Deaf students in mainstream colleges are withdrawing at an alarming rate. Approximately 70% of the 123,000 deaf students enrolled in 2,300 colleges across the United States will not persist until graduation. This qualitative study examined what factors in the academic and social environment are linked to deaf college students' perceptions...
Men today are doing more household labor than in previous generations, but research suggests that gender still strongly influences household labor. A great deal of labor goes into creating family rituals, which may be central carriers for gender construction. Weddings, in particular, are rituals based on a gender dichotomy that...
Different racial/ethnic groups often perceive the realities of the campus environment differently: This difference in perspective and the attendant reactions can be a factor in student satisfaction or dissatisfaction. A quantitative survey administered in 1996 and 1999 revealed that African-American students on the campus of a diverse two-year community college...
Cancer is one of the leading causes of death in the U.S., and new approaches to control cancer are constantly sought. This dissertation is comprised of two parts: (i) improving the uptake and retention of gadolinium in tumors for potential gadoliniumneutron capture therapy (Gd-NCT) and (ii) integration of gemcitabine or...
This research work focuses on the mechanism of 1/f noise in GaAs
resistors on semi-insulating substrates and 1/f noise due to temperature
fluctuations in heat conduction in resistors, diodes, and bipolar transistors. The
goal of this research is to generate accurate models to explain physical origin of 1/f
noise in...
The purpose of this research was to develop and test a radiation detector to perform beta dosimetry and spectroscopy. The detector utilizes plastic scintillator volumes to produce scintillation light in proportion to the amount of energy deposited in them, and a large-area avalanche photodiode to convert the light to electrical...
Purpose: The purpose of this investigation was to identify a deep-water running (DWR) style that most closely approximates terrestrial running. Methods: Twenty healthy male and female intercollegiate (NCAA III) distance runners were videotaped from the right sagittal view while running on a treadmill (TR) and in deep water at 55-60%...
Presented here is a case study of the problem-solving behaviors of upper-division undergraduate physics majors. This study explores the role of visual representations in students' problem solving and provides a foundation for investigating how students' use of visualization changes in the upper-division physics major. Three independent studies were conducted on...
Since the passage of the Education for All Handicapped Children Act in 1975, a number of common problems have emerged. Primarily they involve the difficulties both experienced and created by public schools attempting to fulfill the federal mandate to provide students with disabilities an appropriate public education. The purpose of...
Ecosystem management has become an increasingly mainstream paradigm for natural
resource management. Nowhere is this more evident than on the public and private forestland
of the Pacific Northwest. While ecosystem management has become a widely
accepted principle of resource management, substantial questions remain about its
implementation. A case in point...
Angry driving behaviors that lead to acts of road rage have become a major public health concern. Understanding the differences between people who drive with a high level of anger and those who do not provides insight into possible prevention approaches. This study applied Richard Lazarus' Cognitive-Motivational-Relational (CMR) Model to...
Fuelwood is a basic need for rural households in Malawi. However, deforestation has reduced the quantity of forest products such as fuelwood available to households. This has negatively affected rural Malawian quality of life, especially for women who are forced to walk long distances to collect fuelwood, prepare foods with...
Globally intermittent turbulence is characterized by sudden switching from significant turbulence to weak turbulence and back on time scales ranging from seconds to tens of minutes as opposed to microscale intermittency, which is due to organization of small scale gradients by individual eddies on scales as small as the Kolmogorov...
The primary focus of this work is on examining structure-property relationships of interest for high-power nonlinear optical and laser crystals. An intuitive and simply illustrated method for assessing the nonlinear optical potential of structurally characterized noncentrosymmetric materials is introduced. This method is applied to materials including common quartz and tourmaline...
A Cost-Effectiveness Analysis of a targeted intervention for community control of Ascariasis was carried out in three rural communities near Quito, Ecuador. Targeted treatment with Paico (Chenopodium ambrosioides) and Albendazole (ABZ) was applied to children aged 5 to 15 years attending primary local schools in Aglla, Checa and Iguinaro. Prevalence...
Overweight and obesity are a growing national concern, particularly among women and selected minority populations (Ayala, Elder, Campbell, Slymen, Roy, Engelberg, et al., 2004; NHANES, 2003). Pregnant women bear a disproportionate risk of becoming overweight or obese (Greene, Smickikias-Wright, Scholl, & Karp, 1988; Gunderson et al., 2000; Rossner, 1999). Although...
