Canine Transitional Cell Carcinoma (TCC) makes up 2% of all canine cancers and is the most common cancer of the bladder for dogs. Usually diagnosed in its later stages, TCC is difficult to treat, with low survival times. Current diagnosis involves invasive techniques, and mainstream screening tests are often ineffective....
The Boulder Batholith and Elkhorn Mountains Volcanics (EMV) formed concurrently during shortening between ~85-76 Ma near the end of Mesozoic Cordillera arc magmatism. Together they represent an exceptionally well-preserved and voluminous record of continental arc magmatism. We report field and analytical results from studies of the EMV and Boulder Batholith...
Utilization and preference of whelk shells by the hairy hermit crab are examined in the following to further define the ecology of Oregon’s mid to low intertidal ecosystems. The study was conducted at Tokatee Kloochman State Natural Area (TK) where I made observations before collecting data. My observations were of...
Over half of the U.S. coastline is found in Alaska, and the majority of the state’s economic activity occurs along the coast. Increased coastal development poses a potential threat to nearshore habitats in Alaska. The installation of artificial reef (AR) systems can mitigate habitat loss; however, few AR systems have...
The quality of relationships in early childhood have lasting effects on children’s academic and behavioral success. Teacher report is the most widely used measure to assess the quality of the teacher-child relationship, however teachers are often biased by the child’s behavior. Observed quality of the relationship may illustrate differences in...
Carcinus maenas is an invasive marine predator. Its generalist feeding strategies make it one of the most effective invaders. Carcinus maenas has invasive populations throughout the world, and was recently introduced to the west coast of North America. This study looks at the abundance and growth of C. maenas in...
Over 70% of the Antarctic krill population exists along the Antarctic Peninsula, a region undergoing rapid climate change. Recent studies have shown a clear correlation between krill recruitment each spring and the timing and coverage of sea ice the winter before, with less sea ice and a shorter duration being...
Self-directed mobility is a fundamental human right. Typically developing children engage in mobility for a majority of their day, but children with disabilities do not have the same opportunities. Children with disabilities are at a disadvantage and have a greater risk for developmental delays in physical and cognitive skills, along...
A novel approach for the colorimetric detection of creatinine in a paper/polycaprolactone hybrid microfluidic device using alkaline3,5-dinitrobenzoate (DNB) is described. The reaction parameters of reagent concentration, alkalinity, and analysis time are optimized for fast reaction times and high color yield. Microfluidic devices incorporating this assay are designed and fabricated to...
During fall term of 2015 and winter and spring term of 2016 I assisted in research within Dr. Emily Ho’s lab. The project that I assisted in looked at the effects of low zinc status and arsenic exposure in mice. Zinc is an essential micronutrient involved in numerous cellular processes...
The hypothalamic neuropeptide kisspeptin (Kiss-1) acts as a central component of the reproductive axis. A critical factor in pubertal progression and normal reproduction, this peptide is an afferent stimulator of gonadotropin-releasing hormone (GnRH), and is responsive to gonadal steroids, integrating steroid hormone signals and modulating GnRH secretion accordingly. Kiss-1 exhibits...
Diet History Questionnaires (DHQ) can only provide general information about a person’s nutritional intake. It is unable to cluster groups of people based on diets or lifestyles, nor identify specific foods that may play a role in disease prevention. The aim of this study was to validate the use of...
4-H, an agriculture based youth program, promotes a variety of curricula in both agriculture and Science, Technology, Engineering and Math (S.T.E.M.) topics. However, science based curricula provided by this organization gravitates away from the programs agricultural roots. An effort was made to pilot a test on lesson plans that would...
Gene expression in plants (and other eukaryotes) is a very complex process. Gene expression is primarily controlled by proteins and their binding sites near the gene in the chromosomal DNA. More specifically, interactions among transcription factors (DNA-binding proteins) and cis-regulatory modules (CRMs-sets of binding sites) control the expression of nearby...
Cystic ovarian disease (COD) is one of the main causes of infertility in dairy cattle and has a high economic impact on farmers. COD is caused by an endocrine imbalance within the hypothalamic-pituitary-ovarian axis which prevents the mature Graafian follicle from ovulating. The cause at the molecular level is not...
Monitoring the concentration of phenolic compounds is important for environmental regulation, health diagnostics, and bioenergy fermentation. Vanillin is a phenol compound used as a food flavoring that can cause allergies and inhibits biofuel production. The phenol m-cresol is a toxic compound that is regulated in the environment and in human...
Genetic engineering techniques allow scientists to create plants with desired traits. However, there is unwanted variability in transgene expression due to enhancer-promoter interactions and the influence from genetic elements near the insertion site of the transgene, which integrates into a random location in the genome. In an attempt to reduce...
Research in Dolan lab focuses primarily on the adaptive immune system and ways it can be better utilized to eliminate infected or transformed cells. Research focuses on the major histocompatibility (MHC) class I antigen presentation pathway, which plays an important role in alerting the immune system of the presence of...