterials. In...
Background and motivation: The high-throughput genomics communities have been successfully using standardized spreadsheet-based formats to capture and share data within labs and among public repositories. The nanomedicine community has yet to adopt similar standards to share the diverse and multi-dimensional types of data (including metadata) pertaining to the description and...
In many partially glacierized watersheds glacier recession driven by a warming climate could lead to complex patterns of streamflow response over time, often marked with rapid increases followed by sharp declines, depending on initial glacier ice cover and rate of climate change. Capturing such “phases” of hydrologic response is critical...
In many partially glacierized watersheds glacier recession driven by a warming climate could lead to complex patterns of streamflow response over time, often marked with rapid increases followed by sharp declines, depending on initial glacier ice cover and rate of climate change. Capturing such “phases” of hydrologic response is critical...
In many partially glacierized watersheds glacier recession driven by a warming climate could lead to complex patterns of streamflow response over time, often marked with rapid increases followed by sharp declines, depending on initial glacier ice cover and rate of climate change. Capturing such “phases” of hydrologic response is critical...
The Paisley Caves in Oregon record the oldest directly dated human remains (DNA) in the Western Hemisphere. More than 100 high-precision radiocarbon dates show that deposits containing artifacts and coprolites ranging in age from 12,450 to 2295 ¹⁴C years ago are well stratified. Western Stemmed projectile points were recovered in...