Guided by Ogbu's cultural-ecological model of human development, this comparative study offers a comprehensive and explicit way of conceptualizing and measuring parenting within the cultural context. Multiple hypotheses are generated for the cross-cultural comparison of parenting styles in Asian Americans and European Americans. The study uses the National Longitudinal Study...
In many areas of the developing world, the continued overexploiting forest resources has the potential to have significant detrimental impacts be placed on sustainable forest management (SFM) can help communities and organizations responsibly manage and utilize the remaining forests over the long term. Ethiopia’s forest lands provide tangible benefits from...
Individual supervision is a widely accepted practice in the counseling profession, yet the tasks and focus of individual supervision in an agency setting remain largely uninvestigated. The tasks and focus areas inherent to agency supervision are especially important to counselors, counselor educators, agency administrators, and licensing boards, all of whom...
The purpose of this study was to develop a profile
of Christian College physical education faculty members
regarding their academic preparation, professional
experience, and selected duties, as well as to identify
important components of graduate preparation at the
doctoral level for future faculty at these
institutions.
A survey instrument was...
From 1990 to 2000, Oregon community colleges experienced a shift in their revenue sources from primarily local taxes to primarily state funding. Additionally during this time Oregon approved term limits for state officials and legislators. In preparation for the 2001-2003 biennial Legislative session, the community colleges pursued new approaches to...
The purpose of this study was to describe the presidential search process at a
newly created community college and to learn how that process reflected the
emerging organizational culture. A single research question guided the inquiry: How
did the presidential search process at a newly created community college reflect the...
An expedient approach to the synthesis of a wide range of highly programmable biaryl templates has been accomplished. Utilizing the Diels-Alder [4+2] cycloaddition, a wide range of tri- and tetra-ortho-substituted biaryls have been synthesized in only three to four steps from commercially available materials. We have successfully synthesized entire classes...
Commonly proposed ocean wave energy converters (OWEC) use inefficient and maintenance demanding intermediate hydraulic and pneumatic systems. We propose a novel rotary direct-drive OWEC that eliminates these intermediate stages. The new device employs a contactless force transmission system (CFTS) comprising a “piston” and a “cylinder” and a ball screw to...
With the development of high performance power electronic and semiconductor technologies, Adjustable Speed Drive (ASD) systems are increasingly applied in residential, commercial and industrial applications. Due to the advantages at higher power ratings, the three-level Neutral-Point-Clamped (NPC) Voltage Source Inverter (VSI) is being employed in industrial and traction applications, static...
Power quality has become an important concern to both electric utilities and
end users due to the increased use of non-linear loads in modem power systems
over the past decade. Nonlinear loads inject harmonics into the power system and
thus may lead to poor power quality and lower power factor....
This dissertation presents a dual-path 2-0 MASH (Multi-stAge-noise -SHaping) ADC with two verified digital corrections of DAC mismatch error and quantization noise leakage. By using these two techniques, the requirements for the analog circuits are greatly relaxed. The dual-path structure generates two outputs, one only composed of conversion errors, the...
The study of the infra-specific ranks (i.e., subspecies and variety) can be considered
the study of the process of speciation. Astragalus lentiginosus Douglas ex Hooker
(Fabaceae) is the most taxon rich species in the U.S. flora currently including 40
taxonomic varieties. These varieties were described using traditional taxonomic
methods primarily...
Despite recent efforts to improve site safety, construction still accounts for a disproportionate injury and illness rate. According to the 2007 injury and illness data released by the National Safety Council, the construction industry has a fatality and disabling injury rate that is approximately three times higher than the all-industry...
Taiwan has undergone significant social change, particularly in the last forty years, due to economic and industrial growth. Career development intervention is increasingly urgent in helping students face upcoming challenges. This study investigates the implementation and perceived helpfulness of career development interventions in Taiwanese comprehensive high schools. A total of...
Substance abuse is a prevalent occurrence among adolescents. A review of the
literature revealed that adolescent substance abuse has a strong connection to their
academic performance. School counselors address adolescents' academic and
personal/social needs by providing services through prevention education, responsive
services, and collaboration with community members. Yet, there is...
Suicide is currently the third leading cause of death for adolescents ages 15- 24. While much attention has been given to this topic, no research has examined what specific information is being taught to pre-service school counselors. The purpose of this descriptive study was to evaluate the pre-service suicide prevention...
