Index Catalog // ScholarsArchive@OSU

Engineering an Ex-Vivo System to Study Transport Phenomena in the Human Intervertebral Disc

Creator:: Shalash, Ward
Abstract:: Back pain is the leading cause of disability worldwide, entailing a significant socioeconomic impact. A primary source of back pain can be attributed to intervertebral disc (IVD) degeneration allowing nerve ingrowth, facet joint arthritis, disc bulging, and osteophyte formations that press on nearby nerve roots or the spinal cord. While...
Resource Type:: Dissertation
Full Text:: . 2017; Wang et al. 2016b; Zhou et al. 2016; Iatridis and ap Gwynn 2004). However, studies point to

Effect of Polyethylene Oxide (PEO) Modification on the Structure and Antimicrobial Activity of the Antimicrobial Peptide WLBU2

Creator:: Raper, Miranda A.
Abstract:: Sepsis is a blood infection that is caused by circulating bacteria cells and cell fragments, which contain immunogenic lipopolysaccharides (LPS) or endotoxin. The circulating endotoxin results in a severe dysregulation of the inflammatory response that ultimately leads to organ failure. One promising treatment method is removal of endotoxin by passing...
Resource Type:: Honors College Thesis
Full Text:: undergraduate career. Thanks to Dr. Kain Wu and Dr. Kerry McPhail for teaching me how to use and

Investigating the Role of Inflammation and Mechanical Loading in Orthopaedic Tissue Degeneration

Creator:: Benage, Lindsay G.
Abstract:: Orthopaedic soft tissue degenerative diseases significantly affect the population, especially as it ages. Degeneration is characterized by a progressive loss of extracellular matrix (ECM) components necessary for the proper functioning of the tissues and joints, eventually leading to pain and dysfunction. In humans, the intervertebral disc (IVD) and tendon are...
Resource Type:: Dissertation

Self Assembly of GeO₂ Nanoparticles: A Biomimetic Approach

Creator:: Gessford, Makayla SueAnn Fu Ting
Abstract:: Diatoms are single celled eukaryotic microalgae that self-assemble complex SiO₂ nanostructures by sillafin proteins within their cell wall. There has been increasing interest in mimicking the diatom’s silica self-assembly process for fabricating metal oxide nanoparticles, namely germanium dioxide (GeO₂). GeO₂ has a higher refractive index than silica, enabling it to...
Resource Type:: Honors College Thesis
Full Text:: , Zhongjun Chen, Wei Wang, Ziju Wu, and Zhonghua Wu. "Synthesis and Growth of Germanium Oxide Nanoparticles

Developing a Modular Analysis Pipeline to Identify Critical Matrisome Components in Gynecological Disease

Creator:: Cook, Carson J.
Abstract:: The matrisome is an ensemble of genes that are highly relevant for characterizing the behavior of the extracellular matrix (ECM) during the onset and progression of many diseases. Recent advances in the definition of the matrisome, such as The Matrisome Project, have been instrumental in making more advanced resources available...
Resource Type:: Masters Thesis

Effect of Reaction Parameters on the Catalytic Oxidation of Poplar Lignin

Creator:: Lu, Lin
Abstract:: Nowadays, woody biomass is becoming increasingly significant because of its renewability and biodegradability. Lots of opportunities have been found to use excessive biological resources to derive products as diverse as fuels, heat, electricity, chemicals, food, clothing, paper, and much more. As such, biomass plays an important role in meeting demands...
Resource Type:: Honors College Thesis
Full Text:: [1] A. Xu, X. Guo, Y. Zhang, Z. Li, and J. Wang, “Efficient and sustainable solvents for lignin

Precision Medicine for the Intervertebral Disc: Image Processing and Computational Modeling of Disc Degeneration to Inform Patient-Specific Therapies

Creator:: Ahrens, Sonia R.
Abstract:: The human intervertebral disc is a deceptively simple structure which plays an essential role in human movement. Even slight changes to the disc microenvironment can have far reaching consequences, particularly when these changes result in disc degeneration and herniation. Degeneration is increasingly tied to lower back pain; better understanding this...
Resource Type:: Masters Thesis

Ink and Substrate Compatibility for Electrochemical Sensing in Paper-based Devices

Creator:: Reid, Caitlin A.
Abstract:: Electrochemical sensing provides a quantitative alternative to colorimetric reactions within paper-based devices. The paper-based devices were fabricated by screen printing the conductive and reference inks onto porous substrates that were evaluated using cyclic voltammetry. Devices were evaluated based on the magnitude of the average anodic peak height, which correlates with...
Resource Type:: Honors College Thesis
Full Text:: the color change that occurs within the devices (Wang, 2011). An alternative to colorimetric

Use of ultrasound and magnetic resonance image processing for evaluation of supraspinatus and biceps tendon pathology in dogs

Creator:: Sheikh, Omar
Abstract:: Shoulder injuries, especially those caused by rotator cuff tears, are a pervasive problem in human and canine patients. The ability to quickly and accurately diagnose rotator cuff tears is important for early and targeted treatment. Prior clinical work has demonstrated that ultrasound and magnetic resonance imaging effectively diagnose these tears....
Resource Type:: Masters Thesis

Development of Rapid Diagnostic Tools for Personal Health Monitors in the Context of Therapy Monitoring

Creator:: Wentland, Lael T.
Abstract:: Personal health monitoring tools, a subset of point-of care-diagnostics, enable more frequent testing of chronic health conditions outside of a clinic setting and can inform personalized therapy or support telehealth diagnostic capabilities. While there is evidence that regular monitoring of chronic conditions can lead to better health outcomes and lower...
Resource Type:: Dissertation

ScholarsArchive@OSU

Engineering an Ex-Vivo System to Study Transport Phenomena in the Human Intervertebral Disc

Effect of Polyethylene Oxide (PEO) Modification on the Structure and Antimicrobial Activity of the Antimicrobial Peptide WLBU2

Investigating the Role of Inflammation and Mechanical Loading in Orthopaedic Tissue Degeneration

Self Assembly of GeO₂ Nanoparticles: A Biomimetic Approach

Developing a Modular Analysis Pipeline to Identify Critical Matrisome Components in Gynecological Disease

Effect of Reaction Parameters on the Catalytic Oxidation of Poplar Lignin

Precision Medicine for the Intervertebral Disc: Image Processing and Computational Modeling of Disc Degeneration to Inform Patient-Specific Therapies

Ink and Substrate Compatibility for Electrochemical Sensing in Paper-based Devices

Use of ultrasound and magnetic resonance image processing for evaluation of supraspinatus and biceps tendon pathology in dogs

Development of Rapid Diagnostic Tools for Personal Health Monitors in the Context of Therapy Monitoring

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