Serine transhydroxymethylase (STHM), a pyridoxal 5'-
phosphate requiring enzyme is indirectly involved in
pyrimidine deoxynucleotide metabolism. A decrease in the
activity of this enzyme could lead to altered deoxycytidine
(dC) metabolism. This study was undertaken to determine if
a vitamin B-6 deficiency affects dC metabolism. The effect
of a vitamin...
Recently, high carbohydrate diets were recommended for the
treatment of diabetes mellitus. All aspects of these diets, however,
have not been fully tested — particularly in insulin dependent
diabetes mellitus (IDDM). The present study was designed to
investigate the effects of high carbohydrate, low fat diets (HCLFD)
on blood glucose...
The purpose of this study was, first, to investigate whether there
is a vitamin B-6 requirement for carnitine synthesis and, second, to investigate
the effect of fasting on vitamin B-6 metabolism. An experimental
group of 72 rats (6 per group) were fed either a vitamin B-6 deficient
diet (-B6) (ad...
To investigate the responses of healthy adult women to two
levels of vitamin B-6, a seven week two-part experiment was conducted
with five young adults and eight middle-aged subjects. During the
four unsupplemented weeks, dietary vitamin B-6 was 2.3-2.4 mg/day.
In the final three weeks, the same diet was supplemented...
Trained male cyclists (6 in study 1, 5 in study 2) cycled to exhaustion (EXH) at
75% of VO₂ max twice; once in the non-supplemented (NS) state and once in the vitamin
B-6 (B-6)(20 mg PN) supplemented (S) state. The diet contained 2.3 mg B-6 in study 1
and 1.9...
The purpose of this study was to examine the effect of extreme exercise on vitamin B-6
metabolism and urea nitrogen. Nine men and five women completed two 5-day trials; Trial 1
(T1) included a 50-km ultramarathon on day 4 and during Trial 2 (T2) subjects were "inactive"
on day 4....