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Comparative metabolism of the pyrrolizidine alkaloid senecionine in rat and guinea pig

Creator:: Chung, Woon-Gye
Resource Type:: Dissertation
Full Text:: would like to thank Dr. Donald Raymond Buhler for his understanding, encouragement, patience and

The effects of hexachlorophene on mitochondrial and artificial membrane systems

Creator:: Ramberg, Donald Allen
Abstract:: Hexachlorophene (HCP; 2,2'-methylenebis-(3,4,6-trichlorophenol)) was developed as an antibacterial agent but was also found to induce toxic effects in various tissues in animals and humans. Changes were found in myelinated nerve fibers and cerebral white matter. Erythrocytes are hemolysed in vitro. Oxidative phosphorylation is uncoupled by HCP at concentrations less than...
Resource Type:: Dissertation
Full Text:: artificial membrane systems AN ABSTRACT OF THE THESIS OF Donald Allen Ramberg for the degree of Doctor of

Studies on carcinogen metabolizing enzymes in the rainbow trout

Creator:: Chen, Shiu-ling
Resource Type:: Masters Thesis
Full Text:: Abstract approved: Redacted for Privacy Donald R. Buhler Both trout and mammals are susceptible to

Toxicity and in vitro metabolism of Senecio jacobaea pyrrolizidine alkaloids in the rat and mouse

Creator:: Ramsdell, Howard Scott
Abstract:: Senecio jacobaea (tansy ragwort) is a common weed in the Pacific Northwest that contains toxic pyrrolizidine alkaloids (PAs). Jacobine, the major PA in Senecio jacobaea, was incubated with rat liver microsomes and metabolites were isolated by high performance liquid chromatography (HPLC) and identified by mass spectrometric analysis. Metabolites included a...
Resource Type:: Dissertation
Full Text:: Mouse Abstract approved: D ai \- Donald R. Buhle “ r oe > Senecio

Cloning, heterologus expression, and characterization of the cytochrome P450 monooxygenases in rainbow trout (Oncorhynchus mykiss)

Creator:: Yang, Yea-Huey
Resource Type:: Dissertation
Full Text:: Trout (Oncorhynchus mykiss). Abstract approved: Donald R. Buhler Rainbow trout (Oncorhynchus mykiss

Purification, characterization and comparative properties of hepatic microsomal mixed-function oxidase enzymes from rat and rainbow trout

Creator:: Williams, David Edward
Resource Type:: Dissertation
Full Text:: FROM RAT AND RAINBOW TROUT Abstract approved: Redacted for privacy Dr. Donald R. Buhler Utilizing

Cytochrome P450 3A forms in rainbow trout (Oncorhynchus mykiss)

Creator:: Lee, Su-Jun
Resource Type:: Dissertation
Full Text:: Privacy Redacted for Privacy ACKNOWLEDGMENTS I would like to give my thanks to Dr. Donald R. Buhler

Xenobiotic biotransformation in aquatic organisms

Creator:: Schlenk, Daniel K.
Abstract:: Aquatic animals are exposed to a variety of natural and anthropogenic xenobiotics. Biotransformation of xenobiotics was examined in three aquatic animals: a primitive mollusc (chiton); a shellfish which is an important human food source (oyster); and, a lower vertebrate model for toxicological studies (rainbow trout). Since digestive glands of Cryntochiton...
Resource Type:: Dissertation
Full Text:: Abstract approved: Donald R. Buhler Aquatic animals are exposed to a variety of natural and

The influence of diet and dieldrin on the growth and body composition of underyearling rainbow trout

Creator:: Phillips, Glenn R.
Abstract:: The effects of a sublethal concentration of dieldrin (0. 2 ppb) in the water on the growth and body composition of underyearling rainbow and cutthroat trout held in aquaria and fed different rations of tubificid worms or Oregon moist pellets were studied at Oak Creek Fisheries Research Laboratory, Oregon State...
Resource Type:: Masters Thesis
Full Text:: TROUT Abstract approved: Redacted for Privacy Donald R. Buhler The effects of a sublethal

The effect of hexachlorophene and related compounds on torula yeast glucose-6-phosphate dehydrogenase and some other dehydrogenase enzymes

Creator:: Wang, Jun-Lan
Abstract:: Low concentrations of hexachlorophene (HCP) inhibit a number of pyridine nucleotide-linked dehydrogenase enzymes. The I₅₀ HCP concentrations were 105 μM for pig heart isocitrate dehydrogenase (ICD), 65 μM for horse liver alcohol dehydrogenase, 39 μM for torula yeast glucose-6-phosphate dehydrogenase (G6PD), 6.0 μM for beef heart malate dehydrogenase, and 1.6...
Resource Type:: Dissertation
Full Text:: DEHYDROGENASE ENZYMES Abstract approved: Redacted for Privacy Dr. Donald R. Buhler Low concentrations of

ScholarsArchive@OSU

Comparative metabolism of the pyrrolizidine alkaloid senecionine in rat and guinea pig

The effects of hexachlorophene on mitochondrial and artificial membrane systems

Studies on carcinogen metabolizing enzymes in the rainbow trout

Toxicity and in vitro metabolism of Senecio jacobaea pyrrolizidine alkaloids in the rat and mouse

Cloning, heterologus expression, and characterization of the cytochrome P450 monooxygenases in rainbow trout (Oncorhynchus mykiss)

Purification, characterization and comparative properties of hepatic microsomal mixed-function oxidase enzymes from rat and rainbow trout

Cytochrome P450 3A forms in rainbow trout (Oncorhynchus mykiss)

Xenobiotic biotransformation in aquatic organisms

The influence of diet and dieldrin on the growth and body composition of underyearling rainbow trout

The effect of hexachlorophene and related compounds on torula yeast glucose-6-phosphate dehydrogenase and some other dehydrogenase enzymes

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