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Vacuum ultraviolet absorption studies of model sugar compounds

Creator:: Dickinson, Helen Rose
Abstract:: Vacuum ultraviolet absorption spectra of 13 model sugar compounds were measured in the energy range of 50 to 80 kK. The model sugars included three simple alcohols, four simple ethers, four cyclic alcohol-ether compounds, and two dioxanes. All spectra show transition bands in the energy region 50 to 65 kK....
Resource Type:: Dissertation

Monophoton decay time fluorometry : theory, design, and application to biochemical systems

Creator:: Schuyler, Robert John
Abstract:: In the determination of binding heterogeneity and rotational diffusion relaxation times, fluorescence decay curves often take the form of sums of exponential decay times. An instrument is described which includes features permitting the collection of high precision time decay data, which may successfully be resolved into component decays. The instrument...
Resource Type:: Dissertation

Hexachlorophene : its absorption, distribution, excretion, and biotransformation in the rat and rabbit and in vitro interaction with rat liver microsomes

Creator:: Gandolfi, Allen Jay
Abstract:: The fate of hexachlorophene, a widely used bactericide, was investigated using both intact male rats and rabbits and liver microsomes from male rats. Hexachlorophene administered intraperitoneally was found to be rapidly absorbed and distributed to all the tissues of the animals. Excretion of the chemical in both species occurred slowly,...
Resource Type:: Dissertation
Full Text:: . Microsomes were shown to strongly bind large amounts of hexachlorophene. Fur- thermore, at low

The effect of hexachlorophene and related compounds on torula yeast glucose-6-phosphate dehydrogenase and some other dehydrogenase enzymes

Creator:: Wang, Jun-Lan
Abstract:: Low concentrations of hexachlorophene (HCP) inhibit a number of pyridine nucleotide-linked dehydrogenase enzymes. The I₅₀ HCP concentrations were 105 μM for pig heart isocitrate dehydrogenase (ICD), 65 μM for horse liver alcohol dehydrogenase, 39 μM for torula yeast glucose-6-phosphate dehydrogenase (G6PD), 6.0 μM for beef heart malate dehydrogenase, and 1.6...
Resource Type:: Dissertation

The β-glucosidase system of the thermophilic fungus Chaetomium thermophile

Creator:: Lusis, Aldons Jekabs
Abstract:: The thermophilic fungus Chaetomium thermophile was shown to contain three major β-glucosidases, a cell-bound cellobiase, a cellbound aryl-β-glucosidase and an extracellular aryl-β-glucosidase. The enzymes were partially purified and studied with respect to thermal stability and certain kinetic parameters. Two of the β-glucosidases are fairly stable at the maximum growth temperature...
Resource Type:: Dissertation

Kinetic studies of the oxygen requirement of some amine oxidases

Creator:: Swindell, Robert Malcolm
Abstract:: Some kinetics of the oxygen requirement of amine oxidases have been investigated using bovine plasma monoamine oxidase (PAO) and pea seedling diamine oxidase (DAO). A system is described for studying enzyme reactions under controlled oxygen tension and in an O₂-free N₂ atmosphere. O₂ Km values were determined at two different...
Resource Type:: Masters Thesis

Oligoribonucleotides directed at ribosomal protein binding sites as inhibitors of ribosomal small subunit assembly and as possible antibiotics

Creator:: Thompson, Cynthia Sue
Abstract:: The effects of oligoribonucleotides of identical or similar sequences to a ribosomal protein binding site, specifically S8, on prokaryotic 30S ribosomal assembly were investigated in Escherichia coli. The oligoribonucleotides were expected to bind to the target protein S8 and block its incorporation into the 30S subunit, resulting in a nonfunctional...
Resource Type:: Dissertation

The effect of selenium deficiency on the fatty acid metabolism of rats and lambs

Creator:: Fischer, William Carl
Abstract:: Selenium deficiency in rats results in increased carbon metabolism, approaching twice the rate of selenium supplemented animals (normal). This is also reflected in a 50 percent increase in lysosomal enzyme activity in tissues of selenium deficient animals. Isolation of rat liver lysosomes shows a 17 percent increase in membrane thickness...
Resource Type:: Dissertation

Prothoracicotropic hormone, cyclic nucleotides, and proctolin in insect central nervous system

Creator:: Kingan, Timothy Gilmore
Abstract:: Prothoracicotropic hormone has been partially purified from whole heads of tobacco hornworm larvae, Manduca sexta. Activity was followed with a larval bioassay. Activity was purified 4400 fold from crude extracts. The hormone was found to be a heat-stable polypeptide with an approximate molecular weight of 25,000 Daltons. The hormone has...
Resource Type:: Dissertation

Isoprenoids of bovine aorta : isolation, purification, and biosynthesis

Creator:: Adams, Gerald Springer
Resource Type:: Dissertation
Full Text:: tissue, acetate-C14 was shown to be incorporated into sterols. Fur- thermore, a number of investigators

ScholarsArchive@OSU

Vacuum ultraviolet absorption studies of model sugar compounds

Monophoton decay time fluorometry : theory, design, and application to biochemical systems

Hexachlorophene : its absorption, distribution, excretion, and biotransformation in the rat and rabbit and in vitro interaction with rat liver microsomes

The effect of hexachlorophene and related compounds on torula yeast glucose-6-phosphate dehydrogenase and some other dehydrogenase enzymes

The β-glucosidase system of the thermophilic fungus Chaetomium thermophile

Kinetic studies of the oxygen requirement of some amine oxidases

Oligoribonucleotides directed at ribosomal protein binding sites as inhibitors of ribosomal small subunit assembly and as possible antibiotics

The effect of selenium deficiency on the fatty acid metabolism of rats and lambs

Prothoracicotropic hormone, cyclic nucleotides, and proctolin in insect central nervous system

Isoprenoids of bovine aorta : isolation, purification, and biosynthesis

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