Index Catalog // ScholarsArchive@OSU

Functional consequences of microRNA regulation by polycyclic aromatic hydrocarbons in 3D human bronchial epithelial cells

Creator:: Mans, Michael-Andres D.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are a class of contaminants ubiquitous in the environment and result from the incomplete combustion of fossil fuels. Many PAHs have been identified as procarcinogenic, and are metabolized to form DNA adducts; however, other mechanisms also may contribute to toxicity and help explain differences in toxicity...
Resource Type:: Undergraduate Thesis
Full Text:: /articles/PMC5759260/. Chen S, Li P, Yang R, Cheng R, Zhang F, Wang Y, Chen X, Sun Q, Zang W, Du Y, et al

Impact of Polycyclic Aromatic Hydrocarbons on Barrier Function Toxicity in 3D Lung Model from Normal and Asthmatic Donor Cells

Creator:: Huynh, Celine T.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are known to cause adverse health effects in the human lung. Here, we evaluated biomarkers relevant for PAH toxicity in a 3D human primary bronchial epithelial cell (HBEC) model collected from normal and asthmatic donors. We previously found that PAHs decrease cellular barrier function integrity, which...
Resource Type:: Honors College Thesis
Full Text:: interface. Toxicol Appl Pharmacol. 379:114644. doi:10.1016/j.taap.2019.114644. Chen M, Yang T, Meng X, Sun

Understanding polycyclic aromatic hydrocarbon (PAH) toxicity and inflammation in human bronchial epithelial cells

Creator:: Valdez, Teresa
Abstract:: There is increased emphasis on understanding cumulative risk from the combined effects of chemical and non-chemical stressors as it relates to public health. Recent animal studies have identified pulmonary inflammation as a possible modifier and risk factor for chemical toxicity in the lung after exposure to inhaled pollutants; however, little...
Resource Type:: Honors College Thesis
Full Text:: associated with increased barrier dysfunction (Chang et al.,2019; Yang et al., 2017). Barrier integrity is

Enhancing Protocols to Improve Consistency Across Nanotoxicology Studies

Creator:: Luker, Sabrina R.
Abstract:: In current nanotoxicology research, there is a lack of standardization in reporting of zebrafish exposure media and sonication practices. This lack of standardization in use and reporting methods has made reproducing nanoparticle (NP) toxicity results between labs a common issue. It is important to have a standardized way of reporting...
Resource Type:: Undergraduate Thesis
Full Text:: ., Ltd., China) Bath 30 min. 100 W, 40 kHz 180000 3000 TEM MQ (Yang, Pan, Wang, & Zhao, 2017

Bacterial seed endophytes of Douglas-fir (Pseudotsuga menziesii) and their potential to confer drought tolerance

Creator:: Hatwal, Shikhar
Abstract:: Bacterial endophytes have the potential to confer benefits to Douglas-fir ( Pseudotsuga menziesii ), for instance drought tolerance. Bacterial endophytes originating from seeds are especially important. This is because seed endophytes are more likely to be the first endophytes to get established within the young host plant. The goals of...
Resource Type:: Undergraduate Thesis
Full Text:: soaking them in 10% bleach for 24 hours. Potting soil (Sun Gro Horticulture, Agawam, Massachusetts) was

Immunohistochemical characterization of melanomas in bigenic mice containing activated Cdk4 and keratinocyte specific ablation of Retinoid-X-Receptor alpha (RXRα) protein With international consideration of Differences in Societal and Behavioral Attitudes toward Skin Cancer between Japanese American and Japanese

Creator:: Nguyen, Vananh M.
Abstract:: OVERVIEW OF INTRODUCTION - This is a combined thesis for both disciplines of BioResource Research (BRR)Interdisciplinary and International Degree (ID) Programs OSU. The first chapter encompasses the BRR research, which is a preliminary study utilizing immunohistochemical method to characterize melanomas in bigenic mice with activated Cdk4 protein and Retinoid-X-Receptor α...
Resource Type:: Presentation and Undergraduate Thesis
Full Text:: ......................................................32 3. Singaporean students in 2009 AIU Summer program shield themselves from the sun with

