Neonatal jaundice secondary to hyperbilirubinemia occurs in 60% of all term newborns and nearly all preterm newborns in the US. Severe cases of this may lead to chronic encephalopathy, neurologic deficits, and, in some cases, death. Intensive blue light phototherapy involves irradiation of a patient with high intensity light and...
Cryopreservation depends on the equilibration of cells with high concentration of cryoprotective agents (CPAs). However, the addition of CPAs can induce damages to the cells. One of the damages is due to too much shrinkage or swell of the cell volume which lead to the cell death during the addition...
In the last decade, there has been renewed interest in the use of granulocyte transfusions to treat infections in individuals with compromised immune systems. However, granulocytes only remain functional for about a day after isolation and this short shelf life is a significant drawback. Cryopreservation would allow long term storage...
Cryopreservation of adherent cells may be advantageous for cell types that are difficult to
preserve in suspension or when it is necessary to preserve characteristics of the adherent cultured cells. Vitrification is a promising procedure for the preservation of adherent cells that prevents ice crystal formation and the resulting dissociation...
Due to the many advances in the areas of biotechnology and medicine, the need for long-
term storage and stabilization of biological materials is rapidly increasing. The field of
biopreservation is attempting to address these issues by finding ways to maintain the integrity and
functionality of proteins, cells, and organs...