Index Catalog // ScholarsArchive@OSU

Bacterial 16S ribosomal DNA analysis of pyrrolizidine alkaloid detoxifying enrichments from the ovine rumen

Creator:: Gray, Diane R.
Abstract:: Bacterial cultures enriched from sheep rumen fluid have demonstrated the ability to detoxify pyrrolizidine alkaloids (seneciphylline and jacobine) in tansy ragwort (Senecio jacobaea). The microbes are difficult to isolate using classical anaerobic techniques, therefore, microbes from two different enrichment cultures demonstrating similar degradation activity were identified using their 16S ribosomal...
Resource Type:: Masters Thesis
Full Text:: . Morrie Craig N Bacterial cultures enriched from sheep rumen fluid have demonstrated the ability to

Metabolism of toxic plant alkaloids in livestock : comparative studies on the hepatic metabolism of pyrrolizidine alkaloids in sheep and cattle and of ergot alkaloids in an endophyte-resistant mouse model

Creator:: Duringer, Jennifer Marie
Abstract:: The pyrrolizidine alkaloids (PAs) and ergot alkaloids are known natural toxicants found in livestock forage. These alkaloids contribute to large economic losses in livestock throughout the world. An understanding of the mechanisms of toxicity and development of better diagnostic tools for better management practices was investigated. Variability exists in the...
Resource Type:: Dissertation
Full Text:: want to thank my major professor, Dr. Craig, for supporting me and for providing me with the

Ruminal Biodegradation of Heterocyclic Toxic Compounds

Creator:: Tanaree, Dan D.
Abstract:: Cyclic nitramines are a class of compounds that include most of the commonly used explosives today. These are among the most common toxicants released into the environment as a result of human activity, generated on military ranges, battlefields, and production sites. Of these, hexahydro-1,3,5-trinitro-1,3,5- triazine (RDX) is of particular interest,...
Resource Type:: Dissertation
Full Text:: : ______________________________________________________ A. Morrie Craig Cyclic nitramines are a class of compounds that include most of the

Biotransformation of 2,4,6-trinitrotoluene by ruminal organisms

Creator:: De Lorme, Marthah J. M.
Abstract:: 2,4,6-Trinitrotoluene (TNT) has been the common munitions used in the world and is an environmental contaminant that is amendable to reductive transformation reactions. The rumen is an extremely reductive environment containing diverse microbial populations. There are 21 pure culture ruminal bacteria species in culture collection, these were tested for the...
Resource Type:: Dissertation
Full Text:: Abstract approved: ________________________________________________ A. Morrie Craig 2,4,6

Encapsulation of Ruminococcus flavefaciens using PAH and PSSS

Creator:: Nguyen, Mytrang T.
Resource Type:: Presentation
Full Text:: Mentor: Dr. A. Morrie Craig Department of Veterinary Medicine and Environmental & Molecular

Metabolism of pyrrolizidine alkaloids by ruminal microbes

Creator:: Hovermale, Jeannette Talbot
Abstract:: The plant Senecio jacobaea (tansy ragwort) produces several macrocyclic pyrrolizidine alkaloids which cause irreversible liver cirrhosis. All of the pyrrolizidine alkaloids in Senecio jacobaea are macrocyclic diesters of the necine base retronecine, with the two most predominant being seneciphylline and jacobine. Unlike horses and cattle, sheep and goats are generally...
Resource Type:: Dissertation
Full Text:: . Abstract approvecRedacted for Privacy A. Morrie Craig The plant Senecio jacobaea (tansy ragwort) produces

Exposure to the Mycotoxin Zearalenone Impairs Embryonic Development in Zebrafish

Creator:: Sidebotham, Nicole A.
Abstract:: A study was conducted to evaluate the developmental toxicity of three commonly detected mycotoxins in food (deoxynivalenol, patulin, and zearalenone) using the zebrafish (Danio rerio) model. Mycotoxin exposures were carried out at five concentrations (0.0064, 0.064, 0.64, 6.4, and 64 μM). Morphological and photomotor screenings were conducted at 24 hours...
Resource Type:: Honors College Thesis
Full Text:: : ______________________________________________________ A. Morrie Craig A study was conducted to evaluate the developmental toxicity of three

Molecular characterization of bacterial populations implicated inthe anaerobic metabolism of toxic plant alkaloids from two different experimental and environmental sources

Creator:: Rattray, Rogan MacKay
Abstract:: There have been many studies that describe the protective degradation or metabolism of potentially harmful plant toxins, such as, mimosine from Leucaena leuconcephala, pyrrolizidine alkaloids from tansy ragwort (Senecio jacobaea), oxalate and some mycotoxins by rumen microbes. There are many cases of plant-related toxicoses suffered by ruminant animals where there...
Resource Type:: Masters Thesis
Full Text:: Craig There have been many studies that describe the protective degradation or metabolism of

Correlation of endophyte toxins (ergovaline and lolitrem B) with clinical disease : fescue foot and perennial ryegrass staggers

Creator:: Tor-Agbidye, John
Abstract:: Endophytic fungi (A. coenophialum and A. lolii) which infect grasses produce ergot alkaloids that serve as the grasses' chemical defenses and enhance the vigor of the grass. Turf-type tall fescue with high endophyte levels has been deliberately developed to produce a greener, more vigorous, pest-resistant turf. Consumption of endophyte-infected grass...
Resource Type:: Masters Thesis
Full Text:: : Fescue Foot and Perennial Ryegrass Staggers Abstract Approved: Dr. A. Morrie Craig Endophytic fungi (A

A study of chronic Senecio jacobaea toxicosis in calves and ponies

Creator:: Pearson, Erwin G.
Abstract:: An experiment was designed to simulate field conditions of tansy ragwort poisoning in cattle and horses. Four calves and four ponies were fed pelleted feed containing 5% Senecio jacobaea and two ponies and two calves were used as controls. The feeding continued for two months. Following this, the chronic delayed...
Resource Type:: Masters Thesis
Full Text:: Calves and Ponies Abstract approved: Redacted for privacy //A(Morrie Craig/ An experiment was

ScholarsArchive@OSU

Bacterial 16S ribosomal DNA analysis of pyrrolizidine alkaloid detoxifying enrichments from the ovine rumen

Metabolism of toxic plant alkaloids in livestock : comparative studies on the hepatic metabolism of pyrrolizidine alkaloids in sheep and cattle and of ergot alkaloids in an endophyte-resistant mouse model

Ruminal Biodegradation of Heterocyclic Toxic Compounds

Biotransformation of 2,4,6-trinitrotoluene by ruminal organisms

Encapsulation of Ruminococcus flavefaciens using PAH and PSSS

Metabolism of pyrrolizidine alkaloids by ruminal microbes

Exposure to the Mycotoxin Zearalenone Impairs Embryonic Development in Zebrafish

Molecular characterization of bacterial populations implicated inthe anaerobic metabolism of toxic plant alkaloids from two different experimental and environmental sources

Correlation of endophyte toxins (ergovaline and lolitrem B) with clinical disease : fescue foot and perennial ryegrass staggers

A study of chronic Senecio jacobaea toxicosis in calves and ponies

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