This thesis proposes a novel fully digital technique for the estimation and correction of the DAC error in multi-bit delta sigma ADCs. The structure of the DAC error is indicated through a simple model for unit-element based DACs. The impact of the DAC error on the performance of ADC is...
New approaches are needed to quantify and understand spatial patterns of stream fishes and their environment. Concepts in riverine ecology emphasize the importance of thermal zones and gradual longitudinal changes in physical habitat and biota, but little is known about spatial variability within the river continuum. I present a conceptual...
This study described how and why a Korean elementary teacher taught mathematics as he did. Specifically, the study sought to describe his beliefs about the teaching and learning of mathematics and relate them to patterns of classroom interaction and norms.
An ethnographic inquiry guided the study of one third grade...
Western juniper has rapidly expanded into sagebrush steppe communities in the Intermountain West during the past 120 years. This expansion has occurred across a wide range of soil types and topographic positions. These plant communities, however, are typically treated in current peer-reviewed literature generically. The focus of this research is...
In the context of forest products, a cutting order is a list of dimension parts along with demanded quantities. The cutting-order problem is to minimize the total cost of filling the cutting order from a given lumber grade (or grades). Lumber of a given grade is supplied to the production...
The dominant controls on flow generation in steep, forested hillslopes are poorly understood. This dissertation examined the dominant flow processes operating at the hillslope scale, using a combined macroscale measurement and model development and analysis framework. Irrigation experiments at two steep forested hillslopes were conducted to isolate individual hillslope flow...
Occurrence of human error in highly complex systems, such as a cockpit, can be disastrous and/or overwhelmingly costly. Mismanagement of multiple concurrent tasks has been observed by researchers to be a type of repetitive human error in previous studies of accidents and incidents. This error may occur in the form...
The Penn-State/NCAR MM5 mesoscale model was adapted for mesoscale simulations of the Martian atmosphere (the OSU MMM5). The NASA Ames Mars GCM provides initial and boundary conditions. High-resolution maps for albedo, thermal inertia and topography were developed from Mars Global Surveyor (MGS) data; these baseline maps are processed to appropriate...
This research addresses the large-scale group fleet replacement problem with multiple vehicle types of multiple units, under budget and demand constraints. Past research in group fleet replacement is limited and has focused on one vehicle type, with multiples units and constraints. Many studies in fleet replacement have also dealt with...
Pollen development is an important process in male flower development, the timing of which may be correlated with time of pollen shed in hazelnut (Corylus avellana L.). Early to very late blooming cultivars were identified and the relationship of microsporogenesis and microgametogenesis, and time of pollen shed were studied in...
Increased global competition is forcing organizations to increase their use of group decision making today. Computerized group decision support aids (CGDSAs) are being developed to improve the efficiency of these groups and to improve decision quality. Even though the use of CGDSAs has increased, very little research has been done...
Digital-to-analog converters (DACs) with wide dynamic range and high
linearity are required for high-end audio applications. A multi-bit delta sigma
audio DAC, using a novel gain-correction technique, is described in this thesis. For
widely varying on-chip RC time constant, the DAC gain can be accurately
controlled by the correction circuitry....
Evolution of the mobile communication standards and proliferation of hand-held devices mandate stringent Analog-to-Digital Converter (ADC) specifications. Among various ADCs, a ∆Σ ADC is best known as a power-efficient ADC when more than 12b is required. However, a conventional discrete-time (DT) ∆Σ Modulator (∆ΣM) is inadequate for low-power wideband applications...
The National Council of Teachers of Mathematics published their vision of active, problem-centered instruction with a goal of conceptual understanding in 1989. Fifteen years after these reforms were proposed the changes are reflected in school policy and elementary mathematics curriculum, but only limited change has actually occurred in classroom instruction....
Physical distribution is one of the key functions in logistics systems, involving the flow of products from manufacturing plants or distribution centers through the network of transportation to consumers. The function is very costly, especially for the distribution industries. During the past decades, the significance of physical distribution has increased...
Using network architecture to describe a biological system is an effective organizational method. The utility of this approach, which generally applies to qualitative models, is enhanced by the addition of quantitative models characterizing the interactions between network nodes. A chromatophore-based signal transduction network is developed, and the highly interconnected major...
The main result of this written dissertation is a mathematical solution to the problem of multiplex recording for high performance tandem time-of-flight mass spectrometry. The prescription is to use a time-lag accelerator in the second stage to match the ion optical properties of the decay fragments to the requirements of...
