Index Catalog // ScholarsArchive@OSU

Analytical chemistry of pentazocine metabolites produced by the greyhound

Creator:: Xiao, Guang
Abstract:: This thesis concerns itself mainly with analytical methods development and analytical applications in the field of drug metabolism studies. The determination of the analgesic pentazocine and its metabolites in the greyhound are studied. Pentazocine and all of its possible metabolites are isolated from the greyhound urine by a the multi-solvent...
Resource Type:: Dissertation
Full Text:: by the greyhound AN ABSTRACT OF THE THESIS OF Guanq Xiao for the degree of Doctor of Philosophy

Coulomb Explosion in Moderately Intense Nanosecond Laser Fields

Creator:: Yao, Yuzhong
Abstract:: In this dissertation, I present experimental observations of multiply charged atomic ions (MCAI) generated from interactions of atomic/molecular clusters with moderately intense nanosecond laser pulses. This process is also known as Coulomb explosion (CE) and it has been extensively studied in intense laser fields using ultrashort pulses. Several prevailing theories...
Resource Type:: Dissertation
Full Text:: . Lan Xue, Dr. Chong Fang, Dr. David McIntyre, and Dr. Weihong Qiu for their insightful comments and

Transition Metal Oxides for Aqueous Electrochemical Energy Storage

Creator:: Jiang, Heng
Abstract:: In the 21st century, environmental deterioration is now an indisputable fact. Reliable and economically viable electricity systems based on renewable sources are urgently needed to replace the environmentally detrimental fossil fuels. The feasibility of incorporating renewable-but-intermittent solar and wind energy heavily depends on the development of cost-effective and safe technologies,...
Resource Type:: Dissertation
Full Text:: throughout my Ph.D. studies. I am also grateful to Dr. Chih-hung Chang for being my GCR member to help me

Preparation and Properties of Porous Carbon Materials

Creator:: Xing, Zhenyu
Abstract:: Porous carbon is indispensable in modern technology applications. It is used for energy storage, gas separation, water purification, catalyst support, and chromatography. The diversity of its applications stems from its unique properties, including high specific surface area, tunable pore volume, and chemical stability. Specifically, the large surface area provides high...
Resource Type:: Dissertation
Full Text:: Michael Lerner, Professor May Nyman, and Professor Chih-Hung Chang. I would also thank Professor

Formation of hybrid supramolecular assemblies using biological molecules and transition metals

Creator:: Smith, Rachelle M. S.
Abstract:: Naturally occurring assemblies, such as DNA and proteins, utilize intermolecular forces (i.e H-bonding and van der Waals) to assemble. Utilizing these electrostatic interactions has only just started in the past five decades to be a tool used in synthetic chemistry in what is known as supramolecular chemistry. Supramolecular chemistry has...
Resource Type:: Dissertation

Fabrication and application of polymer based microfluidic devices

Creator:: Koesdjojo, Myra T.
Abstract:: The concept of reducing laboratory operations in scale such that they fit on a microfluidic chip has been met with great enthusiasm. Lab-on-a-chip devices promise to be cost effective to operate due to reduced reagent consumption, have the potential to offer shorter analysis times due to their short path lengths,...
Resource Type:: Dissertation
Full Text:: to Dr. Chih-hung Chang, Dr. Claudia Maier, Dr. David Hackleman, and Dr. Michael Penner, for their

Detection techniques for biomolecules using semi-conductor nanocrystals and magnetic beads as labels

Creator:: Chatterjee, Esha
Abstract:: Continued interest in the development of miniaturized and portable analytical platforms necessitates the exploration of sensitive methods for the detection of trace analytes. Nanomaterials, on account of their unique physical and chemical properties, are not only able to overcome many limitations of traditional detection reagents but also enable the exploration...
Resource Type:: Dissertation
Full Text:: . Michael Lerner, Dr. Chih-hung (Alex) Chang, Dr. Neal Sleszynski and Dr. Michael Qian, members of my

Magnetic particles for selective extraction of trace analytes in microfluidic devices

