While the experimental Alzheimer's drugs recently developed by pharmaceutical companies failed to stop the progression of Alzheimer's disease, clinicians strive to seek clues on how the patients would be when they visit back next year, based upon the patients' current clinical and neuropathologic diagnosis results. This is related to how...
An enantioselective 1,3-dipolar cycloaddition of 2-cyclo-hexene-1-one and azomethine ylide generated in situ from isatin and amino ester was developed by employing proline sulfonamide as the catalyst. Consequently, novel polycyclic spirooxindole scaffolds with three contiguous stereocenters were prepared in high yield (up to 95%) with excellent diastereo- (> 20:1 dr) and...
Nanotechnology products have long since made their way to markets around the world increasing the concerns about whether nanomaterials pose a risk to our environment or health. It has been suggested that engineered nanomaterial (ENM) with broad applications and rapid commercialization need better risk assessment and regulation. However, the refinement...
Interest in personal computer networks has grown
rapidly in recent years. As the personal computer
becomes more and more popular, implementing computer
networks on those small computers has become an
interesting topic. Such networks are usually inexpensive
and can be easily installed and maintained.
In this thesis work, CLASSLAN, such...
Traditionally linear actuator applications are addressed by the use of hydraulic systems. The high maintenance cost and poor reliability will always be the most critical problem in the real applications. Benefited from both the high mechanical advantage of the roll screw and the simple structure of the switched reluctance motor,...
Seaweeds have gained tremendous recognition as a highly nutritious and sustainable crop. The diverse components of seaweeds are known to exhibit a wide range of bioactivities, including anti-inflammatory, anti-diabetic, and cardiovascular health benefits. One such promising seaweed is Pacific dulse (Devaleraea mollis). While it holds great cultivating potential on the...
Three analytical methods for determination of aroma compounds in alcoholic beverages were developed and validated. These methods are sensitive and reliable that can be applied to analyze volatile phenols, stale aldehydes as well as some highly volatile aromas in alcoholic beverages. In the first study, an ethylene glycol (EG) polydimethylsiloxane...
Full integration of CMOS low noise amplifiers (LNA) presents a challenge for low
cost CMOS receiver systems. A critical problem faced in the design of an RF CMOS LNA
is the inaccurate high-frequency noise model of the MOSFET implemented in circuit
simulators such as SPICE. Silicon-based monolithic inductors are another...
Transmit beamforming is an important technique employed to improve efficiency and signal quality in wireless communication systems by steering signals towards their in- tended users. It often arises jointly with the antenna selection problem due to various reasons, such as limited number of radio frequency (RF) chains and energy/resource effi-...
Crowdsourcing is a popular paradigm to address the high demands for labeled data in big data deluge. It aims to produce accurate labels by effectively integrating noisy, non-expert labeling from crowdsourced workers (annotators). The machine learning community has been studying effective crowdsourcing methods for many years, and many models and...