The use of an adjacency matrix to determine distant (not maximal or
minimal) subgroup and supergroup relationships between crystallographic spacegroup
types is described. Full lists of space-group types that are supergroups and
subgroups for every space-group type were compiled. A list of the space-group
types connected to each space-group type...
In this work, a multicomponent lattice Boltzmann model is developed for the simulation of multiphase mixing, reactions, and separations processes. This model is unique in that diffusive mass transfer of a component in the model is driven by gradients of chemical potential. This fundamentally correct description of diffusion accurately captures...
Targeting the epigenome, including the use of histone deacetylase (HDAC) inhibitors, is a novel strategy for cancer chemoprevention. Sulforaphane (SFN), a compound found at high levels in broccoli and broccoli sprouts, is a potent inducer of Phase 2 detoxification enzymes and inhibits tumorigenesis in animal models. SFN also has a...
This thesis describes evaluation of a novel self-sealing chewable sustained release tablet that can maintain controlled release of drug regardless of compaction, crushing, or chewing. The new formulation contains polyethylene oxide which produces a sealant effect for cracks produced in the polymer coating during compaction. Dissolution studies were conducted and...
The spread of the internet and communications techniques increases the necessity
for security in applications that involves sharing or exchange of secret or private infor-
mation. Public-key cryptography is widely used in establishing secure communication
channels between the users on the Internet, for E-commerce transactions, and in net-
work security...
A per-segment classification system was developed to map aspen (Populus tremuloides) stands on Winter Ridge in central Oregon from remote sensing imagery. A 1-meter color infrared (CIR) image was segmented based on its hue and saturation values to generate aspen "candidates", which were then classified to show aspen coverage according...
Although perceived-risk curriculum, that is, where the learner experiences effects of eustress (positive stress), has been used in Arts or outdoor activities, it has not been used in school classrooms. Milkman’s 1996 studies of after-school Project Self Discovery demonstrated that at-risk students lessened their adverse risky behaviors, such as substance...
The Mount Fubilan Intrusion is part of a geologically young hypabyssal stock in the Star Mountains of Papua New Guinea. This stock was mapped as the Ok Tedi Intrusive Complex and divided into four separate bodies: the Mount Fubilan, Sydney Intrusion, Kalgoorlie, and Ningi Intrusions. Hydrothermal fluids caused alteration of...
This phenomenological inquiry explored dimensions of reflection for older adults in a developmental oriented adventure education experience. Data were gathered from emergent interviews with four individuals while participating in a multi-day, self-contained experiential education program conducted in a rugged environment, and led by a Navajo leader. Two principle research questions...
This is a study of the process of collaboration between a community college and selected social service agencies for the purpose of developing an integrative social service and education delivery system, the One-Stop Center. Particular focus is on the interpersonal dynamics among the key stakeholders involved in a collaborative partnership....
In the United States, falls are the leading cause of unintentional death with one of every three people 65 years and older falling each year. Falls account for approximately 95% of hip fractures among older adults and falls to the side predominate hip fracture related falls in this population. However,...
Protein disulfide isomerase (PDI), a member of the thioredoxin superfamily, contains two domains with significant sequence homology to the active sites in thioredoxin. PDI facilitates the folding of nascent proteins in the endoplasmic reticulum (ER), binds hormones and Ca²⁺, catalyzes the glutathione dependent reduction of dehydroascorbate, serves as a major...
The purpose of this qualitative study was to research the experience of six Hispanic students who were interviewed in depth regarding their persistence in school and success at a community college. The students reported on their educational experiences prior to college and how that related to attendance at the college;...
ROP GTPases are crucial regulators of pollen tube growth. The Rop GTPase family in maize consists of nine known rop genes, ropl-rop9. A subset of these genes (rop2, rop8, and rop9) are expressed in pollen. The rop2 and rop9 genes are a highly conserved duplicate gene pair of ancient origin....
Conceptually, the dynamics of wood in streams can be viewed in terms of input and in-channel processes. Input processes are associated with both the riparian (tree fall, bank cutting, windthrow) and upslope forests (mass failures). In-channel processes include log breakage, movement, and decomposition. A mechanistic view of these processes is...
A one-dimensional numerical model has been developed to study diabatic and adiabatic
flow boiling in microchannels. This model accounts for developing flow effects and
variable property effects. The model uses correlations for void fraction and two-phase
multipliers found in the literature. The model has been used to study the performance...
