Index Catalog // ScholarsArchive@OSU

Analysis of the prevalence of type 2 diabetes in Mexicans and Mexican Americans

Creator:: Sobolik, Julia Silva
Abstract:: Non-insulin dependent diabetes mellitus (NIDDM), commonly known as type 2 or delayed onset diabetes, is a recognized growing global epidemic, which is connected to cultural and behavioral factors, such as diet, exercise, obesity, and genetics. In a recent survey of both men and women in Mexico City, the prevalence of...
Resource Type:: Honors College Thesis

Antisense Antibiotics

Creator:: Mitev, Georgi Mitko
Abstract:: Two different types of Phosphorodiamidate Morpholino Oligomers (PMOs) were used to inhibit growth in pure cultures of Salmonella enterica serovar typhimurium and in mouse macrophages infected with S. typhimurium. Both PMOs were 11 bases long and complementary to bases 6-16 of acyl carrier protein mRNA. A membrane-penetrating peptide, (RXR)4XB, was...
Resource Type:: Honors College Thesis

Chemical screening of the secondary metabolites of Streptomyces cellulosae

Creator:: Fifield, Rory E.J.
Abstract:: The purpose of this project was to isolate gabosines and other compounds through chemical screening of secondary metabolites of Streptomyces cellulosae subsp. griseorubiginoses strain S1096. Two different media were used to cultivate S. cellulosae. The first contained soybean and mannitol. The other contained oatmeal and trace element solution. After cultivation...
Resource Type:: Honors College Thesis

Effect of Perinatal Low Protein Diet on the Expression of Renal Organic Cation Transporter 2 and Novel Organic Cation Transporter 2 in Adult Rats

Creator:: Nguyen, Paulina M.
Abstract:: Studies have established that there is a greater risk for onset of adult metabolic syndrome disease such as diabetes mellitus, hypertension, hyperlipidemia, and obesity in subjects born with low birth weight (LBW). Undernourished fetuses make adaptions that result in structurally, morphologically, and functionally altered organs. In terms of drug pharmacokinetics,...
Resource Type:: Honors College Thesis

Genomic identification of candidate inclusion membrane proteins in Chlamydial species and microscopic analysis

Creator:: Blake, Nathanael A.
Abstract:: The Chlamydiaceae are a family of obligate intracellular bacteria with a unique biphasic developmental cycle. The replicating, metabolically active, intracellular phase bacteria (RBs) grow within a cellular vacuole know as the inclusion. Since the proteins the Chlamydiaceae secrete into this membrane are the means of host/parasite interaction, they have long...
Resource Type:: Honors College Thesis

Heart Disease Knowledge, Awareness, and Perceived Risk in Oregon State University Students

Creator:: Hirsch, Lindsay N.
Abstract:: Cardiovascular disease (CVD) is the leading cause of death for both men and women in the U.S. but is often thought of as a man’s disease. Women with CVD, however, suffer poorer health outcomes due to previous education of stereotypically “male” signs and symptoms of heart attacks, despite the fact...
Resource Type:: Honors College Thesis

Identification of Small Molecule Inhibitors of the Staphylococcus aureus Sortase A Enzyme

Creator:: Bateman, Katherine B.
Abstract:: The Sortase A (SrtA) enzyme is a potential target for a new class of anti-infective drugs because it is responsible for anchoring virulence factors to the surface of pathogenic, Gram-positive bacteria such as Staphylococcus aureus. High throughput screening yielded low molecular weight compounds that inhibit purified SrtA from S. aureus....
Resource Type:: Honors College Thesis

Investigating the age-related loss of endoplasmic reticulum stress response

Creator:: Fallahi, Anahita
Abstract:: The endoplasmic reticulum (ER) is a crucial organelle in the cell where protein folding and processing occurs, and conditions that negatively affect ER functions are highly detrimental to the cell. The accumulation of unfolded/misfolded proteins in the ER leads to a condition known as ER Stress. The ER has developed...
Resource Type:: Honors College Thesis

Investigation of the roles of viral proteinases in the vaccinia virus life cycle

Creator:: Page, Jessica M.
Abstract:: An inducible, mutant virus, designated vvtetO:I7L/G1L, was used to study the morphogenic proteolysis step of the vaccinia virus life cycle. The vvtetO:I7L/G1L controlled the expression of two genes, I7L, a cysteine proteinase, and G1L, a putative metalloproteinase. These proteins are involved in the maturation of viral core proteins, p4a, p4b,...
Resource Type:: Honors College Thesis

Localization of the CB1 receptor in the brain of Taricha granulosa

Creator:: Aubert, Jolene E.
Abstract:: The psychoactive component of marijuana, A9-tetrahydrocannabinol (THC), is known to have effects in humans that are mediated by the cannabinoid receptor (CB 1). Although a great deal of research has been done to confirm the interaction of exogenous cannabinoids with the CB 1 receptor, little is known about the receptor's...
Resource Type:: Honors College Thesis

ScholarsArchive@OSU

Analysis of the prevalence of type 2 diabetes in Mexicans and Mexican Americans

Antisense Antibiotics

Chemical screening of the secondary metabolites of Streptomyces cellulosae

Effect of Perinatal Low Protein Diet on the Expression of Renal Organic Cation Transporter 2 and Novel Organic Cation Transporter 2 in Adult Rats

Genomic identification of candidate inclusion membrane proteins in Chlamydial species and microscopic analysis

Heart Disease Knowledge, Awareness, and Perceived Risk in Oregon State University Students

Identification of Small Molecule Inhibitors of the Staphylococcus aureus Sortase A Enzyme

Investigating the age-related loss of endoplasmic reticulum stress response

Investigation of the roles of viral proteinases in the vaccinia virus life cycle

Localization of the CB1 receptor in the brain of Taricha granulosa

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