Anaerobic digestion is a common terminal step in wastewater treatment systems and produces valuable by-products such as biogas, a combination of carbon dioxide and methane. Biogas can be used to off-set energy costs, and along with the anaerobic co-digestion of fats, oils, and greases (FOG) has been found to increase...
STEM education is delivered to K12 audiences by Pre-college Programs across the nation, many of which serve underrepresented and underserved students as part of their core missions. While there is robust attention to STEM curriculum development and college connection events in such programs, few have social-cultural aspects of learning as...
STEM education is delivered to K12 audiences by Pre-college Programs across the nation, many of which serve underrepresented and underserved students as part of their core missions. While there is robust attention to STEM curriculum development and college connection events in such programs, few have social-cultural aspects of learning as...
Infertility is an issue affecting millions of women across the globe, yet the causes are not fully understood, and treatment options are often ineffective. The evaluation of reproductive hormones has been a common tool used by fertility clinics as a way to predict the ovarian response to treatment and gain...
The use of zebrafish in behavioral neuroscience is rapidly growing. Zebrafish can be assessed for alterations in multiple behavioral endpoints, creating opportunities to use this powerful model to identify chemicals that alter behavioral phenotypes. To evaluate the utility of zebrafish for neurotoxicity research, we designed custom instrumentation to evaluate numerous...
Acetaminophen (APAP) is a commonly used analgesic and antipyretic drug that can cause liver injury, liver necrosis, and liver failure. APAP-induced liver failure (AILF) is associated with depletion of glutathione and the increased formation of APAP protein adducts from the toxic NAPQI metabolite. There is a hypothesized detoxifying pathway where...
Cell lines deficient in certain genes of the DNA mismatch repair (MMR) system show a marked resistance to the cell killing or apoptotic effects of DNA alkylating agents. The molecular mechanism for this resistance is not yet understood, but is currently of great interest because of the recent use of...