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Filtering by: Creator Freilich, Michael H. Remove constraint Creator: Freilich, Michael H. Committee Member Freitag, Michael Remove constraint Committee Member: Freitag, Michael Degree Name Honors Bachelor of Science (H.B.S.) Remove constraint Degree Name: Honors Bachelor of Science (H.B.S.)

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  • Generation of expression plasmids to study the function of the PRC2 subunit Suz12 in Fusarium graminearum

    Creator:
    Park, Catherine
    Abstract:
    The Polycomb Repressive Complex 2 (PRC2) catalyzes genome transcription repression through the methylation of lysine residue 27 in the amino terminal region of histone 3 (H3K27me1/2/3) [2], [7]. PRC2 is made up of three highly conserved core subunits: Kmt6, Eed, and Suz12. Accurate distribution of PRC2 is essential for proper...
    Resource Type:
    Honors College Thesis
    Full Text:
    Fusarium graminearum. Abstract approved:_____________________________________________________ Michael

  • Investigating Local Energy Compensation of Adjacent RNA Secondary Structures in the bpRNA-1m Database

    Creator:
    Cornwell-Arquitt, Robert L.
    Abstract:
    Non-coding ribonucleic acid (ncRNA) is of interest for its diverse roles in cell and viral biology. RNA molecules vary greatly in terms of size, structure, and function. In recent years, the modification of existing RNA structures has been used for biochemical methods of enormous impact including CRISPR and RNAi methods....
    Resource Type:
    Honors College Thesis
    Full Text:
    _____________________________________________________________________ Michael Freitag, Committee Member, representing Biochemistry and Biophysics

  • Inclusion development in cells infected with Chlamydia abortus

    Creator:
    DeBoer, Addison
    Abstract:
    Chlamydia abortus, an intracellular bacterium, spreads through flocks of sheep and goats, causing ovine enzootic abortion (OAE). Chlamydiae develop within a pathogen-modified vacuole in the host cell called the inclusion, which allows the bacteria to acquire host resources. The morphology of the inclusion varies between chlamydial species. Some species fuse...
    Resource Type:
    Honors College Thesis
    Full Text:
    _____________________________________________________________________ Michael Freitag, Committee Member, representing Biochemistry and Biophysics

  • Regulation of the Pantoea agglomerans type III secretion system by plant-exuded sugars

    Creator:
    Bacher, Daniel
    Abstract:
    Pantoea agglomerans pathovar betae (Pab) is a bacterium that causes galls on the roots of beet plants, resulting in reduced marketability of beet roots and crop loss. Pab uses a type III secretion system (T3SS) to infect and cause galls on beets. The T3SS is a molecular syringe-like structure that...
    Resource Type:
    Honors College Thesis
    Full Text:
    _____________________________________________________________________ Michael Freitag, Committee Member, representing Biochemistry and Biophysics

  • Bioactivity Screening and Gene Activation Strategies in Fungi

    Creator:
    Coddington, Nathan C.
    Abstract:
    Natural products from plants, bacteria, and fungi play an important role in society. Over the last 35 years, natural products and their derivatives have inspired over 60% of all FDA approved small-molecule drugs, and are among the top prescribed therapeutics.1-2 Fleming’s discovery of the fungal antibiotic penicillin started the “Golden...
    Resource Type:
    Honors College Thesis
    Full Text:
    Michael Freitag, Committee Member, representing Biochemistry and Biophysics George F. Neuhaus