Studies have established that there is a greater risk for onset of adult metabolic syndrome disease such as diabetes mellitus, hypertension, hyperlipidemia, and obesity in subjects born with low birth weight (LBW). Undernourished fetuses make adaptions that result in structurally, morphologically, and functionally altered organs. In terms of drug pharmacokinetics,...
The Chlamydiaceae are a family of obligate intracellular bacteria with a unique biphasic developmental cycle. The replicating, metabolically active, intracellular phase bacteria (RBs) grow within a cellular vacuole know as the inclusion. Since the proteins the Chlamydiaceae secrete into this membrane are the means of host/parasite interaction, they have long...
Tomato is considered to be one of the most important vegetables for its value as a source
of nutrients and antioxidants, and as a model crop for biological research, including seed
biology. In this thesis, tissue-specific gene expression and its regulation in tomato seeds
were analyzed to understand the mechanisms...
The endoplasmic reticulum (ER) is a crucial organelle in the cell where protein folding and processing occurs, and conditions that negatively affect ER functions are highly detrimental to the cell. The accumulation of unfolded/misfolded proteins in the ER leads to a condition known as ER Stress. The ER has developed...
The purpose of this project was to isolate gabosines and other compounds through chemical screening of secondary metabolites of Streptomyces cellulosae subsp. griseorubiginoses strain S1096. Two different media were used to cultivate S. cellulosae. The first contained soybean and mannitol. The other contained oatmeal and trace element solution. After cultivation...