Differences in Societal and Behavioral Attitudes toward Skin Cancer between Japanese American and Japanese

Creator:: Nguyen, Vananh M.
Abstract:: The rate of melanoma among Asian American has been steadily increasing in the past five years, while in other Asian countries, such as Japan, the incident rate remains relatively the same. Does the culture and societal attitudes toward skin cancer make a difference in the incident rate of melanoma? This...
Resource Type:: Undergraduate Thesis
Full Text:: ......................................................32 3. Singaporean students in 2009 AIU Summer program shield themselves from the sun with

Gene expression analysis in feline injection-site sarcoma : differential expression of the ΔNp63 and TAp63 isoforms

Creator:: Dien, Thalia
Abstract:: Background Feline injection-site sarcoma (FISS) is a rare and aggressive tumor associated with vaccines, drug injections, and skin trauma in cats. The understanding of FISS remains limited, posing challenges in its diagnosis, treatment, and prevention. In this study, we analyzed the differential expression of miRNAs and their target genes in...
Resource Type:: Undergraduate Thesis

Detection and Identification of Acetaminophen (Tylenol) Metabolites using Liquid Chromatography High Resolution Mass Spectrometry (LC-HRMS/MS) Analysis

Creator:: Sanchez, Karina M.
Abstract:: Acetaminophen (APAP) is a commonly used analgesic and antipyretic drug that can cause liver injury, liver necrosis, and liver failure. APAP-induced liver failure (AILF) is associated with depletion of glutathione and the increased formation of APAP protein adducts from the toxic NAPQI metabolite. There is a hypothesized detoxifying pathway where...
Resource Type:: Undergraduate Thesis
Full Text:: Pharmacy faculty development funds. 17 Citations: 1. Sun J, Schnackenberg LK

Characterization of Selective Knockout of Thioredoxin Reductase-1 (TR1) in Mouse Melanocytes In Vivo

Creator:: Wyant, Mark B.
Abstract:: Vitiligo is a disease characterized by depigmented patches of skin. The disease is known to involve the loss of melanocytes in the basal layer of the skin in affected areas, but the underlying mechanisms are unknown. Recent evidence suggests oxidative stress and disruptions to antioxidant pathways contribute to an autoimmune...
Resource Type:: Undergraduate Thesis
Full Text:: & Redox Signaling. 2010;12(7):893–905 Boudjadi S, Chatterjee B, Sun W, Vemu P, Barr FG. The

ScholarsArchive@OSU

Functional consequences of microRNA regulation by polycyclic aromatic hydrocarbons in 3D human bronchial epithelial cells

Impact of Polycyclic Aromatic Hydrocarbons on Barrier Function Toxicity in 3D Lung Model from Normal and Asthmatic Donor Cells

Understanding polycyclic aromatic hydrocarbon (PAH) toxicity and inflammation in human bronchial epithelial cells

Enhancing Protocols to Improve Consistency Across Nanotoxicology Studies

Bacterial seed endophytes of Douglas-fir (Pseudotsuga menziesii) and their potential to confer drought tolerance

Differences in Societal and Behavioral Attitudes toward Skin Cancer between Japanese American and Japanese

Gene expression analysis in feline injection-site sarcoma : differential expression of the ΔNp63 and TAp63 isoforms

Detection and Identification of Acetaminophen (Tylenol) Metabolites using Liquid Chromatography High Resolution Mass Spectrometry (LC-HRMS/MS) Analysis

Characterization of Selective Knockout of Thioredoxin Reductase-1 (TR1) in Mouse Melanocytes In Vivo

Limit your search

Academic Affiliation

Advisor

Commencement Year

Committee Member

Creator

Contributor

Date

Decade

Degree Field

Degree Level

Degree Name

Language

License

Non-Academic Affiliation

Peer Reviewed

Resource Type

Rights Statement

Subject

Search Constraints

Search Results

Limit your search