Creator:: Tennico, Yolanda H.
Abstract:: The development of micro total analysis systems (µTAS), also called “lab-on-a-chip”, or microfluidic analysis systems, is presented in this dissertation. Various research areas, covering subjects from magnetic particles synthesis to novel microchip fabrication techniques, are explored to develop a lab-on-a-chip system capable of performing magnetic bead-based bioassays. These devices are...
Resource Type:: Dissertation
Full Text:: -hung (Alex) Chang, Dr. Michael Lerner, Dr. Alexey Shvarev, and Dr. Alena Paulenova, for their

Femtosecond Stimulated Raman Studies of Excited State Structural Events

Creator:: Tang, Longteng
Abstract:: Femtosecond stimulated Raman spectroscopy (FSRS) is an ultrafast vibrational technique which allows rapid collection of Raman spectra with simultaneously high temporal and spectral resolution. With the recent development of FSRS methodology, three FSRS techniques (conventional, tunable, and anti-Stokes) have been implemented in our laboratory to dissect the excited state structural...
Resource Type:: Dissertation
Full Text:: thank Professor Michael Lerner, Professor Yun-Shik Lee and Professor Chih-hung Chang for severing on

Synthesis of Intercalation Compounds and Nanocomposites of Inorganic Layered Hosts

Creator:: Liyanage, Medagama Liyanage Amila Udayanga
Abstract:: Novel synthetic strategies are developed to prepare new intercalation compounds and nanocomposites with several layered hosts (NiPS₃, Na-montmorillonite, MoS₂ and MoO₃). In these products, alkali metals are ionic intercalates and linear polymers, dendrimers or amines act as co-intercalates. In addition to new synthetic approaches, new structures are identified and characterized....
Resource Type:: Dissertation
Full Text:: . Keszler, MAS Subramanian, Vincent T. Remcho, and Chih-hung (Alex) Chang for serving on my graduate

New Approaches for Quantifying Target and Estimating Suspect PFAS in Complex Media

Creator:: Cao, Dunping
Abstract:: Per- and polyfluoroalkyl substances (PFAS) are a group of anthropogenic compounds that are used ubiquitously in different industrial fields. However, concerns regarding the potential health impacts of PFAS, including perfluoroalkyl carboxylic acids (PFCAs) and perfluoroalkyl sulfonates (PFSAs), has raised stakeholder interest regarding continued use of PFAS. Analytical methods for PFAS...
Resource Type:: Dissertation
Full Text:: Schwichtenberg proposed the concept, Dr. Lan Xue and Chenyang Duan helped with the statistics and coding. Derek

Storage Battery Chemistries with Earth Abundant Charge Carriers

Creator:: Hong, Jessica Junghwa
Abstract:: The demand for the development of sustainable energy is an all time high as we burn through limited fossil fuel reserves and as environmental concerns rise every year. Renewable energy sources such as wind and solar power have limitations due to inconsistent power supply that cannot meet the regular needs...
Resource Type:: Dissertation

Cost Efficient Fabrication Techniques for Microchips and Interconnects Enabled by Polycaprolactone

Creator:: Koesdjojo, Myra T., Nammoonnoy, Jintana, Wu, Yuanyuan, Frederick, Ryan T., and Remcho, Vincent T.
Abstract:: In this paper we present a novel fabrication technique that utilizes polycaprolactone (PCL) as bonding media due to its low melting temperature property. PCL is biodegradable polyester with a melting point of 60°C, and a glass transition temperature of -60°C [1-10]. It is employed as a rapid bonding technique in...
Resource Type:: Article
Full Text:: . Anal. Chem. 2009, 81, 1652-1659. (22) Lin, C.H., Chao, C.H., Lan, C.W. Sens. Actuators B. 2007, 121

Fundamental Studies of the Structure-Property Correlations of Na-ion and K-ion Storage in Non-Graphitic Carbon

