Index Catalog // ScholarsArchive@OSU

Towards Resolving Functional and Evolutionary Mysteries of the Large and Heterozygous Genome of Hop (Humulus lupulus) and the Cannabaceae Family Using Genomic Data Science

Creator:: Padgitt-Cobb, Lillian K.
Abstract:: Hop (Humulus lupulus L. var. lupulus) is a diploid, dioecious plant with an extensive history of cultivation and use in brewing, as a textile, and for its therapeutic properties. Hop is prized for its ability to produce a variety of aromatic and flavor compounds, as well as compounds with anti-microbial...
Resource Type:: Dissertation

Investigating Local Energy Compensation of Adjacent RNA Secondary Structures in the bpRNA-1m Database

Creator:: Cornwell-Arquitt, Robert L.
Abstract:: Non-coding ribonucleic acid (ncRNA) is of interest for its diverse roles in cell and viral biology. RNA molecules vary greatly in terms of size, structure, and function. In recent years, the modification of existing RNA structures has been used for biochemical methods of enormous impact including CRISPR and RNAi methods....
Resource Type:: Honors College Thesis
Full Text:: . In Figure 2A, base-paired, helical stem segments have stabilizing negative ΔG values and the

Investigating Transcriptional Control of Specialized Gene Expression in Plants

Creator:: Fraser, Valerie N.
Abstract:: Specialized or secondary metabolism is a collection of pathways and small molecules that, while beneficial to an organism, are not strictly necessary for survival. Plants use secondary metabolites to, among other things, attract pollinators, defend against biotic and abiotic stressors, and form symbioses. Natural products from plants have seen an...
Resource Type:: Dissertation
Full Text:: retired. To each of my committee members—Dr. John Fowler, Dr. Jeffrey Anderson, Dr. Michael Freitag

Inclusion development in cells infected with Chlamydia abortus

Creator:: DeBoer, Addison
Abstract:: Chlamydia abortus, an intracellular bacterium, spreads through flocks of sheep and goats, causing ovine enzootic abortion (OAE). Chlamydiae develop within a pathogen-modified vacuole in the host cell called the inclusion, which allows the bacteria to acquire host resources. The morphology of the inclusion varies between chlamydial species. Some species fuse...
Resource Type:: Honors College Thesis
Full Text:: DMEM to the desired concentration. The plates were centrifuged for one hour at 931 x g. The media was

Chlamydiae Enhance Self-Antigen Presentation in a Mechanism that is Dependent on Biosynthesis of Lipooligosaccharide

Creator:: Cram, Erik D.
Abstract:: Chlamydia is a genus of obligate intracellular bacteria that undergo a unique, biphasic developmental cycle. The infectious and metabolically inert Elementary Bodies (EBs) begin the cycle of infection by attaching and invading a host cells. Once inside, the EBs differentiate into the metabolically active, dividing Reticulate Bodies (RBs) within their...
Resource Type:: Dissertation

Developmental toxicity of polycyclic aromatic hydrocarbons : defining mechanisms with systems-based transcriptional profiling

Creator:: Goodale, Britton C.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous in the environment as components of fossil fuels and by-products of combustion. Defining toxicity mechanisms for this large family of multi-ring structures and substituted derivatives is a substantial challenge. Several PAHs, such as benzo(a)pyrene (BaP), are mutagenic, toxic to wildlife, and classified as probable...
Resource Type:: Dissertation
Full Text:: Freitag, Kim Anderson, Barbara Taylor and Jeffrey Greenwood for their wisdom and guidance of this

Roles of homeodomain transcription factors during organogenesis

Creator:: Xu, Jun
Abstract:: The spatial and temporal patterning of sequence specific transcription factors (SSTFs) contributes to cell type specification and organ formation during embryogenesis. Homeodomain transcription factors are evolutionally conserved among invertebrate and vertebrate animals. They are responsible for body segmentation and organogenesis. Lbx1 and Pitx2 both are homeodomain transcription factors contributing to...
Resource Type:: Dissertation
Full Text:: M, Qian YQ, Otting G, Muller M, Gehring W, Wuthrich K (1993) Determination of the nuclear magnetic

Genome-enabled discovery and characterization of type III effector-encoding genes of plant symbiotic bacteria

Creator:: Kimbrel, Jeffrey A.
Abstract:: Symbiosis is the close and protracted interaction between organisms. The molecular interactions that occur during symbiosis are complex with multiple barriers that must be overcome. Many Gram-negative, host-associated bacteria use a type III secretion system to mediate associations with their eukaryotic hosts. This secretion system is a specialized apparatus for...
Resource Type:: Dissertation
Full Text:: DISSERTATION OF Jeffrey A. Kimbrel for the degree of Doctor of Philosophy in Molecular and Cellular

Transcriptomic analysis using high-throughput sequencing and DNA microarrays

Creator:: Fox, Samuel E.
Abstract:: Transcriptomics and gene expression profiling enables the elucidation of the genetic response of an organism to various environmental cues. Transcriptomics enables the deciphering of differences between two closely related organisms to the same environment and in contrast, enables the elucidation of genetic responses of the same organism to different environmental...
Resource Type:: Dissertation

Prostate cancer prevention with broccoli : from cellular to human studies

Creator:: Clarke, John D.
Abstract:: Prostate cancer is the second leading cause of cancer related death in American men. Epidemiologic studies suggest that cruciferous vegetable intake may lower the risk for many cancers, including prostate and colon. Isothiocyanates (ITC) are phytochemicals derived from cruciferous vegetables such as broccoli, Brussels sprouts, cauliflower, and cabbage that may...
Resource Type:: Dissertation
Full Text:: of broccoli extracts (equivalent to ~1.2 g dry weight broccoli) resulted in an induction of GSTA1

ScholarsArchive@OSU

Towards Resolving Functional and Evolutionary Mysteries of the Large and Heterozygous Genome of Hop (Humulus lupulus) and the Cannabaceae Family Using Genomic Data Science

Investigating Local Energy Compensation of Adjacent RNA Secondary Structures in the bpRNA-1m Database

Investigating Transcriptional Control of Specialized Gene Expression in Plants

Inclusion development in cells infected with Chlamydia abortus

Chlamydiae Enhance Self-Antigen Presentation in a Mechanism that is Dependent on Biosynthesis of Lipooligosaccharide

Developmental toxicity of polycyclic aromatic hydrocarbons : defining mechanisms with systems-based transcriptional profiling

Roles of homeodomain transcription factors during organogenesis

Genome-enabled discovery and characterization of type III effector-encoding genes of plant symbiotic bacteria

Transcriptomic analysis using high-throughput sequencing and DNA microarrays

Prostate cancer prevention with broccoli : from cellular to human studies

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