Index Catalog // ScholarsArchive@OSU

Insight into the regulation of quorum sensing antiactivator genes qteE and qslA in Pseudomonas aeruginosa

Creator:: Lawless, Finn
Abstract:: Ubiquitous pathogen Pseudomonas aeruginosa coordinates population-wide activation of virulence genes through quorum sensing (QS), where individuals transition from solo to social behaviors to benefit the population. QS is complex and mechanisms vary from species to species, but the concept is common to the bacterial world and has implications in various...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Janine Trempy, Committee Member, representing Microbiology

Evaluation of peptide phosphorodiamidate morpholino oligomers as a novel antibiotic therapy

Creator:: Kaller, Margo
Abstract:: Peptide-phosphorodiamidate morpholino oligomers (PPMOs) are synthetic DNA mimics that bind and silence gene targets. Through designing PPMOs that silence essential or resistance genes in pathogens, these antisense oligomers could be utilized as novel antimicrobials. Towards this end, my thesis employed minimum inhibitory concentration assays (MICs) to identify PPMOs capable of...
Resource Type:: Masters Thesis
Full Text:: Dr. Bruce Geller for his teaching, advice, and inspiration in this project. Dr. Janine Trempy has

Revealing sequences and modifications of intact proteins using electron fragmentation

Creator:: Franklin, Rachel
Abstract:: People turn to mass spectrometry to answer some of life’s most important questions. From carbon dating of archeological finds to newborn blood screening tests, mass spectrometry allows us to measure molecules which helps advance our knowledge of life and the world we live in. One area of mass spectrometry that...
Resource Type:: Dissertation

Predictors of participation in a prison-based parenting program

Creator:: Schumer, Jean Ellen
Abstract:: The focus of this study was threefold. This research examined the extent to which parenting alliance between incarcerated parents and the caregivers of their children, influences participation of inmate parents in parenting programs. This research explored the extent to which family contact influences participation of inmate parents in parenting programs....
Resource Type:: Dissertation
Full Text:: , Stephanie Bernell, Viktor Bovbjerg, Mark Eddy, Jangho Yoon, Janine Trempy, and Sam Vuchinich, each of whom

Base inclinations for synthetic nucleic acids in solution

Creator:: Jin, Xiaokui
Resource Type:: Dissertation
Full Text:: graduate committee members, Dr. Ken van Holde, Dr. Bob Becker, Dr. Sonia Anderson and Dr. Janine Trempy as

Production and characterization of extracellular polysaccharides produced by Lactobacillus plantarum

Creator:: Youssef-Hakimi, Nilo Fatemeh
Resource Type:: Masters Thesis
Full Text:: , Drs. Mark Daeschel, Janine Trempy, Daniel Selivonchick, and Hillary Carpenter for their advice and

Development of mucosal vaccines for avian influenza A virus composed of recombinant Lactococcus lactis and Streptococcus gordonii

Creator:: Reese, Kaleb A.
Abstract:: Novel mucosal vaccines (LL-M2e, LL-HAe, SG-HAe) were constructed from live, non-pathogenic Lactococcus lactis or Streptococcus gordonii that express conserved regions of HA or M2 antigens from avian influenza virus (AIV) A. All three vaccines evoked antigen-specific serum immunoglobulin G (IgG) responses in vaccinated chickens. The addition of the adjuvant cholera...
Resource Type:: Masters Thesis
Full Text:: Bruslind, Mary Fulton, Theo Dreher, Manoj Pastey, Martin Schuster, Sally Tatala, Janine Trempy, Stephanie

Biophysical analyses of peroxiredoxins and a partner reductase

Creator:: Hall, Andrea Renée
Abstract:: Peroxiredoxins (Prxs) are dominant peroxide-reducing enzymes with two important roles: they protect all organisms from oxidative damage induced by peroxides, and in eukaryotes, they participate in hydrogen peroxide signaling pathways. This dissertation presents studies aimed at the biophysical characterization of select Prxs and a Prx reductase to elucidate their structure-function...
Resource Type:: Dissertation
Full Text:: personally and scientifically, thank you. I thank my graduate committee members, Elisar Barbar, Janine

Factors contributing to the formation of CC-->TT tandem mutations

Creator:: Skinner, Amy M.
Abstract:: The multistage model of carcinogenesis states that an accumulation of mutations in genes that are important for maintaining cellular homeostasis may lead to cancer. A specific type of mutation observed in particular types of cancer is the CC-->TT mutation found in the TP53 gene of patients with basal or squamous...
Resource Type:: Dissertation
Full Text:: offered by Dr. Janine Trempy following my qualifying examination. The author wishes to thank her

ScholarsArchive@OSU

Insight into the regulation of quorum sensing antiactivator genes qteE and qslA in Pseudomonas aeruginosa

Evaluation of peptide phosphorodiamidate morpholino oligomers as a novel antibiotic therapy

Revealing sequences and modifications of intact proteins using electron fragmentation

Predictors of participation in a prison-based parenting program

Base inclinations for synthetic nucleic acids in solution

Production and characterization of extracellular polysaccharides produced by Lactobacillus plantarum

Development of mucosal vaccines for avian influenza A virus composed of recombinant Lactococcus lactis and Streptococcus gordonii

Biophysical analyses of peroxiredoxins and a partner reductase

Factors contributing to the formation of CC-->TT tandem mutations

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