Index Catalog // ScholarsArchive@OSU

Investigating the Interplay of Age, Zinc Status, and the Gut Microbiome on Gut Health

Creator:: Vasudevan, Anusha
Abstract:: Zinc is an important micronutrient involved in many cellular processes, including those part of immune function; however, about 15% of the US population is at risk for marginal zinc deficiency. This can lead to immune system complications including the generation of inflammatory cytokines. Aging is another factor that worsens the...
Resource Type:: Honors College Thesis

The Effect of Zinc Status and Age on Liver Health in Mice

Creator:: Braun, Kendra N.
Abstract:: Age-related diseases have been associated with chronic inflammation and impaired immune response, one of the hallmarks of aging. Aging individuals also have a higher susceptibility to zinc deficiency. The effects of zinc deficiency share many commonalities with the effects of aging on the immune system and zinc deficiency may be...
Resource Type:: Honors College Thesis

Arsenic and Zinc Deficiency Induced Changes in Pancreatic Beta Cells

Creator:: Cao, Annie L.
Abstract:: Pancreatic beta cells produce and release insulin, a vital hormone that regulates blood glucose levels, and their dysfunction contributes to the development of diabetes mellitus. Dietary zinc deficiency and exposure to the toxicant inorganic arsenic have both independently been associated with diabetes, although the effects of their combination on pancreatic...
Resource Type:: Honors College Thesis

Effects of low zinc status and arsenic exposure in mice

Creator:: Chase, Tyler, Wong, Carmen P., and Ho, Emily
Abstract:: During fall term of 2015 and winter and spring term of 2016 I assisted in research within Dr. Emily Ho’s lab. The project that I assisted in looked at the effects of low zinc status and arsenic exposure in mice. Zinc is an essential micronutrient involved in numerous cellular processes...
Resource Type:: Poster

The Effect of Intracellular Zinc Concentration on Immune Activation and Proinflammatory Response in THP-1 Monocytes

Creator:: Rinaldi, Nicole A.
Abstract:: Zinc is an essential micronutrient required for many cellular functions, including the development and function of the immune system. The biological consequences of zinc deficiency illustrate the significance of zinc in human health. Zinc deficiency has been shown to cause the dysregulation of both innate and adaptive immune responses, as...
Resource Type:: Undergraduate Thesis and Presentation

Plasma metabolites altered by sulforaphane in humans

Creator:: Kelsey, Kimberly J., Atwell, Lauren L., Clarke, John D., Hsu, Anna, Bella, Deborah, Stevens, Jan F., Dashwood, Roderick H., Williams, David E., and Ho, Emily
Abstract:: Consuming cruciferous vegetables such as broccoli sprouts, kale, Brussels sprouts, and bok choy is associated with several health benefits, such as a decreased risk of certain cancers. Cruciferous vegetables contain the glucosinolate, glucoraphanin (GFN). Cutting, chopping or chewing these vegetables releases the enzyme myrosinase, which transforms GFN into sulforaphane (SFN)....
Resource Type:: Poster

Sulforaphane Decreases Ezh2 Expression in PC3 Prostate Cancer Cells

Creator:: Black, Chelsea, Watson, Greg, and Ho, Emily
Abstract:: Prostate cancer is one of the most prevalent types of cancer in the U.S. and is among the leading causes of death in men of all races. One predictor of advanced prostate cancer and aggressive tumor behavior is the overexpression of the histone methyl transferase EZH2. EZH2 functions in the...
Resource Type:: Poster

Sulforaphane Decreases Ezh2 Expression in PC3 Prostate Cancer Cells

Creator:: Black, Chelsea and Watson, Greg
Abstract:: Prostate cancer is one of the most prevalent types of cancer in the U.S. and is among the leading causes of death in men of all races. One predictor of advanced prostate cancer and aggressive tumor behavior is the overexpression of the histone methyl transferase EZH2. EZH2 functions in the...
Resource Type:: Poster

Difference in prostate cancer rates between the United States and Spain : effect of vitamin D

Creator:: Marvel, Kathryn
Abstract:: Prostate cancer is the most commonly diagnosed cancer in men, but rates around the world vary greatly. Americans have the highest incidence rates in the world, 4 to 5 times those of Spain. The hypothesis of this thesis was that vitamin D metabolism is a factor in prostate cancer development...
Resource Type:: Honors College Thesis

ScholarsArchive@OSU

Investigating the Interplay of Age, Zinc Status, and the Gut Microbiome on Gut Health

The Effect of Zinc Status and Age on Liver Health in Mice

Arsenic and Zinc Deficiency Induced Changes in Pancreatic Beta Cells

Effects of low zinc status and arsenic exposure in mice

The Effect of Intracellular Zinc Concentration on Immune Activation and Proinflammatory Response in THP-1 Monocytes

Plasma metabolites altered by sulforaphane in humans

Sulforaphane Decreases Ezh2 Expression in PC3 Prostate Cancer Cells

Sulforaphane Decreases Ezh2 Expression in PC3 Prostate Cancer Cells

Difference in prostate cancer rates between the United States and Spain : effect of vitamin D

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