Index Catalog // ScholarsArchive@OSU

H. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish model

Creator:: Neal, James T., Peterson, Tracy S., Kent, Michael L., and Guillemin, Karen
Abstract:: Infection with Helicobacter pylori is a major risk factor for the development of gastric cancer, and infection with strains carrying the virulence factor CagA significantly increases this risk. To investigate the mechanisms by which CagA promotes carcinogenesis, we generated transgenic zebrafish expressing CagA ubiquitously or in the anterior intestine. Transgenic...
Resource Type:: Article
Full Text:: Guillemin1,§ RESEARCH ARTICLE D ise as e M od el s & M ec ha ni sm s D M M Disease

Analysis of the genome of leporid herpesvirus 4

Creator:: Babra, Bobby, Watson, Gregory, Xu, Wayne, Jeffrey, Brendan, Xu, Jia-Rong, Rockey, Dan, Rohrmann, George, and Jin, Ling
Abstract:: The genome of a herpesvirus highly pathogenic to rabbits, leporid herpesvirus 4 (LHV-4), was analyzed using high-throughput DNA sequencing technology and primer walking. The assembled DNA sequences were further verified by restriction endonuclease digestion and Southern blot analyses. The total length of the LHV-4 genome was determined to be about...
Resource Type:: Article
Full Text:: (version 2.5). 65597 sequence reads 333 were assembled with Newbler software (454 Life Technology) into

An investigation of carbon and nitrogen metabolism through a genomic analysis of the genus Nitrobacter

Creator:: Starkenburg, Shawn R.
Abstract:: The chemolithoautotrophic nitrite oxidizing bacteria (NOB) participate in the biogeochemical cycling of nitrogen by catalyzing and conserving energy from the oxidation of nitrite (NO₂-) to nitrate (NO₃-) via a nitrite oxidoreductase (NXR). The main objective of this work was to comparatively annotate and analyze the genome sequences of Nitrobacter winogradskyi...
Resource Type:: Dissertation

Symbiotic and saprophytic characteristics of a soil population of Rhizobium leguminosarum bv. trifolii

Creator:: Yap, Kathryn H. M.
Abstract:: Although much has been learned about the comparative nodulating behavior of simple mixtures of rhizobial strains under non-soil situations, it is unclear how these findings relate to the factors influencing nodulation success by the complex mixtures of strains found within soil-borne rhizobial populations. Information on the structure and physiological behavior...
Resource Type:: Masters Thesis
Full Text:: the enzymes. Enzyme EC no. Substrate and coupling enzymes (amt) Assay buffer and salt supplements(amt

Development of mucosal vaccines for avian influenza A virus composed of recombinant Lactococcus lactis and Streptococcus gordonii

Creator:: Reese, Kaleb A.
Abstract:: Novel mucosal vaccines (LL-M2e, LL-HAe, SG-HAe) were constructed from live, non-pathogenic Lactococcus lactis or Streptococcus gordonii that express conserved regions of HA or M2 antigens from avian influenza virus (AIV) A. All three vaccines evoked antigen-specific serum immunoglobulin G (IgG) responses in vaccinated chickens. The addition of the adjuvant cholera...
Resource Type:: Masters Thesis

Single-Cell Genomics of Uncultivated Marine Bacteria

Creator:: Landry, Zachary
Abstract:: Historically, the difficulty of obtaining pure cultures of abundant marine microbial plankton has an obstacle to reconstructing the underlying mechanisms of biogeochemistry in the ocean. While a number of dominant marine species from the ocean surface have been cultured, the dominant microbial plankton of the dark ocean proved far more...
Resource Type:: Dissertation

Analysis of Mutations Affecting Cooperation in Pseudomonas aeruginosa Populations

Creator:: Robinson, Tanner M.
Abstract:: In a process called quorum sensing (QS), the bacterial pathogen Pseudomonas aeruginosa uses small diffusible signals to coordinate cooperative behaviors via secreted “public goods”. Under QS-dependent growth conditions, social cheaters arise with mutations in lasR, the gene for the primary QS signal receptor. These cheaters do not produce public goods....
Resource Type:: Masters Thesis
Full Text:: . 8. Pesci EC, Iglewski BH. 1997. The chain of command in Pseudomonas quorum sensing. Trends

Metagenomics: Microbial diversity through a scratched lens

Creator:: Temperton, Ben and Giovannoni, Stephen J.
Abstract:: Since nucleic acids were first extracted directly from the environment and sequenced, metagenomics has grown to one of the most data-rich and pervasive techniques for understanding the taxonomic and functional diversity of microbial communities. In the last decade, cheaper sequencing has democratized the application of metagenomics and generated billions of...
Resource Type:: Article
Full Text:: 332 analysis of gene function and kinetics via heterologous gene expression 333 in E. coli, made

Soil and rumen microbial responses to photooxidized grass straw

Creator:: Park, Jerry Eugene
Abstract:: Straw has many uses, as feed, roughage, animal bedding, but these requirements are not sufficient to utilize the available production. In areas where grasskseed is produced, post-harvest straw is burned in the field to help prevent crop disease the following year. This treatment is very wasteful in terms of straw...
Resource Type:: Masters Thesis
Full Text:: , Grant EC-00266-01, coordinated through the Oregon State University Air Resources Center, R. M

Pathways and enzymes involved in glucose catabolism by lactic streptococci

Creator:: Nandan, Rajiva
Abstract:: The enzymes and pathways involved in the catabolism of glucose by several strains of Streptococcus diacetilactis, Streptococcus cremoris, and Streptococcus lactis, commonly called the lactic streptococci, were studied. The presence of aldolase, triosephosphate isomerase and alcohol dehydrogenase in these organisms provided evidence for the operation of the Embden-Meyerhof-Parnas (EMP) pathway...
Resource Type:: Dissertation
Full Text:: SH + EbNH-CO(CH2)5 + Ec. FADH2 Ec. FADH2 + NAD+ Ec. FAD + NADH + H+ 27 Net. CH3COCOOH

ScholarsArchive@OSU

H. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish model

Analysis of the genome of leporid herpesvirus 4

An investigation of carbon and nitrogen metabolism through a genomic analysis of the genus Nitrobacter

Symbiotic and saprophytic characteristics of a soil population of Rhizobium leguminosarum bv. trifolii

Development of mucosal vaccines for avian influenza A virus composed of recombinant Lactococcus lactis and Streptococcus gordonii

Single-Cell Genomics of Uncultivated Marine Bacteria

Analysis of Mutations Affecting Cooperation in Pseudomonas aeruginosa Populations

Metagenomics: Microbial diversity through a scratched lens

Soil and rumen microbial responses to photooxidized grass straw

Pathways and enzymes involved in glucose catabolism by lactic streptococci

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