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Filtering by: Committee Member Alani, Adam Remove constraint Committee Member: Alani, Adam Decade 2020-2029 Remove constraint Decade: 2020-2029

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  • Advancing Nanotechnology for Photoacoustic Imaging

    Creator:
    St Lorenz, Anna
    Abstract:
    Curbing overall disease burden with faster intervention requires early stage and accurate diagnostics. Ultrasound (US) provides a safe, nonionizing, inexpensive, and noninvasive imaging modality that has become commonplace in diagnostics. Paired with the relatively new technology of photoacoustic imaging (PAI), optical level resolution becomes feasible with the deeper signal penetration...
    Resource Type:
    Dissertation
    Full Text:
    Taratula, Dr. Theresa Filtz, Dr. Adam Alani, Dr. Claudia Hase. Chapter 1 This chapter was written by

  • Development of Novel Therapeutic Approach for Ewing’s Sarcoma Treatment

    Creator:
    Sabei, Fahad Yahya
    Abstract:
    Ewing sarcoma (EwS) is the second most highly malignant tumor that arises mainly from bone and surrounding soft tissue of adolescent and young adult patients. Despite the advances in Ewing sarcoma treatment that today include a combination of five chemotherapeutic agents, surgery, and/or radiotherapy, these therapies have demonstrated limited improvement...
    Resource Type:
    Dissertation
    Full Text:
    would like to thank all of my committee members, Drs. Adam Alani, Gaurav Sahay, Jung Kwon for their

  • Inhalable Lipid Nanoparticles for Messenger RNA Therapeutics

    Creator:
    Kim, Jeonghwan
    Abstract:
    Messenger RNA (mRNA) therapy has massive potential to treat various genetic disorders by providing effective proteins to the diseased cells and tissues. Its therapeutic applications include protein replacement, genome editing, and immunotherapy. For successful mRNA treatment, mRNA must be delivered to the cytosol of target cells. One of the leading...
    Resource Type:
    Dissertation
    Full Text:
    like to thank my thesis committee, Prof. Adam Alani, Prof. Conroy Sun, Prof. Arup Indra, and Prof

  • Investigating Multimodal Therapies with Nanotechnology to Engineer Advanced Chemoradiation Platforms

    Creator:
    DuRoss, Allison N.
    Abstract:
    The potential for nanomedicine to reduce toxicity and improve therapeutic response to radiation is vast. Clinically, this potential has thus far only begun to be realized with the recent success of the radioenhancing nanoparticle, NBTXR3 by Nanobiotix. Radioenhancing nanoparticles, however, represent only a small class of nanomaterials that may be...
    Resource Type:
    Dissertation
    Full Text:
    person and scientist that exists today. To my committee members, Dr. Adam Alani, Dr. Cecily Bishop