The purpose of this study was to understand how adult learners in an online teacher licensure program selected and used learning strategies, transformed existing strategies or developed new strategies. Also examined was whether the environment itself facilitated or impeded usage of transformed strategies, or development of new strategies. Participants in...
Cavitation instabilities in elastic-plastic solids under spherically-symmetric and axisymmetric loadings were investigated using the finite element method. Both quasi-static and dynamic analyses were used to solve these problems. In the quasi-static analyses, we investigated a cavitation instability in elastic/perfectly-plastic, linear hardening elastic-plastic, power hardening elasticplastic, and constrained silver materials. Here,...
This dissertation reviews the literature on the specialty area of dolphin assisted therapy (DAT), a subfield of animal assisted therapy (AAT). To date the literature on the effectiveness of DAT has been mixed although a majority of it is positive. The study was conducted with 40 parents whose children were...
There is a wealth of research on issues surrounding teacher burnout and school reform. The literature on burnout, however, does not provide information on system-based burnout prevention models. Comprehensive reform, although intended to improve schools as a whole, does not look at reform models developed as sources of teacher support....
North America, with over 400 species of Astragalus (Fabaceae), is one of three major centers of diversity, all of which comprise the majority of the nearly 1750 species of Astragalus worldwide. One of the most diverse species, Astragalus lentiginosus of Section Diphysi, is a polymorphic complex of over 40 varieties,...
Objectives The purpose of this study was to investigate the need for a technology acquisition tool to be used in the capital purchasing process in health care organizations.
Design Multi-method approach consisting of interviews of ten executives of health care organizations. A written survey was then mailed to Chief Executive...
The thermodynamic and structural effects of highly anisotropic, short-ranged attraction are investigated for single- and four-site interaction models using Wertheim's multi-density graph theory of chemical association. Both models consist of associating hard spheres, where the saturable attraction sites are described by conical wells centered in the hard core and evaluated...
An improved version of the one-dimensional horizontal two-fluid flow model has been developed by incorporating physical terms for gravity and local void fraction profiles. Introduction of an interface mixing layer concept allows the one-dimensional two-fluid model to remain hyperbolic. This will overcomes a major obstacle in using the current one-dimensional...
The focus of this study is a search for the voice of African American community college trustees as they work to impact the changes community colleges must make over the next quarter century. It examined the lived experiences and perceptions that selected African American community college trustees have of their...
Delta-Sigma (ΔΣ) analog-to-digital converters (ADCs) are widely used in wireless transceivers. Recently, continuous-time (CT) ΔΣ ADCs gain growing interest in wireless applications for their lower power consumption and wider input bandwidth as compared with the discrete-time (DT) counterparts.
In this thesis, a wideband low-power CT ΔΣ modulator for next generation...
A. W. N. Pugin was a driving force in the Gothic Revival movement in England during the first half of the nineteenth century. He was an architect and a writer who expounded on the virtues of reviving Gothic architecture, not only for its reflection of the sacred mystery of ancient...
Carbon sequestration in tropical secondary forests growing in all climates must be quantified to understand their potential role in adaptation and mitigation strategies of global climate change. Total aboveground biomass (TAGB), soil carbon, and total ecosystem carbon (TEC) were measured in 54 secondary forests growing along a broad bioclimatic gradient...
This qualitative study explored the life experiences of a small group of
Yemeni women who are academically successful and identified factors perceived by this group to have played a major role in their academic success. One of the key objectives was to gain a better understanding of the processes which...
Academic achievement of adolescent children is directly associated with their success in adulthood. Little is known, however, regarding how adolescents in immigrant families academically grow over time and what factors influence the trajectories. Drawing on the National Educational Longitudinal Survey 1988 (NELS: 88), this study aimed to: 1) identify the...
This phenomenological inquiry explored the experiences of library leaders and discipline faculty members engaging in a collaborative instructional change initiative focused on a process-based learning pedagogy and led by an academic library. The investigation’s purpose was providing insight and understanding concerning the: (a) library’s role in instructional leadership; (b) experience...
4-nonylphenol (NP), a surfactant degradation product, is an unregulated, ubiquitous aquatic contaminant and endocrine disruptor, for which aquatic life criteria are currently under development by U.S. EPA. The effects of NP on estuarine amphipods and chinook salmon fry were investigated, and this dissertation reports research into the impacts of NP...
