Index Catalog // ScholarsArchive@OSU

Investigation of cis-acting RNA element role in bovine viral diarrhea virus replication

Creator:: Ly, David
Abstract:: Bovine viral diarrhea virus (BVDV) is an enveloped, single-stranded positive-sense RNA virus. The BVDV genome is about 12.5 kb long and consists of a single open reading frame (ORF) flanked by untranslated regions at the 5' and 3' ends (5'-UTR and 3'- UTR, respectively). To investigate the role of cis-sequences...
Resource Type:: Masters Thesis
Full Text:: Abstract approved: Ling Jin Bovine viral diarrhea virus (BVDV) is an enveloped, single-stranded

Interaction of the Respiratory Syncytial Virus Matrix Protein and the Cellular Adaptor Protein Complex 3µ Subunit

Creator:: Ward, Casey J.
Abstract:: Respiratory Syncytial Virus (RSV) is a leading cause of bronchopneumonia in infants and elderly. Knowledge of viral and host protein interactions is important for better understanding of the viral pathogenesis and may lead to development of novel therapeutic drugs. Here, we show that RSV Matrix (M) protein interacts with cellular...
Resource Type:: Honors College Thesis
Full Text:: Anne-Marie Girgard. I would also like to thank my committee, Dr. Manoj Pastey, Dr. Ling Jin, and

Impact of Unfolded Protein Response, USP14, and NEDD8 Inhibitors Upon Antigen Presentation in SaI/Ak and 4T1 Tumor Cell Lines

Creator:: Godil, Jamila A.
Abstract:: Antigen presentation is a mechanism used by cells to present peptides on the cell surface. Peptides, derived from both viral or self-proteins are presented on the cell surface by MHC Class I molecules to be recognized and detected by cytotoxic T cells. T cells comprise the defense system to protect...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Ling Jin, Committee Member, representing Biomedical Sciences

Systemically Delivered Magnetic Hyperthermia for Cancer Treatment

Creator:: Albarqi, Hassan Ahmad M.
Abstract:: Despite advances in treatment, cancer remains among the leading causes of death in the world. Progress in the treatment of metastatic cancers was seen with chemotherapy and radiotherapy, however, the major drawbacks of conventional cancer therapies are limited efficacy and severe side effects. Magnetic fluid hyperthermia (MFH) is a new...
Resource Type:: Dissertation
Full Text:: Alani, Gaurav Sahay, and Ling Jin for serving on my thesis committee and their guidance. Special

Gene expression in the peripartum canine placenta

Creator:: Fellows, Elizabeth Jane
Abstract:: This research investigated gene expression in the canine placenta during the peripartum period. Previous studies have recognized molecular changes that occur in the placenta around the time of placental release in other species, but no study has looked at gene expression in the late gestation canine placenta. Of particular significance...
Resource Type:: Masters Thesis
Full Text:: .........................................................108 Appendix H Expression of Selected Candidate Genes in Canine Chorioallantois Tissue Using Real

Effects of selenium supplementation during different trimesters of pregnancy on non-specific humoral immunity of pregnant beef cows and persistence of antibodies in their newborn calves

Creator:: Thompson-Hernandez, Ian
Abstract:: Immunosuppression during the periparturient period leads to increased susceptibility to infectious diseases in beef cows. Newborn calves rely on passive transfer of antibodies from their mothers at birth for protection against diseases in the first two months of age. It is unknown if supranutritional Se supplementation of cows during pregnancy...
Resource Type:: Honors College Thesis
Full Text:: ). Plates were incubated for 1 h at room temperature. After incubation, plates were washed 3 times in

Multiplex real-time PCR in the detection and differentiation of bovine respiratory disease pathogens

Creator:: Zulauf, Brian J.
Abstract:: Bovine respiratory syncytial virus (BRSV), bovine viral diarrhea (BVD) and bovine parainfluenza virus Type 3 (BPI3) are ubiquitous respiratory pathogens of cattle, which contribute to causation of bovine respiratory disease complex. As these respiratory viral pathogens cause very similar clinical symptoms, differential diagnosis of the pathogens is required in one...
Resource Type:: Masters Thesis
Full Text:: keep everything on track. Thank you to my wonderful graduate committee (Jean Hall, Ling Jin and Becky

Bacterial and Host Factors Contributing to Mycobacterium avium subspecies paratuberculosis Persistent Infection

Creator:: Phillips, Ida L.
Abstract:: Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of Johne’s disease, a chronic granulomatous enteritis that plagues domestic and wild ruminants globally. During the silent stages of Johne’s disease, infected animals intermittently shed bacteria for years prior to clinical diagnosis during advanced disease stages. This strategy allows MAP to...
Resource Type:: Dissertation

Inactivation of Clostridium perfringens in Meat Products

Creator:: Alnoman, Maryam M.
Abstract:: Clostridium perfringens type A strains are one of the main causative agents of gastrointestinal (GI) diseases in human and can cause both food poisoning (FP) and non-food-borne (NFB) diseases. Several factors contribute to the pathogenesis of C. perfringens type A strains including the wide presence of C. perfringens spores with...
Resource Type:: Dissertation
Full Text:: , I would like to thank the rest of my thesis committee: Dr. Daniel Rocky, Dr. Ling Jin, Dr, Joy

Targeted development of antivirals against influenza A and respiratory syncytial virus

Creator:: Lupfer, Christopher
Abstract:: Influenza A and Respiratory Syncytial Virus (RSV) are both enveloped, negative strand RNA viruses which infect the respiratory mucosa of animals and humans. Despite decades of research and development of antivirals and vaccines, both of these viruses continue to be a major health concern throughout the world. The focus of...
Resource Type:: Dissertation
Full Text:: progresses toward becoming a lysosome. As an ion channel, M2 protein allows for H+ ions to flow from the

ScholarsArchive@OSU

Investigation of cis-acting RNA element role in bovine viral diarrhea virus replication

Interaction of the Respiratory Syncytial Virus Matrix Protein and the Cellular Adaptor Protein Complex 3µ Subunit

Impact of Unfolded Protein Response, USP14, and NEDD8 Inhibitors Upon Antigen Presentation in SaI/Ak and 4T1 Tumor Cell Lines

Systemically Delivered Magnetic Hyperthermia for Cancer Treatment

Gene expression in the peripartum canine placenta

Effects of selenium supplementation during different trimesters of pregnancy on non-specific humoral immunity of pregnant beef cows and persistence of antibodies in their newborn calves

Multiplex real-time PCR in the detection and differentiation of bovine respiratory disease pathogens

Bacterial and Host Factors Contributing to Mycobacterium avium subspecies paratuberculosis Persistent Infection

Inactivation of Clostridium perfringens in Meat Products

Targeted development of antivirals against influenza A and respiratory syncytial virus

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