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Filtering by: Creator Muehlbauer, Jeffrey D. Remove constraint Creator: Muehlbauer, Jeffrey D. Advisor Rockey, Daniel D. Remove constraint Advisor: Rockey, Daniel D.

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  • Genetic variation of Renibacterium salmoninarum genes in infected salmonids

    Creator:
    Burnett, Jeffrey R.
    Abstract:
    Renibacterium salmoninarum is the causative agent of bacterial kidney disease in both wild and farmed salmonid species worldwide. The genome of this pathogen has significant synteny to the ubiquitous, soil-dwelling Arthrobacter spp. though it is 1.9 Mb smaller, suggesting that reductive evolution has occurred. Recently, our group finished sequencing and...
    Resource Type:
    Undergraduate Thesis and Presentation

  • Using Culture-independent Genomics as a Means for Understanding Chlamydial Biology

    Creator:
    Putman, Timothy E.
    Abstract:
    The chlamydiae are a family of obligate intracellular bacteria that have a unique bi-phasic developmental cycle, unique cellular properties, and a unique set of challenges to studying its biology. While genetic manipulation is becoming routine in Chlamydia, there are significant challenges to working with this intracellular parasite. The body of...
    Resource Type:
    Dissertation
    Full Text:
     approved:  ______________________________________________________   Daniel  D.  Rockey

  • Inclusion development in cells infected with Chlamydia abortus

    Creator:
    DeBoer, Addison
    Abstract:
    Chlamydia abortus, an intracellular bacterium, spreads through flocks of sheep and goats, causing ovine enzootic abortion (OAE). Chlamydiae develop within a pathogen-modified vacuole in the host cell called the inclusion, which allows the bacteria to acquire host resources. The morphology of the inclusion varies between chlamydial species. Some species fuse...
    Resource Type:
    Honors College Thesis
    Full Text:
    :_____________________________________________________ Daniel D. Rockey Chlamydia abortus, an intracellular bacterium, spreads through flocks of

  • Chromosomal Recombination Targets in Chlamydial Lateral Gene Transfer In Vitro

    Creator:
    Kim, Debbie Blue
    Abstract:
    Background: Lateral gene transfer (LGT) among C. trachomatis strains is common, both in isolates generated in the laboratory and those examined directly from patients. This is a challenging concept because there are very few examples of recent acquisition of foreign DNA by Chlamydia spp. There is no understanding of the...
    Resource Type:
    Honors College Thesis
    Full Text:
    Daniel D. Rockey Background: Lateral gene transfer (LGT) among C. trachomatis strains is common

  • Chlamydiae Enhance Self-Antigen Presentation in a Mechanism that is Dependent on Biosynthesis of Lipooligosaccharide

    Creator:
    Cram, Erik D.
    Abstract:
    Chlamydia is a genus of obligate intracellular bacteria that undergo a unique, biphasic developmental cycle. The infectious and metabolically inert Elementary Bodies (EBs) begin the cycle of infection by attaching and invading a host cells. Once inside, the EBs differentiate into the metabolically active, dividing Reticulate Bodies (RBs) within their...
    Resource Type:
    Dissertation
    Full Text:
    AN ABSTRACT OF THE DISSERTATION OF Erik D. Cram for the

  • PCR-based Sequencing System across Chlamydia trachomatis

    Creator:
    Roetcisoender, Jake
    Abstract:
    Chlamydia trachomatis is an obligate intracellular pathogen that affects millions of people worldwide via ocular or reproductive tract infection. Despite obvious differences in site of infection, there has been shown to be high levels of sequence conservation across C. trachomatis. This high level of sequence conservation is hindered with a...
    Resource Type:
    Honors College Thesis
    Full Text:
    serovars (A, B, Ba, C, D, Da, E, F, G, Ga, H, I, Ia, J, K, L1, L2, L2a, L2b, L2c, and L3), C. trachomatis

  • Inclusion Fusion and Genetic Recombination: Bridging the Gap Between the Chlamydiae

    Creator:
    Garvin, Lotisha E.
    Abstract:
    Chlamydia is an obligate intracellular bacterial pathogen that causes a variety of disease in animals and humans worldwide. Veterinary chlamydial pathogens can lead to chronic infections and serious consequences that result in millions of dollars of losses in animals and resources in the agricultural industry in countries that rear ruminants....
    Resource Type:
    Dissertation
    Full Text:
    Abstract approved: Daniel D. Rockey