Search Constraints

Start Over
Filtering by: Creator Freilich, Michael H. Remove constraint Creator: Freilich, Michael H. Committee Member Freitag, Michael Remove constraint Committee Member: Freitag, Michael

Search Results

  • Generation of expression plasmids to study the function of the PRC2 subunit Suz12 in Fusarium graminearum

    Creator:
    Park, Catherine
    Abstract:
    The Polycomb Repressive Complex 2 (PRC2) catalyzes genome transcription repression through the methylation of lysine residue 27 in the amino terminal region of histone 3 (H3K27me1/2/3) [2], [7]. PRC2 is made up of three highly conserved core subunits: Kmt6, Eed, and Suz12. Accurate distribution of PRC2 is essential for proper...
    Resource Type:
    Honors College Thesis
    Full Text:
    Fusarium graminearum. Abstract approved:_____________________________________________________ Michael

  • Toxicity of Fungal Pigments from Chlorociboria spp. and Scytalidium spp.

    Creator:
    Almurshidi, Badria H.
    Abstract:
    Commercial methodologies for producing fungal pigments are of worldwide interest due to the desire to move away from synthetic dyes. Chlorociboria species and Scytalidium species have been reported to produce sufficient yields of pigments for commercial production and have attracted special attention because of their use in spalted wood applications....
    Resource Type:
    Masters Thesis
    Full Text:
    ABSTRACT OF THE THESIS OF Badria H. Almurshidi for the degree of Master of Science in Wood Science

  • Identifying the Enzymes Responsible for Reduction of Doxorubicin to its Cardiotoxic Metabolite Doxorubicinol using a Novel Immunoclearing Approach

    Creator:
    Breysse, Daniel H.
    Abstract:
    Doxorubicin is a widely used cancer therapeutic, but its effectiveness is limited by cardiotoxic side effects. Evidence suggests cardiotoxicity is due not to doxorubicin, but rather its metabolite, doxorubicinol. Identification of the enzymes responsible for doxorubicinol formation is important in developing strategies to prevent cardiotoxicity. In this study, the contributions...
    Resource Type:
    Masters Thesis
    Full Text:
    ). Primary antibody incubations were for at least 2 h at 25°C, using a 1:1000 dilution of raw antiserum or

  • Characterization of the pathogenicity and phylogeny of members of the Rhodococcus genus

    Creator:
    Creason, Allison L.
    Abstract:
    Plant pathogenic Rhodococcus species are persistent pathogens able to cause severe growth deformities on a large range of hosts. The most well studied species, R. fascians is predicted by current models to synthesize a mixture of cytokinins that act to directly perturb the hosts' hormone balances, which results in abnormal...
    Resource Type:
    Dissertation
    Full Text:
    Rhodococcus Genus. Abstract approved: ______________________________________________________ Jeff H

  • Investigating Local Energy Compensation of Adjacent RNA Secondary Structures in the bpRNA-1m Database

    Creator:
    Cornwell-Arquitt, Robert L.
    Abstract:
    Non-coding ribonucleic acid (ncRNA) is of interest for its diverse roles in cell and viral biology. RNA molecules vary greatly in terms of size, structure, and function. In recent years, the modification of existing RNA structures has been used for biochemical methods of enormous impact including CRISPR and RNAi methods....
    Resource Type:
    Honors College Thesis
    Full Text:
    _____________________________________________________________________ Michael Freitag, Committee Member, representing Biochemistry and Biophysics

  • Growth, morphology, and in vitro development of transgenic poplars with RNAi-inhibited PtDDM1-1/2 gene expression

    Creator:
    Zhu, Ruoqing
    Abstract:
    Epigenetic mechanisms are important for control of plant development, and may play a particularly important role in trees given their long life cycles and distinctive and stable tissue types. To help understand the role of epigenetics in tree development, we produced transgenic poplars with reduced activity of the DDM1 genes,...
    Resource Type:
    Masters Thesis
    Full Text:
    genomic cytosine methylation. Dr. Michael Freitag helped to design the overall project. Dr. Steven H

  • Inclusion development in cells infected with Chlamydia abortus

    Creator:
    DeBoer, Addison
    Abstract:
    Chlamydia abortus, an intracellular bacterium, spreads through flocks of sheep and goats, causing ovine enzootic abortion (OAE). Chlamydiae develop within a pathogen-modified vacuole in the host cell called the inclusion, which allows the bacteria to acquire host resources. The morphology of the inclusion varies between chlamydial species. Some species fuse...
    Resource Type:
    Honors College Thesis
    Full Text:
    _____________________________________________________________________ Michael Freitag, Committee Member, representing Biochemistry and Biophysics

  • The role of innate immunity in cnidarian-dinoflagellate symbiosis

    Creator:
    Poole, Angela Z.
    Abstract:
    Cnidarians, such as corals and sea anemones serve as hosts to a variety of organisms including symbiotic dinoflagellates, bacteria, virus, and apicomplexans. As corals are vital to the health and productivity of the reef ecosystem it is important to understand how these organisms interact with each component of the holobiont....
    Resource Type:
    Dissertation
    Full Text:
    and teaching endeavors. I would also like to thank Eli Meyer, Michael Freitag, Mike Blouin, Kathy

  • Regulation of the Pantoea agglomerans type III secretion system by plant-exuded sugars

    Creator:
    Bacher, Daniel
    Abstract:
    Pantoea agglomerans pathovar betae (Pab) is a bacterium that causes galls on the roots of beet plants, resulting in reduced marketability of beet roots and crop loss. Pab uses a type III secretion system (T3SS) to infect and cause galls on beets. The T3SS is a molecular syringe-like structure that...
    Resource Type:
    Honors College Thesis
    Full Text:
    _____________________________________________________________________ Michael Freitag, Committee Member, representing Biochemistry and Biophysics

  • Anaerobic biodegradation of the cyclic nitramines, RDX and HMX, by ovine ruminal microbes

    Creator:
    Eaton, Hillary L.
    Abstract:
    Cyclic nitramines released into all environmental compartments through anthropogenic activities are toxic and possibly carcinogenic and mutagenic. Soils on military ranges, located throughout the world in various climatic regions and close to human activities, are especially susceptible to cyclic nitramine contamination. The properties of soils on military ranges will directly...
    Resource Type:
    Dissertation
    Full Text:
    similar compound, in 4 h. In this study, RDX incubated in whole ovine rumen fluid was nearly eliminated