Creator:: Li, Zhifei
Abstract:: Grid-scale energy storage systems are urgently needed to increase the flexibility and rigidity of the grid for modern society and take full advantage of the renewable green energy resources such as solar energy and wind energy. Na-ion batteries (NIBs) and K-ion batteries (KIBs) have been emerged as one of the...
Resource Type:: Dissertation
Full Text:: Laboratory. I am grateful to Dr. Chih-Hung Chang and Dr. Changqing Pan for their help on the Raman tests. I

Innovative Bioanalytical Tools & Methods for Combinatorial Non-Coding RNA Analysis

Creator:: Zhang, Lulu
Abstract:: Recently researchers have discovered that groups of small non-coding RNAs (ncRNAs) play regulatory roles in gene expression and participate in various biological processes. For example, pathogenesis of many diseases, cell cycle regulation, and signaling pathways. Intracellular and live cell imaging of small ncRNA groups will reveal their relative expression levels...
Resource Type:: Dissertation

Hydrophobicity, Anion Exchange, and Phytoaccumulation of Per- and Polyfluoroalkyl Substances (PFAS): Retention and Remediation

Creator:: Parker, Bethany A.
Abstract:: Per- and polyfluoroalkyl substances (PFAS) are a group of contaminants of great concern due to their toxicity and ubiquity in the environment. Remediation efforts historically have focused on granular activated carbon (GAC) because of its low maintenance and relatively low cost. However, GAC is not PFAS selective and is especially...
Resource Type:: Dissertation
Full Text:: . 14. Li, P.; Oyang, X.; Zhao, Y.; Tu, T.; Tian, X.; Li, L.; Zhao, Y.; Li, J.; Xiao, Z

Low-Dose X-Ray Radiation Effects On the Proteomic Profiles of Hippocampus, Cortex, and Cerebellum of Contextual Fear Conditioning and Novel Object Recognition Trained Mice

Creator:: Koluda, Rony
Abstract:: Radiation exposure to the brain can occur from a variety of events, including space missions, nuclear accidents, and clinical treatments. The effects of high dose radiation are well studied, but those of lower dosage are more elusive. Decline of memory and cognition is observed in patients exposed to low dose...
Resource Type:: Masters Thesis
Full Text:: . Tseng, E. Giedzinski, A. Izadi, T. Suarez, M. L. Lan, K. K. Tran, M. M. Acharya, G. A. Nelson, J

Nonmuscle myosins II-B and Va are components of detergentresistant membrane skeletons derived from mouse forebrain

Creator:: Ishmael, Jane E., Safic, Masa, Amparan, David, Vogel, Walter K., Pham, Tuyen, Marley, Kevin, Filtz, Theresa M., and Maier, Claudia S.
Abstract:: Myosins are actin-based molecular motors that may have specialized trafficking and contractile functions in cytoskeletal compartments that lack microtubules. The postsynaptic excitatory synapse is one such specialization, yet little is known about the spatial organization of myosin motor proteins in the mature brain. We used a proteomics approach to determine...
Resource Type:: Preprint and Article
Full Text:: metabotropic glutamate receptor- interacting protein that is enriched at excitatory synapses (Xiao et al. 1998

Synthesis and Characterization of Novel Metal-Oxo Clusters as the Building Blocks in Nature and Synthesis

Creator:: Amiri, Mehran
Abstract:: Metal-oxo clusters can be described as soluble pieces of metal-oxide frameworks. Metal-oxo clusters are also the building blocks for the Metal-Organic Frameworks (MOFs) and coordination polymers. A better knowledge of metal-oxo clusters helps fundamentally understand geosciences, molecular engineering, catalysis, single-molecule magnetism, and MOFs for synthesis, design, and modification of these...
Resource Type:: Dissertation

Synthesis, characterization, and structural modeling of graphite intercalation compounds with fluoroanions

Creator:: Yan, Wei
Abstract:: New synthetic strategies have been investigated for nano-dimensioned graphite particles or even isolated graphene sheets. One approach is to prepare graphite intercalation compounds (GICs) with low layer charge density and appropriate gallery height, followed by the colloidal dispersion or exfoliation of the resulting GICs. A series of anions has been...
Resource Type:: Dissertation

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