Index Catalog // ScholarsArchive@OSU

Creator:: Amari, Khalid, Di Donato, Martin, Dolja, Valerian V., and Heinlein, Manfred
Abstract:: Viruses are obligatory parasites that depend on host cellular factors for their replication as well as for their local and systemic movement to establish infection. Although myosin motors are thought to contribute to plant virus infection, their exact roles in the specific infection steps have not been addressed. Here we...
Resource Type:: Article

Creator:: Koonin, Eugene V. and Dolja, Valerian V.
Abstract:: Viruses and/or virus-like selfish elements are associated with all cellular life forms and are the most abundant biological entities on Earth, with the number of virus particles in many environments exceeding the number of cells by one to two orders of magnitude. The genetic diversity of viruses is commensurately enormous...
Resource Type:: Article

Creator:: Peremyslov, Valera V., Morgun, Eva A., Kurth, Elizabeth G., Makarova, Kira S., Koonin, Eugene V., and Dolja, Valerian V.
Abstract:: To characterize the mechanism through which myosin XI-K attaches to its principal endomembrane cargo, a yeast two-hybrid library of Arabidopsis thaliana cDNAs was screened using the myosin cargo binding domain as bait. This screen identified two previously uncharacterized transmembrane proteins (hereinafter myosin binding proteins or MyoB1/2) that share a myosin...
Resource Type:: Article

Creator:: Maree, Hans J., Almeida, Rodrigo P. P., Bester, Rachelle, Chooi, Kar Mun, Cohen, Daniel, Dolja, Valerian V., Fuchs, Marc F., Golino, Deborah A., Jooste, Anna E. C., Martelli, Giovanni P., Naidu, Rayapati A., Rowhani, Adib, Saldarelli, Pasquale, and Burger, Johan T.
Abstract:: Grapevine leafroll disease (GLD) is one of the most important grapevine viral diseases affecting grapevines worldwide. The impact on vine health, crop yield, and quality is difficult to assess due to a high number of variables, but significant economic losses are consistently reported over the lifespan of a vineyard if...
Resource Type:: Article

Creator:: Dolja, Valerian V. and Koonin, Eugene V.
Abstract:: Important progress in understanding replication, interactions with host plants, and evolution of closteroviruses enabled engineering of several vectors for gene expression and virus-induced gene silencing. Due to the broad host range of closteroviruses, these vectors expanded vector applicability to include important woody plants such as citrus and grapevine. Furthermore, large...
Resource Type:: Article

Creator:: Kurth, Elizabeth G., Peremyslov, Valera V., Prokhnevsky, Alexey I., Kasschau, Kristin D., Miller, Marilyn, Carrington, James C., and Dolja, Valerian V.
Abstract:: The improvement of the agricultural and wine-making qualities of the grapevine (Vitis vinifera) is hampered by adherence to traditional varieties, the recalcitrance of this plant to genetic modifications, and public resistance to genetically modified organism (GMO) technologies. To address these challenges, we developed an RNA virus-based vector for the introduction...
Resource Type:: Article

Creator:: Peremyslov, Valera V., Mockler, Todd C., Filichkin, Sergei A., Fox, Samuel E., Jaiswal, Pankaj, Makarova, Kira S., Koonin, Eugene V., and Dolja, Valerian V.
Abstract:: Plants possess two myosin classes, VIII and XI. The myosins XI are implicated in organelle transport, filamentous actin organization, and cell and plant growth. Due to the large size of myosin gene families, knowledge of these molecular motors remains patchy. Using deep transcriptome sequencing and bioinformatics, we systematically investigated myosin...
Resource Type:: Article

Creator:: Lakatos, Lóránt, Csorba, Tibor, Pantaleo, Vitantonio, Chapman, Elisabeth J., Carrington, James C., Liu, Yu-Ping, Dolja, Valerian V., Calvino, Lourdes Fernández, López-Moya, Juan José, and Burgyán, József
Abstract:: RNA silencing is an evolutionarily conserved system that functions as an antiviral mechanism in higher plants and insects. To counteract RNA silencing, viruses express silencing suppressors that interfere with both siRNA- and microRNA-guided silencing pathways. We used comparative in vitro and in vivo approaches to analyse the molecular mechanism of...
Resource Type:: Article

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