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Filtering by: Creator Lakatos, L��r��nt Creator Liu, Yu Ping

Small RNA binding is a common strategy to suppress RNA silencing by several viral suppressors

Creator:

Lakatos, Lóránt, Csorba, Tibor, Pantaleo, Vitantonio, Chapman, Elisabeth J., Carrington, James C., Liu, Yu-Ping, Dolja, Valerian V., Calvino, Lourdes Fernández, López-Moya, Juan José, and Burgyán, József

Abstract:

RNA silencing is an evolutionarily conserved system that functions as an antiviral mechanism in higher plants and insects. To counteract RNA silencing, viruses express silencing suppressors that interfere with both siRNA- and microRNA-guided silencing pathways. We used comparative in vitro and in vivo approaches to analyse the molecular mechanism of...

Resource Type:

Article

Full Text:

suppression L Lakatos et al &2006 European Molecular Biology Organization The EMBO Journal VOL 25 | NO 12
Generation of full-length cDNA clone and functional analysis of leader proteases of grapevine leafroll-associated virus-2

Creator:

Liu, Yu-Ping

Abstract:

Papain-like leader proteases are found in diverse families of human, animal, plant, and fungal positive-strand RNA viruses. In addition to autocatalytic processing, these proteases play a variety of roles in the virus life cycle. In particular, the leader protease (L-Pro) of a prototype member of the Closterovirus genus, Beet yellows...

Resource Type:

Dissertation

Full Text:

proteases play a variety of roles in the virus life cycle. In particular, the leader protease (L-Pro) of a