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Filtering by: Degree Field Molecular and Cellular Biology Remove constraint Degree Field: Molecular and Cellular Biology Advisor Rockey, Daniel D. Remove constraint Advisor: Rockey, Daniel D.

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  • Chlamydiae Enhance Self-Antigen Presentation in a Mechanism that is Dependent on Biosynthesis of Lipooligosaccharide

    Creator:
    Cram, Erik D.
    Abstract:
    Chlamydia is a genus of obligate intracellular bacteria that undergo a unique, biphasic developmental cycle. The infectious and metabolically inert Elementary Bodies (EBs) begin the cycle of infection by attaching and invading a host cells. Once inside, the EBs differentiate into the metabolically active, dividing Reticulate Bodies (RBs) within their...
    Resource Type:
    Dissertation
    Full Text:
    degree of Doctor of Philosophy in Molecular and Cellular Biology presented on March 23, 2016. Title

  • Using Culture-independent Genomics as a Means for Understanding Chlamydial Biology

    Creator:
    Putman, Timothy E.
    Abstract:
    The chlamydiae are a family of obligate intracellular bacteria that have a unique bi-phasic developmental cycle, unique cellular properties, and a unique set of challenges to studying its biology. While genetic manipulation is becoming routine in Chlamydia, there are significant challenges to working with this intracellular parasite. The body of...
    Resource Type:
    Dissertation
    Full Text:
      of   Doctor   of   Philosophy   in  Molecular   and   Cellular   Biology  presented

  • PCR-based Sequencing System across Chlamydia trachomatis

    Creator:
    Roetcisoender, Jake
    Abstract:
    Chlamydia trachomatis is an obligate intracellular pathogen that affects millions of people worldwide via ocular or reproductive tract infection. Despite obvious differences in site of infection, there has been shown to be high levels of sequence conservation across C. trachomatis. This high level of sequence conservation is hindered with a...
    Resource Type:
    Honors College Thesis
    Full Text:
    requirements for the degree of Honors Baccalaureate of Science in Biochemistry and Molecular Biology

  • Integration of Amino Acid Sequence and Alphafold2 Structural Predictions for Chlamydia trachomatis Polymorphic Membrane Proteins

    Creator:
    DeBrine, Abigail
    Abstract:
    Chlamydia trachomatis is an obligate intracellular bacterium that causes diseases of the eye and urogenital tract in humans. It is the cause of the sexual transmitted infection (STI) chlamydia, the most prevalent STI worldwide, and the ocular disease trachoma, the leading cause of infectious blindness. To date there is no...
    Resource Type:
    Honors College Thesis
    Full Text:
    Honors Baccalaureate of Science in Biochemistry and Molecular Biology (Honors Scholar

  • Inclusion development in cells infected with Chlamydia abortus

    Creator:
    DeBoer, Addison
    Abstract:
    Chlamydia abortus, an intracellular bacterium, spreads through flocks of sheep and goats, causing ovine enzootic abortion (OAE). Chlamydiae develop within a pathogen-modified vacuole in the host cell called the inclusion, which allows the bacteria to acquire host resources. The morphology of the inclusion varies between chlamydial species. Some species fuse...
    Resource Type:
    Honors College Thesis
    Full Text:
    degree of Honors Baccalaureate of Science in Biochemistry and Molecular Biology (Honors Scholar

  • Analyzing the molecular basis of increased enduracidin production in Streptomyces fungicidicus

    Creator:
    Herinckx, Molly A.
    Abstract:
    Enduracidin is an antibiotic produced by Streptomyces fungicidicus that is effective against Gram-positive bacteria. Previous work identified seventy-eight mutations in an S. fungicidicus strain that produces a significantly higher level of enduracidin than the wild type strain, ATCC 21013. Eleven mutations were analyzed individually to identify those that may contribute...
    Resource Type:
    Honors College Thesis
    Full Text:
    in Biochemistry and Molecular Biology presented on May 16, 2019. Title: Analyzing the molecular