In supervised learning, label information can be provided at different levels of granularity. For small datasets, it is possible to acquire a label for each data instance. However, in the big-data regime, this fine granularity approach is prohibitively costly. For example, in semi-supervised learning, only a limited number of samples...
Analysis of substrate noise coupling has been performed for a 0.18¹m lightly doped silicon germanium BiCMOS process. Techniques to minimize noise coupling in the chip and board design are presented, as well as methods for accurate modeling for substrate noise coupling simulations. Measurements from a test chip were taken to...
Topology optimization (TO) is a mathematical method to find the optimal size, shape and connectivity of a domain under specified conditions, and has had many applications in engineering design. However, challenges remain in realizing TO as an effective design tool for many design situations. Uncertainty is ubiquitous in nature and...
The thrust of this thesis is to study oral solid dosage formulation using hot melt coating method and to use pharmacokinetic modeling and simulation (PK M&S) as a tool that can help to predict pharmacokinetics of a drug in human and the probability of passing various bioequivalence criteria of the...
The study of the diversity of multivariate objects shares common characteristics across disciplines, including ecology and organizational management. Nevertheless, experts in these two disciplines have adopted somewhat separate diversity concepts and analysis techniques, limiting the ability of potentially sharing and cross comparing these concerns. Moreover, while complex diversity data may...
M. avium is an opportunistic pathogen that primarily infects macrophages. In order to survive within the macrophage, M. avium secretes proteins into the host cell cytoplasm to inhibit specific functions such as phagosome acidification, altering pathways as well as initiating apoptosis. However, little is known about how those secreted proteins...
For my CSSA portfolio, I developed a graduate-level education course about disability in the United States and in higher education. In this paper, I will provide an introduction to my life and work in disability support services, and how my experience as a disability support services professional and graduate student...
Communication is an aspect of healthcare that affects healthcare providers and patients at each step of their medical journey. The purpose of this research is to identify the effects that language barriers cause between healthcare workers and patients and the patients’ families and how those effects are perceived by and...
The phenomenon of phantom limb pain has been well documented for centuries, but little clinical work has been done to alleviate it. Physician and neuroscientist Vilayanur S. Ramachandran began researching this condition nearly two decades ago, and has discovered a promising alternative treatment: mirror-box therapy. This therapy is not yet...
Microbial communities in Arctic coastal lagoons drive biogeochemical cycles at the terrestrial-marine interface and help to determine the fate and form of resources like nitrogen (N) and carbon (C) as they are delivered to the Arctic Ocean. Though rising rates of primary production in the Arctic Ocean are well-characterized, the...