Pipelined analog to digital converters (ADCs) are very important building blocks in many electronic systems such as high quality video systems, high performance digital communication systems and high speed data acquisition systems. The rapid development of these applications is driving the design of pipeline ADCs towards higher speed, higher dynamic...
The U.S. Department of Health and Human Services has made the promotion of regular physical activity a national health objective, and experts believe that physical education can play a significant role in the promotion of physical activity. Feasible measurement tools to assess physical activity behavior, by physical educators, are lacking....
A series of compounds, 7-8 and 20-25, were tested as competitive inhibitors of 2,5-dihydroxyacetanilide epoxidase I (DHAE I) and DHAE II. A Hammett plot was constructed for each enzyme to determine the effect of electron density on inhibition. DHAE I gave a linear, highly correlated plot (r²=0.91) that signifies the...
Knowledge workers are struggling in the information flood. There is a growing interest in intelligent desktop environments that help knowledge workers organize their daily life. Intelligent desktop environments allow the desktop user to define a set of “activities” that characterize the user’s desktop work. These environments then attempt to identify...
Piliostigma reticulatum and Guiera senegalensis are two native shrubs that
coexist with row crops in parkland systems of the Sahel of Africa. Although
permanently green all year around in soil depleted in nutrients and dry for a nine-month
period, these shrubs have been largely overlooked. Conventional management of these
shrubs...
Although female athletes are at greater risk of non-contact knee injuries than men, the factors that contribute to these injuries are not well understood. One important question is whether intense exercise influences the risk of knee injury, both acutely
and over the following days. The purpose of this study was...
Two specific goals were addressed for this dissertation. First to investigate and identify the mechanistic profile of ketoconazole (KT)-induced hepatotoxicity by utilizing in vivo and in vitro approaches determining the mechanism of action for the hepatotoxicity incurred. To date, there has not been a mechanistic determination of the hepatotoxicity associated...
The acute phase response (APR) includes an early response of the innate immune
system to an inflammatory agent. Acute phase proteins (APP) are produced at
increased rates in the liver during this response. The APR has been well
characterized in mammals, but it is unclear to what degree teleosts mount...
In this dissertation I study evolutionary patterns at genes encoding antimicrobial peptides (AMPs) in frogs. AMPs are short, amphipathic, cationic, secreted proteins that kill bacteria and other pathogens through a non-catalytic mechanism that involves
binding to and disrupting the microbial cell membrane. In many animal taxa, positive selection is much...
The exponential rate of advances in modern communication devices in the last several years have brought us higher levels of functionality and performance as well as reductions in physical size and power consumption. To continue this rate of advancement, next generation systems require wider bandwidth and higher resolution ADCs. Additionally,...
The primary purpose of this study was to determine which factors related to adult 4-H volunteer empowerment in 4-H youth development settings. This study examined the relationship of adult 4-H volunteers’ perceived leadership styles of Oregon 4-H Youth Development Educators (YDE) to the adult 4-H volunteer sense of empowerment. In...
In modern on-chip memories, an increasing demand for higher performance, lower power, reduced area, and improved robustness creates a rising need for advanced microarchitecture and circuit design techniques. Particularly in large-signal multi-ported register files, these advanced design techniques include: (i) multi-banked arrays, (ii) multi-frequency arrays, (iii) multi-bit width gating, (iv)...
Traditionally linear actuator applications are addressed by the use of hydraulic systems. The high maintenance cost and poor reliability will always be the most critical problem in the real applications. Benefited from both the high mechanical advantage of the roll screw and the simple structure of the switched reluctance motor,...
The appropriate separation of concerns is a fundamental engineering principle. A concern, for software developers, is that which must be represented by code in a program; by extension, separation of concerns is the ability to represent a single concern in a single appropriate programming language construct. Advanced separation of concerns...
L-pipecolic acid (L-PA) is the higher homolog of proline. It occurs naturally in
many organisms, including primates, as an intermediate in lysine degradation. The
pathway by which lysine is converted into L-pipecolic acid employs the enzyme Lpipecolate
oxidase (L-PO), and appears to be tissue specific to the central nervous system...
Streptococcus gordonii is a bacterial species that naturally colonizes the oral cavity of most healthy humans. It resides in the mouth as an adherent to dental surfaces and, with few exceptions, does not cause disease in individuals it inhabits. It possesses qualities that encourage its use as a vector to...