Various flavonoid-rich plant extracts have shown efficacy in the treatment of diabetes. Although it is often assumed that dietary flavonoids exert biological antioxidant effects, it is possible that the observed effects work in carbohydrate metabolism. In this study we evaluated the effect of catechins and catechin containing extracts on α-amylase...
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BalzFrei
Various flavonoid-rich plant extracts have shown efficacy in the treatment of
Various flavonoid-rich plant extracts have shown efficacy in the treatment of diabetes. Although it is often assumed that dietary flavonoids exert biological antioxidant effects, it is possible that the observed effects work in carbohydrate metabolism. In this study we evaluated the effect of catechins and catechin containing extracts on α-amylase...
:
_______________________________________________________________________________________________
BalzFrei
Various flavonoid-rich plant extracts have shown efficacy in the treatment of
Atherosclerosis is the underlying cause of ischemic heart disease and stroke and is the leading cause of death worldwide, especially in developed countries. As an inflammatory disease of arteries in a hyperlipidemic milieu, expression of adhesion molecules, such as endothelial-leukocyte adhesion molecule-1 (E-selectin) and intercellular adhesion molecule-1 (ICAM-1), on endothelial...
In this study we investigated the role of astragaloside IV (AS-IV), one of the major active constituents purified from the Chinese
medicinal herb Astragalus membranaceus, in LPS-induced acute inflammatory responses in mice in vivo and examined possible
underlying mechanisms. Mice were assigned to four groups: vehicle-treated control animals; AS-IV-treated animals...
Research progress to understand the role of vitamin C (ascorbic acid) in human health has been slow in coming. This is predominantly the result of several flawed approaches to study design, often lacking a full appreciation of the redox chemistry and biology of ascorbic acid. In this review, we summarize...
The recommended dietary allowance (RDA) of vitamin C has traditionally been based on the prevention of the vitamin C deficiency disease, scurvy. While higher intakes of vitamin C may exert additional health benefits, the limited Phase III randomized placebo-controlled trials (RCTs) of vitamin C supplementation have not found consistent benefit...
We reviewed recent scientific evidence regarding the effects of MVM [multivitamin/mineral] supplements on risk of chronic diseases, including cancer, cardiovascular disease, and age-related eye diseases. Data from both randomized controlled trials (RCTs) and observational, prospective cohort studies were examined. The majority of scientific studies investigating the use of MVM supplements...
Inhibiting pancreatic lipase activity is an effective means of reducing fat absorption, which may have a role in combating obesity by limiting energy intake. The use of pharmaceutical lipase inhibitors has been limited due to the prevalence of undesirable side effects. Polyphenols represent an alternative strategy to inhibit digestive enzymes...
Ceramides are a group of lipids in the sphingolipid family that are potent cell signaling molecules. Elevations in ceramide levels above the norm generally lead to apoptosis. Evidence from in vitro studies suggests that accumulation of ceramides within mitochondria leads to dysfunction of the mitochondria. This includes inhibition of the...
Nuclear Factor, Erythroid Derived 2, Like 2 (NFE2L2 or Nrf2) is the primary transcription factor in cellular defense against oxidative and xenobiotic stresses in higher eukaryotes. This basic leucine zipper transcription factor regulates over 200 antioxidant, detoxification, and lipid metabolizing genes by binding to the Antioxidant Response Element (ARE; a...